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ID31743442Published Date2020-06-15JournalThe Journal of comparative neurology, 2020-06-15, Volume 528
Two decades after the discovery of adult-born neurons in the brains of decapod crustaceans, the deutocerebral proliferative system (DPS) producing these neural lineages has become a model of adult neurogenesis in invertebrates. Studies on crayfish have provided substantial insights into the anatomy, cellular dynamics, and regulation of the DPS. Contrary to traditional thinking, recent evidence suggests that the neurogenic niche in the crayfish DPS lacks self-renewing stem cells, its cell pool…
Publication
ID32341163Published Date2020-05-12JournalProceedings of the National Academy of Sciences of the United States of America, 2020-05-12, Volume 117
People evaluate a stranger's trustworthiness from their facial features in a fraction of a second, despite common advice "not to judge a book by its cover." Evaluations of trustworthiness have critical and widespread social impact, predicting financial lending, mate selection, and even criminal justice outcomes. Consequently, understanding how people perceive trustworthiness from faces has been a major focus of scientific inquiry, and detailed models explain how consensus impressions of trust…
Publication
IDDOI:10.1093/qmathj/haaa005Published Date2020-05-08JournalThe Quarterly Journal of Mathematics, 2020-05-08
Abstract We use rational formality of configuration spaces and the bar construction to study the cohomology of the space of braids in dimension four or greater. We provide a diagram complex for braids and a quasi-isomorphism to the de Rham cochains on the space of braids. The quasi-isomorphism is given by a configuration space integral followed by Chen’s iterated integrals. This extends results of Kohno and of Cohen and Gitler on the cohomology of the space of braids to a commutative differen…
Publication
ID32402986Published Date2020-05-06JournalInternational journal of medical informatics, 2020-05-06, Volume 139
Identify opportunities to improve the interaction between clinicians and Tele-Critical Care (Tele-CC) programs through an analysis of alert occurrence and reactivation in a specific Tele-CC application.Data were collected automatically through the Philips eCaremanager® software system used at multiple hospitals in the Avera health system. We evaluated the distribution of alerts per patient, frequency of alert types, time between consecutive alerts, and Tele-CC clinician choice of alert reacti…
Publication
ID32037696Published Date2020-05-01JournalGlobal change biology, 2020-05-01, Volume 26
Species around the world are shifting their ranges in response to climate change. To make robust predictions about climate-related colonizations and extinctions, it is vital to understand the dynamics of range edges. This study is among the first to examine annual dynamics of cold and warm range edges, as most global change studies average observational data over space or over time. We analyzed annual range edge dynamics of marine fishes-both at the individual species level and pooled into co…
Publication
IDDOI:10.1162/rest_a_00824Published Date2020-05-01JournalThe Review of Economics and Statistics, 2020-05-01, Volume 102
We estimate the causal effects of education on the intergenerational transmission of violence against children by exploiting an extension of compulsory schooling in Turkey. Using a regression-discontinuity design, we find that the reform increased maternal education by one year, with stronger effects for women raised in rural areas. The increase in education among rural women led to a reduction in the perpetration of child physical abuse but only by mothers who were physically abused by their…
Publication
ID32344834Published Date2020-04-25JournalViruses, 2020-04-25, Volume 12
Retroviral nucleocapsid (NC) proteins are nucleic acid chaperones that play distinct roles in the viral life cycle. During reverse transcription, HIV-1 NC facilitates the rearrangement of nucleic acid secondary structures, allowing the transactivation response (TAR) RNA hairpin to be transiently destabilized and annealed to a complementary RNA hairpin. In contrast, during viral assembly, NC, as a domain of the group-specific antigen (Gag) polyprotein, binds the genomic RNA and facilitates pac…
Publication
ID32266720Published Date2020-04-07JournalJournal of anatomy, 2020-04-07
Dentine- and enamel-forming cells secrete matrix in consistent rhythmic phases, resulting in the formation of successive microscopic growth lines inside tooth crowns and roots. Experimental studies of various mammals have proven that these lines are laid down in subdaily, daily (circadian), and multidaily rhythms, but it is less clear how these rhythms are initiated and maintained. In 2001, researchers reported that lesioning the so-called master biological clock, the suprachiasmatic nucleus …
Publication
ID32032531Published Date2020-04-02JournalMolecular cell, 2020-04-02, Volume 78
Imprinted genes with parental-biased allelic expression are frequently co-regulated and enriched in common biological pathways. Here, we functionally characterize a large cluster of microRNAs (miRNAs) expressed from the maternally inherited allele ("maternally expressed") to explore the molecular and cellular consequences of imprinted miRNA activity. Using an induced neuron (iN) culture system, we show that maternally expressed miRNAs from the miR-379/410 cluster direct the RNA-induced silenc…
Publication
ID32061770Published Date2020-04-01JournalInsect biochemistry and molecular biology, 2020-04-01, Volume 119
Life history trade-offs lead to various strategies that maximize fitness, but the developmental mechanisms underlying these alternative strategies continue to be poorly understood. In insects, trade-offs exist between size and developmental time. Recent studies in the fruit fly Drosophila melanogaster have suggested that the steroidogenic prothoracic glands play a key role in determining the timing of metamorphosis. In this study, the nutrient-dependent growth and transcriptional activation o…
We found 2,395 documents that match your Search
Research Grants: 502
Publications: 1,863
Patents: 26
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