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Publication
ID31972944Published Date2020-02-25JournalThe Science of the total environment, 2020-02-25, Volume 705
To date, the effect of household airborne pollutants on the association between airborne endotoxin and lung function of schoolchildren is unknown.The objective of this study is to evaluate whether indoor air pollutants such as carbon monoxide (CO), carbon dioxide (CO), nitrogen dioxide (NO), sulfur dioxide (SO), ozone (O), particulate matter with aerodynamic diameter
Publication
ID31809265Published Date2020-02-25JournalJournal of pediatric endocrinology & metabolism : JPEM, 2020-02-25, Volume 33
Background Non-adherence to diabetes medication leads to poor outcomes and increased healthcare costs. Multiple factors affecting adherence in adults with type 2 diabetes (T2D) have been identified, but pediatric data is sparse. We aimed to determine whether initiation of additional oral medications or insulin affects adherence to primary study medication (PSM) in the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) study. Methods Six hundred and ninety-nine youth (aged …
Publication
ID32020839Published Date2020-02-18JournalJournal of the American Heart Association, 2020-02-18, Volume 9
Background De novo lipogenesis (DNL) is an endogenous pathway that converts excess dietary starch, sugar, protein, and alcohol into specific fatty acids (FAs). Although elevated DNL is linked to several metabolic abnormalities, little is known about how long-term habitual levels and changes in levels of FAs in the DNL pathway relate to incident heart failure (HF). Methods and Results We investigated whether habitual levels and changes in serial measures of FAs in the DNL pathway were associat…
Publication
ID32021757Published Date2020-03-01JournalPreventive medicine reports, 2020-03-01, Volume 17
Ensuring young children have adequate opportunities for physical activity (PA) is important, and policies at childcare centers may help to ensure children have adequate opportunities. The purpose of this study is to examine the associations between center policies and odds of meeting best practices for PA in non-Head Start Texas early care and education (ECE) centers. Licensed centers with publicly available email addresses on the Texas Department of Family and Protective Services website wer…
Publication
ID31733304Published Date2020-03-01JournalMicrovascular research, 2020-03-01, Volume 128
Blood brain barrier (BBB) permeability and oxidative stress have been reported to be important mechanisms for brain damage following ischemic stroke and stanniocalcin-1 (STC-1), a neuroprotective protein, has anti-inflammatory and anti-oxidative stress properties. Herein, we report the effect of STC-1 on BBB permeability and brain oxidative stress after stroke in an animal model. Male Wistar received an intracerebroventricularly injection of human recombinant STC-1 (100 ng/kg) or saline and w…
Publication
ID31890987Published Date2020-03-01JournalContemporary clinical trials communications, 2020-03-01, Volume 17
Although there are a number of effective treatments for posttraumatic stress disorder (PTSD), there is a need to develop more efficient evidence-based PTSD treatments to address barriers to seeking and receiving treatment. Written exposure therapy (WET) is a potential alternative that is a 5-session treatment without any between-session assignments. WET has demonstrated efficacy, and low treatment dropout rates. However, prior studies with WET have primarily focused on civilian samples. Ident…
Clinical Trial
Clinical Trial IDNCT04207359Start Date2020-03-01Completion Date2021-03-01PhasePhase 1Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to test the hypothesis that creatine will accelerate adaptations associated with exercise in breast cancer survivors recently completing chemotherapy.
Clinical Trial
Clinical Trial IDNCT04200911Start Date2020-03-01Completion Date2022-03-01PhaseEarly Phase 1Study TypeInterventionalStatusNot yet recruiting
Evaluation of central nervous system penetration of orally administered Rapamune (RAPA) in older adults with Mild Cognitive Impairment (MCI) or early Alzheimer's disease (AD) and investigate associated safety, tolerability, target engagement, cognition, and functional status as initial proof-of-concept study
Publication
ID31183797Published Date2020-03-01JournalSurgical endoscopy, 2020-03-01, Volume 34
Patients with obesity have a higher risk of trocar site hernia. The objective of the present study was to compare a standard suture passer versus the neoClose device for port site fascial closure in patients with obesity undergoing laparoscopic bariatric surgery.This is a randomized, controlled trial with two parallel arms. Thirty five patients with BMI ≥ 35 kg/m and undergoing laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass were randomized to each group. Port site fascial closure…
Publication
ID31485931Published Date2020-03-01JournalSurgical endoscopy, 2020-03-01, Volume 34
After careful review, the authors have noticed the following mistakes in the article entitled "Trocar site closure with a novel anchor based (neoClose®) system versus standard suture closure: A prospective randomized controlled trial": - Correct closure times are 19.9 seconds (SD 9.9) for the study group and 31.0 seconds (SD 20.1) for the control group (initial incorrect values were 20.2 seconds (SD 10.1) and 30 seconds (SD 19.1) respectively). The new correct P-value is
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