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Patent
Publication NumberEP 2010918 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2007-04-13Publication Date2011-11-23
Patent
Publication NumberUS 20100178651Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-11-05Publication Date2010-07-15
The present invention provides the identification of genes that are expressed in tumors to indicate responsiveness or resistance to an agent or class of agents. More particularly, these genes show expression associated with responsiveness to one agent or class of agents is inversely related to expression in association with another class of agents. One or more of theses genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be succes…
Patent
Publication NumberEP 2094870 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-11-05Publication Date2009-09-02
Patent
Publication NumberWO 2008073629 A9Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-11-05Publication Date2008-09-25
The present invention provides the identification of genes that are expressed in tumors to indicate responsiveness or resistance to an agent or class of agents. More particularly, these genes show expression associated with responsiveness to one agent or class of agents is inversely related to expression in association with another class of agents. One or more of theses genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be succes…
Patent
Publication NumberWO 2007120806 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-13Publication Date2007-10-25
Disclosed is a method for determining survival and relapse of a patient undergoing therapy for a tumor by determining a residual cancer burden index based on the bidimensional diameters of a primary tumor bed of said tumor in a resection specimen, the proportion of the primary tumor bed area that contains invasive carcinoma, the number of regional lymph nodes containing metastatic carcinoma, the diameter of the largest metastasis in an regional lymph node; and the fractional reduction in lymp…
Patent
Publication NumberCA 2650129 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-13Publication Date2007-10-25
Patent
Publication NumberEP 1759009 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2004-09-30Publication Date2007-03-07
Patent
Publication NumberCA 2569202 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2004-09-30Publication Date2005-12-15
Patent
Publication NumberWO 2005118858 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2004-09-30Publication Date2005-12-15
The present invention provides the identification of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose expression (either increased expression or decreased expression) correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent.
Publication
IDJSTAGE:jbcs.12.2.73Published Date2005-01-01JournalBreast Cancer, 2005-01-01, Volume 12
Individualized selection of the most effective adjuvant (or neoadjuvant) chemotherapy for breast cancer based on the molecular characteristics of the tumor could improve the risk:benefit ratio of current therapies. It could also streamline the development of new regimens for those who are unlikely to benefit from existing drugs. It is expected that combinations of markers will be more informative to predict response than any single gene and may yield regimen-specific predictors. Novel molecul…
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Publications: 1
Patents: 9

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