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Research Institution (49.2K)University (49.2K)Hospital (3.3K)Company (1.3K)Foundation (660)Investor (138)Other (97)
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Clinical Trial
Clinical Trial IDNCT04105985Start Date2020-04-01Completion Date2021-05-01PhasePhase 2Study TypeInterventionalStatusSuspended
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
Publication
ID30615588Published Date2020-04-01JournalJournal of American college health : J of ACH, 2020-04-01, Volume 68
The present study evaluated the prevalence of past suicidal ideation (SI), plan, and attempt in college students with ADHD ( = 102) compared to a matched control ( = 102). Predictors of SI, plan, and attempts, were examined. Study participants were first year college students at a large Southeastern university who completed measures during August or September of 2014 or January of 2015. Measures were completed by first year students via an online survey. Prevalence rates for SI and related be…
Publication
ID31313819Published Date2020-04-01JournalNeurosurgery, 2020-04-01, Volume 86
Recent randomized control trials (RCTs) established that mechanical thrombectomy is superior to medical therapy for patients with stroke due to a large vessel occlusion.To compare the safety and efficacy profile of the different mechanical thrombectomy strategies.A random-effects meta-analysis was performed and the I2 statistic was used to assess heterogeneity according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.Nineteen studies with a total …
Publication
ID31917153Published Date2020-04-01JournalNeuropharmacology, 2020-04-01, Volume 166
Neuropathy is major source of chronic pain that can be caused by mechanically or chemically induced nerve injury. Intraplantar formalin injection produces local necrosis over a two-week period and has been used to model neuropathy in rats. To determine whether neuropathy alters dopamine (DA) receptor responsiveness in mesolimbic brain regions, we examined dopamine D-like and D-like receptor (DR) signaling and expression in male rats 14 days after bilateral intraplantar formalin injections int…
Clinical Trial
Clinical Trial IDNCT03931252Start Date2020-04-01Completion Date2021-03-01PhaseN/AStudy TypeInterventionalStatusEnrolling by invitation
The investigators propose to assess the contributions of the thermic effect of food intake (TEF), which is the amount of energy expended to digest food, to overall energy expenditure in Cystic Fibrosis (CF).
Clinical Trial
Clinical Trial IDNCT04104789Start Date2020-04-01Completion Date2021-05-01PhasePhase 2Study TypeInterventionalStatusSuspended
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
Publication
ID30371748Published Date2020-04-01JournalBiostatistics (Oxford, England), 2020-04-01, Volume 21
Epidemiological studies on periodontal disease (PD) collect relevant bio-markers, such as the clinical attachment level (CAL) and the probed pocket depth (PPD), at pre-specified tooth sites clustered within a subject's mouth, along with various other demographic and biological risk factors. Routine cross-sectional evaluation are conducted under a linear mixed model (LMM) framework with underlying normality assumptions on the random terms. However, a careful investigation reveals considerable …
Publication
ID31765502Published Date2020-04-01JournalJournal of clinical pharmacy and therapeutics, 2020-04-01, Volume 45
WHAT IS KNOWN AND OBJECTIVE?: Antiretroviral (ARV) resistance may result during periods of consistently poor adherence. We report the successful use of a novel once-daily (QD) ARV regimen in a patient with multidrug-resistant (MDR) HIV. CASE SUMMARY: Once-daily darunavir 1200 mg/ritonavir 100 mg, dolutegravir and emtricitabine/tenofovir alafenamide was initiated with directly observed therapy. With the assistance of therapeutic drug monitoring, dolutegravir dosing was increased to 150 mg dail…
Publication
ID32168026Published Date2020-04-01JournalBehavioural pharmacology, 2020-04-01, Volume 31
Pain management is a challenging and unmet medical need. Despite their demonstrated efficacy, currently used opioid drugs and nonsteroidal anti-inflammatory drugs are frequently associated with several adverse events. The identification of new and safe analgesics is therefore needed. MP1104, an analogue of 3'-iodobenzoyl naltrexamine, is a potent nonselective full agonist at mu (MOR), kappa (KOR), and delta (DOR) opioid receptors, respectively. It was shown to possess potent antinociceptive e…
Publication
ID31342795Published Date2020-04-01JournalClinical toxicology (Philadelphia, Pa.), 2020-04-01, Volume 58
Copperhead snakes () are considered as the least toxic of the North American pit vipers. The reported incidence of coagulopathy from copperhead envenomation is variable, possibly secondary to regional variation in subspecies and venom potency. Coagulation studies are often obtained when evaluating for the coagulopathic effects of copperhead venom, but the clinical utility of these indices is unclear. The aim of this study was to determine the prevalence of hematologic toxicity due to copperhe…
We found 49,282 documents that match your Search
Research Grants: 12,078
Publications: 34,115
Patents: 1,379
Clinical Trials: 1,475
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