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Clinical Trial
Clinical Trial IDNCT04222270Start Date2020-04-01Completion Date2021-11-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Adherence for children living with HIV is a by-proxy phenomenon dependent on caregivers (parents, relatives or unrelated guardians) who may or may not be living with HIV. The complexity of paediatric formulations and dosing for ART regimens often poses challenges for caregivers, making ART administration and achievement of viral suppression quite a difficult task for young children. Peer support for caregivers presents a potentially feasible and impactful approach to improve ART adherence and…
Publication
ID31679454Published Date2020-04-01JournalAutophagy, 2020-04-01, Volume 16
Macroautophagy (which we will call autophagy hereafter) is a critical intracellular bulk degradation system that is active at basal rates in eukaryotic cells. This process is embedded in the homeostasis of nutrient availability and cellular metabolic demands, degrading primarily long-lived proteins and specific organelles.. Autophagy is perturbed in many pathologies, and its manipulation to enhance or inhibit this pathway therapeutically has received considerable attention. Although better pr…
Clinical Trial
Clinical Trial IDNCT04151602Start Date2020-04-01Completion Date2024-04-01Study TypeObservationalStatusNot yet recruiting
Tuberculosis (TB) is the leading infectious disease killer globally and leading cause of death in persons with HIV. The most effective way to reduce TB incidence and mortality is to interrupt transmission. This requires finding and treating individuals with TB disease early, including those with subclinical disease. Molecular epidemiologic studies and mathematical models have shown that the primary approach to case finding—household contact tracing—identifies only 8-19% of transmissions in hi…
Research Grant
ReferenceAH/T008199/1Funding AgencyUnited Kingdom Research and InnovationEffective Date2020-03-31Expiration Date2024-03-31Funding Amount$2,335,662
Archives are sites of negotiation about visions of the future. Decisions of what is to be collected, accessed or preserved tend to privilege certain narratives over others. It is about whose story will continue to be told and how, and whose silenced. These questions are acute in moments of post-conflict, displacement and reconstruction. Our Network depends on linking expertise from contexts where these issues are paramount: in Lebanon, Tanzania, Ghana, South Africa, and if possible Syria. The…
Publication
ID32200897Published Date2020-04-22JournalAnalytica chimica acta, 2020-04-22, Volume 1107
Thermal field-flow fractionation (ThFFF) was successfully coupled online to size exclusion chromatography (SEC) in a comprehensive two-dimensional configuration. In the first dimension, fractionation according to chemical composition based on the interplay of thermal and translational diffusion took place in the ThFFF channel. Fractions from the first dimension were comprehensively transferred to the second dimension, SEC, and separated according to hydrodynamic volume which is a function of …
Publication
IDDOI:10.17159/sajs.2020/6772/supplPublished Date2020-03-26JournalSouth African Journal of Science, 2020-03-26, Volume 116
The gender pay gap – that is, the difference in wages between men and women for the same or substantially the same work, or work of equal value – still features prominently as a stumbling block in achieving South African gender equality. If South Africa is to dislodge its stagnant gender pay gap, especially for women in the middle and upper levels of the wage distribution, pay transparency – making gender differences in wages known to employees, government and the public – can compel employer…
Patent
Publication NumberUS 20200095592Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-05-30Publication Date2020-03-26
The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting str…
Publication
IDDOI:10.17159/sajs.2020/6772Published Date2020-03-26JournalSouth African Journal of Science, 2020-03-26, Volume 116
The gender pay gap – that is, the difference in wages between men and women for the same or substantially the same work, or work of equal value – still features prominently as a stumbling block in achieving South African gender equality. If South Africa is to dislodge its stagnant gender pay gap, especially for women in the middle and upper levels of the wage distribution, pay transparency – making gender differences in wages known to employees, government and the public – can compel employer…
Publication
ID32195502Published Date2020-03-20JournalFood & function, 2020-03-20
Mounting evidence of the ability of aspalathin to target underlying metabolic dysfunction relevant to the development or progression of obesity and type 2 diabetes created a market for green rooibos extract as a functional food ingredient. Aspalathin is the obvious choice as a chemical marker for extract standardisation and quality control, however, often the concentration of a single constituent of a complex mixture such as a plant extract is not directly related to its bio-capacity, i.e. th…
Publication
ID32191238Published Date2020-03-19JournalChemical communications (Cambridge, England), 2020-03-19
Flexible and transformable molecules, particularly those responding to external stimuli, are needed for designing sensors and porous compounds capable of storing or separating gases and liquids. Under normal conditions the photochromic compound, 1,2-bis[2-methyl-5-(pyridyl)-3thienyl]cyclopentene (BTCP) forms a porous co-crystal with 1,4-diiodotetrafluorobenzene (dItFB). It traps acetone (Ac) molecules in the pores. Owing to a unique system of pores in the polar framework, the crystal is sensi…
We found 7,080 documents that match your Search
Research Grants: 284
Publications: 6,526
Patents: 171
Clinical Trials: 98
Web Documents: 1

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