47
47
41
41
39
39
49
49
53
53
72
72
92
92
97
97
90
90
105
105
2019
2010
University (1.4K)Research Institution (46)Hospital (26)Company (24)Foundation (15)Investor (4)Other (1)
1 - 10 of 1,401
Sort by
Publication
ID31780386Published Date2020-03-01JournalThe Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2020-03-01, Volume 66
Identification of the temporal pattern of associations between bullying perpetration and mental health problems among youth is needed for the optimal targeting of intervention and prevention. We examined the bidirectional association between bullying perpetration and internalizing problems among youth in the U.S.We used data from the prospective cohort study of the Population Assessment of Tobacco and Health waves 1 (September 12, 2013, to December 14, 2014) and 2 (October 23, 2014, to Octobe…
Publication
ID32030569Published Date2020-02-06JournalBreast cancer research and treatment, 2020-02-06
Selective estrogen receptor degrader (SERD) has proven clinically effective in treating advanced or metastatic breast cancer since the approval of fulvestrant by FDA in 2002. Recent expansion of indications as a first line monotherapy and as combination therapy with CDK4/6 inhibitors further extends its clinical utility as an efficacious breast cancer endocrine regimen. However, the poor pharmacokinetic properties of fulvestrant and its injection-only administration route has driven continued…
Publication
ID32026772Published Date2020-02-05JournalCurrent pharmaceutical design, 2020-02-05
A complex interplay of peripheral and central signaling mechanisms within the body of an organism maintains energy homeostasis. In addition, energy/food intake is modified by various external factors (e.g., palatability, food availability, social and environmental triggers). Highly palatable foods can provoke maladaptive feeding behavior, which in turn disrupts normal homeostatic regulation resulting in numerous health consequences. Furthermore, neuroendocrine peptides, traditionally consider…
Publication
IDDOI:10.1177/0011000019884815Published Date2020-02-01JournalThe Counseling Psychologist, 2020-02-01, Volume 48
The extent to which individuals prioritize different personal values may be conceptually linked to the perceptions of societal stigma associated with seeking psychological help (public stigma), as well as the extent to which they apply that stigma to themselves (self-stigma). We examined how personal values predicted public stigma and self-stigma of seeking psychological help. Undergraduates ( N = 342) from two universities, one historically Black college/university and one predominantly Whit…
Research Grant
Project Number5SC3GM127173-02Funding AgencyNational Institutes of HealthEffective Date2020-02-01Expiration Date2021-01-31Funding Amount$95,850
Summary: Alcohol use disorder (AUD) presents a significant social and economic burden to modern society. Notably, impaired physiological and metabolic status observed in alcoholic patients adversely affects treatment outcome. Furthermore, many alcoholics are malnourished and resultant nutritional deficiencies may contribute to the pathology of alcoholism. However, nutrition is often overlooked as an important treatment component for AUD. Our preliminary data indicate that a patterned feeding …
Publication
ID31952332Published Date2020-01-15JournalMolecules (Basel, Switzerland), 2020-01-15, Volume 25
Zampanolide is a promising microtubule-stabilizing agent (MSA) with a unique chemical structure. It is superior to the current clinically used MSAs due to the covalent nature of its binding to -tubulin and high cytotoxic potency toward multidrug-resistant cancer cells. However, its further development as a viable drug candidate is hindered by its limited availability. More importantly, conversion of its chemically fragile side chain into a stabilized bioisostere is envisioned to enable zampan…
Publication
ID31941053Published Date2020-01-13JournalInternational journal of environmental research and public health, 2020-01-13, Volume 17
The objective of this study was to determine the impact of time spent at work (workload) on the academic performance of pharmacy students. A cross-sectional 12-item survey was administered to pharmacy students at the end of the spring 2011 semester to primarily assess the type of employment and their weekly workload during the 2010-2011 academic year. Academic performance was determined by semester and cumulative grade point average (GPA). Descriptive statistics were performed. Stratified mul…
Publication
ID31956393Published Date2020-01-01JournalComputational and structural biotechnology journal, 2020-01-01, Volume 18
Pathogen-host protein interactions are fundamental for pathogens to manipulate host signaling pathways and subvert host immune defense. For most pathogens, very few or no experimental studies have been conducted to investigate their signaling cross-talks with host. In this study, we propose a computational framework to validate the biological assumption that human protein-protein interaction (PPI) networks alone are sufficient to infer pathogen-host PPIs via pathogen functional mimicry. Patho…
Research Grant
Project Number5U54MD007595-12Funding AgencyNational Institutes of HealthEffective Date2020-01-01Expiration Date2020-12-31Funding Amount$1,301,846
Summary of Research Infrastructure Core The RCMI Cancer Research Center aims to enhance the quality and productivity of Xavier?s basic biomedical and behavior research in the focus area of cancer and cancer-related health disparities by establishing a Research Infrastructure Core (RIC) that will have shared instrumentation, drug discovery and delivery programs, cell and molecular biology facilities, and bioinformatics services. The current core resources build on the previous three RCMI core …
Research Grant
Project Number5U54MD007595-12Funding AgencyNational Institutes of HealthEffective Date2020-01-01Expiration Date2020-12-31Funding Amount$278,967
RCMI Community Engagement Core (CEC) Summary CEC, a Key Component of the Xavier RCMI Center is to facilitate meaningful community involvement to ensure effective and trusted bi-directional relationship between researchers and community. Expanded use of community-based participatory research (CBPR) has been noted as a ?strategic imperative? to develop effective interventions to address health disparities. Community Engagement is an essential component of the research process. A review of the h…
We found 1,401 documents that match your Search
Research Grants: 637
Publications: 726
Patents: 36
Clinical Trials: 2

Wellspring Search is the world's most comprehensive collection of enriched content about emerging and licensable technology innovations.


Already a member? Sign in