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ID32200717Published Date2020-04-07JournalJournal of the American Heart Association, 2020-04-07, Volume 9
Background Moderate alcohol consumption has been associated with a lower risk of cardiovascular disease (CVD) and all-cause mortality compared with heavy drinkers and abstainers. To date, studies have relied on self-reported consumption, which may be prone to misclassification. Urinary ethyl glucuronide (EtG) is an alcohol metabolite and validated biomarker for recent alcohol consumption. We aimed to examine and compare the associations of self-reported alcohol consumption and EtG with CVD an…
Publication
IDDOI:10.1161/jaha.119.014324Published Date2020-04-07JournalJournal of the American Heart Association, 2020-04-07, Volume 9
Background Moderate alcohol consumption has been associated with a lower risk of cardiovascular disease (CVD) and all‐cause mortality compared with heavy drinkers and abstainers. To date, studies have relied on self‐reported consumption, which may be prone to misclassification. Urinary ethyl glucuronide (EtG) is an alcohol metabolite and validated biomarker for recent alcohol consumption. We aimed to examine and compare the associations of self‐reported alcohol consumption and EtG with CVD an…
Publication
ID31931203Published Date2020-04-10JournalThe Science of the total environment, 2020-04-10, Volume 712
Debris flows are one of the most hazardous types of landslides in mountain regions. In the upper part of the Zêzere valley (Serra da Estrela, Portugal) several debris flows events occurred in the last 200 years, some of them causing loss of lives and material damages. In this work, a methodology for pedestrian evacuation modelling, in a debris flow hazard scenario, was implemented. A dynamic run-out model, developed in previous studies, was used to evaluate the debris flows velocities, thickn…
Publication
ID32050402Published Date2020-04-10JournalThe Science of the total environment, 2020-04-10, Volume 712
Although the consideration of socio-economic demands with biodiversity conservation is now high on the environmental policy agenda, it is not yet standard practice in spatial planning. This is argued to be related, among others, to a lack of awareness among stakeholders and practitioners of the underpinning role of ecosystem functioning and biodiversity to support human well-being. Meanwhile, there is mounting critique on the absolute focus of biodiversity conservation on static properties su…
Publication
IDDOI:10.1083/jcb.201907149Published Date2020-04-06JournalJournal of Cell Biology, 2020-04-06, Volume 219
Cellular functioning relies on active transport of organelles by molecular motors. To explore how intracellular organelle distributions affect cellular functions, several optogenetic approaches enable organelle repositioning through light-inducible recruitment of motors to specific organelles. Nonetheless, robust application of these methods in cellular populations without side effects has remained challenging. Here, we introduce an improved toolbox for optogenetic control of intracellular tr…
Publication
ID31982580Published Date2020-04-15JournalNeuroImage, 2020-04-15, Volume 210
Microvascular blood volume pulsations due to the cardiac and respiratory cycles induce brain tissue deformation and, as such, are considered to drive the brain's waste clearance system. We have developed a high-field magnetic resonance imaging (MRI) technique to quantify both cardiac and respiration-induced tissue deformations, which could not be assessed noninvasively before. The technique acquires motion encoded snapshot images in which various forms of motion and confounders are entangled.…
Publication
ID32006816Published Date2020-04-15JournalJournal of colloid and interface science, 2020-04-15, Volume 566
Assembly of plasmonic nanoparticle clusters having hotspots in a specific space is an effective way to efficiently utilize their plasmonic properties. In the assembly, however, bulk-like aggregates of the nanoparticles are readily formed by strong van der Waals forces, inducing a decrease of the properties. The present work proposes an advanced method to avoid aggregation of the clusters by encapsulating into a confined space of hollow silica interior. Hollow spheres incorporating gold nanopa…
Publication
ID31917752Published Date2020-04-15JournalJournal of acquired immune deficiency syndromes (1999), 2020-04-15, Volume 83
Interventions aiming for an HIV cure would benefit from rapid elimination of virus after the onset of antiretroviral therapy (ART), by keeping the latent HIV reservoir small.We investigated HIV suppression in 312 perinatally infected infants starting ART within 6 months after birth from the EPPICC (European Pregnancy and Paediatric HIV Cohort Collaboration).To better understand kinetic differences in HIV suppression among infants, we investigated their individual viral load (VL) decay dynamic…
Publication
ID32145852Published Date2020-04-15JournalAnalytica chimica acta, 2020-04-15, Volume 1106
Analytical capabilities of Nanoscopic Secondary Ion Mass Spectrometry (nano-SIMS) and Synchrotron Radiation based X-ray Fluorescence (SR nano-XRF) techniques were compared for nanochemical imaging of polymorphonuclear human neutrophils (PMNs). PMNs were high pressure frozen (HPF), cryo-substituted, embedded in Spurr's resin and cut in thin sections (500 nm and 2 μm for both techniques resp.) Nano-SIMS enabled nanoscale mapping of isotopes of C, N, O, P and S, while SR based nano-XRF enabled t…
Publication
ID31864791Published Date2020-04-15JournalInternational journal of cardiology, 2020-04-15, Volume 305
Evidence suggests that the burden of peripheral artery disease (PAD) is rising more rapidly than other forms of cardiovascular diseases in sub-Saharan Africa, but the extent to which they differ between rural and urban settings in Africa and upon migration to Europe is unknown. We assessed the burden of PAD among Ghanaians living in rural- and urban-Ghana and Ghanaian migrants living in three European countries.Cross-sectional analyses of baseline data from the multicenter Research on Obesity…
We found 61,176 documents that match your Search
Research Grants: 1,496
Publications: 58,445
Patents: 293
Clinical Trials: 941
Web Documents: 1

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