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University (27.9K)Research Institution (1.6K)Company (395)Hospital (302)Foundation (234)Other (161)Investor (4)
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Publication
ID31970267Published Date2020-06-01JournalRegenerative therapy, 2020-06-01, Volume 14
Inflammatory bowel disease (IBD) is an intractable condition. Existing models of experimental IBD are limited by their inability to create consistent ulcers between animals. The aim of this study was to develop a novel model of experimental colitis with ulcers of reproducible size.We used a 3D printer to fabricate a novel device containing a small window (10 × 10 mm) that could be inserted rectally to facilitate the creation of a localized ulcer in the rat intestinal mucosa. The mucosa within…
Publication
ID32089434Published Date2020-06-01JournalJournal of bioscience and bioengineering, 2020-06-01, Volume 129
In Japan, the imports of meat products have been increasing every year. Heat processing of meat is the current standard method for ensuring domestic animal health, particularly in case of meat products from areas where infectious diseases are known to have occurred in domestic animals. The Animal Quarantine Service needs to establish a method that detects the temperature at which the meat has been heat-processed (endpoint temperature) to ensure that the standard protocol is followed at the pr…
Publication
ID32291491Published Date2020-06-01JournalApplied microbiology and biotechnology, 2020-06-01, Volume 104
Hydroxyproline is an industrially important compound with applications in the pharmaceutical, nutrition, and cosmetic industries. trans-4-Hydroxy-L-proline is recognized as the most abundant of the eight possible isomers (hydroxy group at C-3 or C-4, cis- or trans-configuration, and L- or D-form). However, little attention has been paid to the rare isomers, probably due to their limited availability. This mini-review provides an overview of recent advances in microbial and enzymatic processes…
Publication
ID32156571Published Date2020-06-01JournalBrain research, 2020-06-01, Volume 1736
Proper migration and positioning of Purkinje cells are important for formation of the developing cerebellum. Although several cyclin-dependent kinase 5 (Cdk5) substrates are known to be critical for ordered neuronal migration, there are no reports of mutant mouse-based, in vivo studies on the function of Cdk5-phosphorylation substrates in migration of Purkinje cells. We focused on the analysis of collapsin response mediator protein 2 (CRMP2), one of the Cdk5 substrates, because a previous stu…
Publication
ID32046625Published Date2020-06-01JournalBioscience, biotechnology, and biochemistry, 2020-06-01, Volume 84
Lysosome is the principal organelle for the ultimate degradation of cellular macromolecules, which are delivered through endocytosis, phagocytosis, and autophagy. The lysosomal functions have been found to be impaired by fatty foods and aging, and more importantly, the lysosomal dysfunction in macrophages has been reported as a risk of atherosclerosis development. In this study, we searched for dietary polyphenols which possess the activity for enhancing the lysosomal degradation in J774.1, a…
Publication
IDIEEE:9001187Published Date2020-06-01JournalIEEE Transactions on Applied Superconductivity, 2020-06-01, Volume 30
The no-insulation (NI) coil is a technology expected to realize both high current density and high thermal stability which are essentially trade-off relationship in REBCO coil application. This technique has been studied mainly for application to small-diameter inner coils of NMR magnets exceeding 30 T. In this case, the coil is cooled using 4.2-K liquid He. We are developing an NI-REBCO coil system for high-magnetic-field whole-body MRI, and for a medical cyclotron to be used for cancer ther…
Publication
ID31691039Published Date2020-06-01JournalJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2020-06-01, Volume 23
We examined typical commercial poly(ethersulfone) (PESf) hemodialysis and hemoconcentration membranes successfully used in manufacturing, and employed scanning probe microscope (SPM) to achieve a structural observation of the pores in the inner membrane surfaces, as well as measure the pore diameters and their distribution, verifying the relationship between the typical mass transfer properties. We focused on the differences between the PESf membranes which were expected to further improve th…
Publication
ID31988998Published Date2020-06-01JournalRegenerative therapy, 2020-06-01, Volume 14
Cultured stratified epithelial cell sheets have been clinically utilized as transplantable grafts for the regeneration of epithelial tissues, such as the esophagus, cornea, skin, and intraoral cavity. These cell sheets are expected to gain widespread use as regenerative medicine products and save many patients. For this purpose, establishing and disseminating the stale protocol of fabricating the cell sheet is crucial. The fabrication of cultured stratified epithelial cell sheets consists of …
Publication
ID32432844Published Date2020-06-01JournalMedicine and science in sports and exercise, 2020-06-01, Volume 52
Interoception is a sense of the physiological state of one's body. Interoception that is generated by processing physiological information in the insular cortex plays an important role in achieving optimal performance in competitive sports. This study aimed to reveal the difference in interoceptive ability between long-distance runners and sprinters and its neural correlates by recording the stimulus-preceding negativity (SPN) that is generated from the insular cortex. Based on previous findi…
Publication
ID31975032Published Date2020-06-01JournalCell and tissue research, 2020-06-01, Volume 380
Cell migration is essential for many physiological and pathological processes, including embryonic development, wound healing, immune response and cancer metastasis. Inka2 transcripts are observed in migrating cells during embryonic development, suggesting the involvement of inka2 in cell migration. However, its precise role remains unclear. Here, we found that inka2 controlled focal adhesion dynamics and cell migration, likely by regulating protein phosphatase-2A (PP2A) function. A scratch a…
We found 27,913 documents that match your Search
Research Grants: 50
Publications: 26,129
Patents: 313
Clinical Trials: 103
Web Documents: 1,318

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