ID31657088
Published Date2019-12-19
JournalAngewandte Chemie (International ed. in English), 2019-12-19, Volume 58 Find other publications in this journal
Author Info
  • School of Chemistry, UNSW Sydney, Sydney, NSW, 2052, Australia.
  • Nanoscale Group, School of Science and Health, Western Sydney University, Penrith, NSW, 2751, Australia.
  • Department of Physics, University of Maine, Orono, ME, 04469-5709, USA.

Abstract

Intriguing reports of enhanced diffusion in enzymes and molecular catalysts have spurred significant interest in experimental and theoretical investigations, and the mechanism of this phenomenon is the topic of lively debate. Here we use time-resolved diffusion NMR methods to measure the diffusion coefficients (D) of small molecule species involved in chemical reactions with high temporal resolution. We show the enhanced diffusion of small molecules cannot be explained by reaction velocity, and that apparent measurements of enhanced diffusion by small molecules appear to be caused by bulk fluid flow processes such as convection.