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ID32037696Published Date2020-02-09JournalGlobal change biology, 2020-02-09
Species around the world are shifting their ranges in response to climate change. To make robust predictions about climate-related colonizations and extinctions, it is vital to understand the dynamics of range edges. This study is among the first to examine annual dynamics of cold and warm range edges, as most global change studies average observational data over space or over time. We analyzed annual range edge dynamics of marine fishes-both at the individual species level and pooled into co…
Publication
ID32046083Published Date2020-02-07JournalInternational journal of environmental research and public health, 2020-02-07, Volume 17
Extended family can be a resource for conversations about sex, but extended family perspectives have been largely left out of existing research. The present study investigates how extended family, such as aunts and uncles, siblings and cousins, perceive communication with teens in their families about sex. A thematic analysis was conducted with data from interviews in the U.S. with 39 extended family members, primarily siblings, who reported talk with teens in their families about sex. The an…
Publication
ID32032531Published Date2020-02-04JournalMolecular cell, 2020-02-04
Imprinted genes with parental-biased allelic expression are frequently co-regulated and enriched in common biological pathways. Here, we functionally characterize a large cluster of microRNAs (miRNAs) expressed from the maternally inherited allele ("maternally expressed") to explore the molecular and cellular consequences of imprinted miRNA activity. Using an induced neuron (iN) culture system, we show that maternally expressed miRNAs from the miR-379/410 cluster direct the RNA-induced silenc…
Publication
ID31980992Published Date2020-01-24JournalCellular and molecular neurobiology, 2020-01-24
Decapod crustaceans, like mammals, retain the ability to make new neurons throughout life. In mammals, immune cells are closely associated with stem cells that generate adult-born neurons. In crayfish, evidence suggests that immune cells (hemocytes) originating in the immune system travel to neurogenic regions and transform into neural progenitor cells. This nontraditional immune activity takes place continuously under normal physiological conditions, but little is known under pathological co…
Publication
ID31899312Published Date2020-01-23JournalNeuroscience letters, 2020-01-23, Volume 718
In humans and songbirds, neuronal activation for language and song shifts from bilateral- or diffuse-activation to left-hemispheric dominance while proficiency increases. Further parallels exist at the behavioural level: unstructured juvenile vocalizations become highly stereotyped adult vocalizations through a process of trial and error learning. Greater left-hemispheric dominance in the songbird caudomedial Nidopallium (NCM), a Wernicke-like region, is related to better imitation of the tut…
Publication
ID31981678Published Date2020-01-23JournalBrain research, 2020-01-23, Volume 1732
The plasticity that facilitates learning during critical (sensitive) periods in development is tightly regulated by inhibitory neurons. Song acquisition in birds is one example of a learning process that occurs during a sensitive period early in development. Sensory experience with a song 'tutor' during this sensitive period prunes excitatory and inhibitory synapses in the song production nucleus HVC (proper noun). Neurons in the caudomedial nidopallium (NCM), a secondary auditory region, los…
Publication
ID31876422Published Date2020-01-21JournalLangmuir : the ACS journal of surfaces and colloids, 2020-01-21, Volume 36
The bacterial membrane has been suggested as a good target for future antibiotics, so it is important to understand how naturally occurring antibiotics like antimicrobial peptides (AMPs) disrupt those membranes. The interaction of the AMP magainin 2 (MAG2) with the bacterial cell membrane has been well characterized using supported lipid substrates, unilamellar vesicles, and spheroplasts created from bacterial cells. However, to fully understand how MAG2 kills bacteria, we must consider its e…
Publication
IDDOI:10.1177/0192513x19898515Published Date2020-01-20JournalJournal of Family Issues, 2020-01-20
Effective parenting processes during offspring’s adolescence can reduce sexual risk behavior for those offspring in emerging adulthood. Few studies consider how mothers’ and fathers’ parenting processes cluster together and predict emerging adults’ risky sexual behavior. In this study, we used latent profile analysis (LPA) to identify patterns of teens’ perceptions of their residential mothers’ and fathers’ closeness, disapproval of teen sex, monitoring/presence at home, and communication. Us…
Publication
ID31769955Published Date2020-01-13JournalACS combinatorial science, 2020-01-13, Volume 22
Many biotechnological applications require the simultaneous binding of affinity reagents to nonoverlapping target epitopes, the most prominent example being sandwich immunoassays. Typically, affinity pairs are identified via functional analysis of clones that were not selected for complementarity. Here, we developed the Rapid Affinity Pair Identification via Directed Selection (RAPIDS) process, which enables the efficient identification of affinity reagents that function together as complemen…
Publication
ID31839537Published Date2020-01-06JournalDevelopmental cell, 2020-01-06, Volume 52
The propagation of species depends on the ability of germ cells to protect their genome from numerous exogenous and endogenous threats. While these cells employ ubiquitous repair pathways, specialized mechanisms that ensure high-fidelity replication, chromosome segregation, and repair of germ cell genomes remain incompletely understood. We identified Germ Cell Nuclear Acidic Peptidase (GCNA) as a conserved regulator of genome stability in flies, worms, zebrafish, and human germ cell tumors. G…
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Publications: 1,776
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