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ID31617551Published Date2019-11-14JournalPhysical chemistry chemical physics : PCCP, 2019-11-14, Volume 21
YIV-906 (formally PHY906, KD018) is a four-herb formulation that is currently being developed to improve the therapeutic index and ameliorate the side effects of many chemotherapeutic drugs including sorafenib, irinotecan, and capecitabine. However, as a promising anti-cancer adjuvant, the molecular mechanism of action of YIV-906 remains unrevealed due to its multi-component and multi-target features. Since YIV-906 has been shown to induce apoptosis and autophagy in cancer cells through modul…
Publication
ID31603452Published Date2019-11-14JournalJournal of materials chemistry. B, 2019-11-14, Volume 7
Correction for 'One-step synthesis of a dual-emitting carbon dot-based ratiometric fluorescent probe for the visual assay of Pb and PPi and development of a paper sensor' by Yifang Gao et al., J. Mater. Chem. B, 2019, 7, 5502-5509.
Publication
ID31466212Published Date2019-11-15JournalThe Science of the total environment, 2019-11-15, Volume 691
Frameworks for limiting ecosystem exposure to excess nutrients and acidity require accurate and complete deposition budgets of reactive nitrogen (Nr). While much progress has been made in developing total Nr deposition budgets for the U.S., current budgets remain limited by key data and knowledge gaps. Analysis of National Atmospheric Deposition Program Total Deposition (NADP/TDep) data illustrates several aspects of current Nr deposition that motivate additional research. Averaged across the…
Publication
ID31472253Published Date2019-11-15JournalNeuroImage, 2019-11-15, Volume 202
Diffusion MRI tractography has been used to map the axonal structure of the human brain, but its ability to detect neuronal injury is yet to be explored. Here we report differential tractography, a new type of tractography that utilizes repeat MRI scans and a novel tracking strategy to map the exact segment of fiber pathways with a neuronal injury. We examined differential tractography on multiple sclerosis, Huntington's disease, amyotrophic lateral sclerosis, and epileptic patients. The resu…
Publication
ID31210093Published Date2019-11-15JournalJournal of neurotrauma, 2019-11-15, Volume 36
Favorable long-term functional outcomes after severe traumatic brain injury (TBI) may be underestimated. We analyzed 24-month functional outcomes from a consecutive series of severe TBI survivors. A prospective, observational database of severe TBI survivors from a single institution was analyzed. Glasgow Outcome Scale-Extended (GOS-E) scores were obtained at 3, 6, 12, and 24 months post-injury. GOS-E scores were dichotomized into unfavorable and favorable outcomes, and the proportion of surv…
Publication
ID31465844Published Date2019-11-15JournalNeuroImage, 2019-11-15, Volume 202
Early life factors may influence brain and academic outcomes later in life, especially during childhood. Here we investigate the associations of early life factors (i.e., birth weight, birth length, and breastfeeding) with gray matter volume, adjusted for body mass index and cardiorespiratory fitness, and ii) we test whether early-life factor-related differences in gray matter volume are associated with academic performance in overweight/obese children. 96 children with overweight/obesity age…
Publication
ID31408030Published Date2019-11-15JournalAIDS (London, England), 2019-11-15, Volume 33
Assessment of safety is an integral part of real-time monitoring in clinical trials. In HIV prevention research, safety of investigational products and trial participation has been expanded to include monitoring for 'social harms', generally defined as negative consequences of trial participation that may manifest in social, psychological, or physical ways. Further research on social harms within HIV prevention research is needed to understand the potential safety risks for women and advance …
Publication
ID31326795Published Date2019-11-15JournalThe Science of the total environment, 2019-11-15, Volume 691
For the first time in the 40-year history of the National Atmospheric Deposition Program/National Trends Network (NADP/NTN), a unique urban-to-rural transect of wet deposition monitoring stations was operated as part of the NTN in 2017 to quantify reactive inorganic nitrogen wet deposition for adjacent urban and rural, montane regions. The transect of NADP stations (sites) was used to collect continuous precipitation depth and weekly wet-deposition samples in the Denver - Boulder, Colorado, u…
Publication
ID31408717Published Date2019-11-15JournalNeuroImage, 2019-11-15, Volume 202
F-MR imaging of perfluorocarbon (PFC)-labeled macrophages can provide a unique insight into their participation and spatio-temporal dynamics of inflammatory events, such as the biodegradation of an extracellular matrix (ECM) hydrogel implanted into a stroke cavity. To determine the most efficient acquisition strategy for F-MR imaging, five commonly used sequences were optimized using a design of experiment (DoE) approach and compared based on their signal-to-noise ratio (SNR). The fast imagin…
Publication
ID31462565Published Date2019-11-15JournalJournal of virology, 2019-11-15, Volume 93
We present the genome sequences of tailed phages Sasha, Sergei, and Solent. These phages, along with phages 9NA, FSL_SP-062, and FSL_SP-069 and the more distantly related phage PmiS-Isfahan, have similarly sized genomes of between 52 and 57 kbp in length that are largely syntenic. Their genomes also show substantial genome mosaicism relative to one another, which is common within tailed phage clusters. Their gene content ranges from 80 to 99 predicted genes, of which 40 are common to all seve…
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