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Research Grant
Award Number1916797Funding AgencyNational Science FoundationEffective Date2019-06-01Expiration Date2020-05-31Funding Amount$82,681
Innovations in plant science are needed to tackle global sustainability, food security and human health. Plants not only form the foundation of terrestrial ecosystems and the human food supply, but also provide renewable energy and essential medicines. The goal of this workshop is to bring together scientists from the fields of data science and bioinformatics, imaging, proteomics, single cell profiling and nanotechnology to brainstorm and develop tools to lay the groundwork for creating a com…
Patent
Publication NumberEP 3468533 A1StatusPatent ApplicationAvailabilityUnknownFiling Date2017-06-09Publication Date2019-04-17
Patent
Publication NumberKR 20190019129 AStatusPatent ApplicationAvailabilityUnknownFiling Date2017-06-09Publication Date2019-02-26
Described herein are nanostraw well insert apparatuses (e.g., devices and systems) that include nanotubes extending through and out of a membrane so that a material can pass through the membrane from a fluid reservoir depot and into a cell grown onto the nanotubes when electrical energy (e.g., electroporation energy) is applied. In particular, the device, systems and methods described herein may be adapted for cell growth viability and transfection efficiency (e.g., >70%). These apparatuses m…
Patent
Publication NumberWO 2019018415 A1StatusPatent ApplicationAvailabilityUnknownFiling Date2018-07-17Publication Date2019-01-24
Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery metho…
Patent
Publication NumberUS 20190024122StatusPatent ApplicationAvailabilityUnknownFiling Date2018-07-17Publication Date2019-01-24
Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery metho…
Patent
Publication NumberUS 10150947StatusIssued PatentAvailabilityUnknownFiling Date2016-01-08Publication Date2018-12-11
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.
Patent
Publication NumberAU 2017278095 A1StatusPatent ApplicationAvailabilityUnknownFiling Date2017-06-09Publication Date2018-12-06
Described herein are nanostraw well insert apparatuses (e.g., devices and systems) that include nanotubes extending through and out of a membrane so that a material can pass through the membrane from a fluid reservoir depot and into a cell grown onto the nanotubes when electrical energy (e.g., electroporation energy) is applied. In particular, the device, systems and methods described herein may be adapted for cell growth viability and transfection efficiency (e.g., >70%). These apparatuses m…
Patent
Publication NumberWO 2018183967 A1StatusPatent ApplicationAvailabilityUnknownFiling Date2018-03-30Publication Date2018-10-04
Systems and methods for manufacturing and processing microwires for use as microelectrodes are disclosed. The disclosed techniques provide methods for creating microelectrode bundles with different organizations and patterns. Systems and methods of the present disclosure also provide methods for electrochemically modifying bundles of microelectrode ends.
Publication
ID30192607Published Date2018-08-24JournalPhysical review letters, 2018-08-24, Volume 121
We demonstrate cavity-enhanced Raman emission from a single atomic defect in a solid. Our platform is a single silicon-vacancy center in diamond coupled with a monolithic diamond photonic crystal cavity. The cavity enables an unprecedented frequency tuning range of the Raman emission (100 GHz) that significantly exceeds the spectral inhomogeneity of silicon-vacancy centers in diamond nanostructures. We also show that the cavity selectively suppresses the phonon-induced spontaneous emission th…
Publication
ID30068609Published Date2018-08-14JournalProceedings of the National Academy of Sciences of the United States of America, 2018-08-14, Volume 115
Nucleation is a core scientific concept that describes the formation of new phases and materials. While classical nucleation theory is applied across wide-ranging fields, nucleation energy landscapes have never been directly measured at the atomic level, and experiments suggest that nucleation rates often greatly exceed the predictions of classical nucleation theory. Multistep nucleation via metastable states could explain unexpectedly rapid nucleation in many contexts, yet experimental energ…
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Research Grants: 16
Publications: 28
Patents: 26

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