Publication NumberWO 2019028098 A1
  • Taiga Biotechnologies Inc
StatusPatent Application
Application NumberPCT/US2018/2018044740
Filing Date2018-08-01
Publication Date2019-02-07


Provided herein are methods for adoptive cell transfer for the treatment of cancer, comprising administering a therapeutically effective amount of immune cells having antitumor activity to a subject, wherein the immune cells are contacted with a protein transduction domain (PTD)-MYC fusion polypeptide prior to administration to the subject. In some embodiments, the PTD-MYC fusion polypeptide comprises: (i) an HIV TAT protein transduction domain; and (ii) a MYC polypeptide sequence.


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