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Patent
Publication NumberUS 20200095609Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-12-09Publication Date2020-03-26
The present invention relates to a gene therapy vector which is useful in the treatment or prevention of hypertrophic cardiomyopathy in a subject in need thereof. The gene therapy vector of the invention comprises a nucleic acid sequence encoding a cardiac sarcomeric protein and a cardiomyocyte-specific promoter which is operably linked to said nucleic acid sequence. The invention furthermore relates to a cell which comprises the gene therapy vector. Pharmaceutical compositions which comprise…
Patent
Publication NumberUS 10596297Filing StatusIssued PatentAvailabilityUnknownFiling Date2014-10-01Publication Date2020-03-24
The present invention relates to a method for preparing a fibrillar collagen matrix, which is advantageously transparent or composite, suitable for being used as a biomaterial, in particular as a corneal substitute.
Publication
ID32205302Published Date2020-03-20JournalJournal of stomatology, oral and maxillofacial surgery, 2020-03-20
Surgical revision rate of rhinoplasty is from 5% to 15% in literature.In the context of post-rhinoplasty deformities, we aim to investigate the modalities of using injectables, their impacts on revision rate of rhinoplasty as well as their influences on the surgical strategy.We realized an international literature review to collect informations on main studies reporting series of exclusive secondary medical rhinoplasties or mixed primary/secondary medical rhinoplasties, as well as per-operati…
Patent
Publication NumberUS 10590420Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-07-31Publication Date2020-03-17
The invention relates to a method for the treatment of amyotrophic lateral sclerosis (ALS). Specifically, the invention implements the use of an antisense sequence adapted to affect alternative splicing in a human SOD1 pre-mRNA, thereby leading to the destruction of the skipped m RNA by the cell machinery.
Patent
Publication NumberUS 10582977Filing StatusIssued PatentAvailabilityUnknownFiling Date2016-02-05Publication Date2020-03-10
The invention relates to a device and a method to assist with the operation of an instrument by means of said device, the device and the method using leverage effects in order to calculate the data relative to any point of an instrument axis, instead of using low-accuracy sensors. Other improvements are also described that allow higher-quality usage performance for the operator, which reduces the risk of errors and simplifies the operations.
Patent
Publication NumberUS 10578619Filing StatusIssued PatentAvailabilityUnknownFiling Date2014-07-30Publication Date2020-03-03
The present invention relates to methods and kits for identifying effector regulatory T cells. In particular the present invention relates to use of CD15s as a biomarker for eTreg cells. The present invention also relates to a method for identifying effector Treg cells (eTreg) in a fluid sample comprising the steps of i) detecting the cell surface expression of CD4, CD25, CD127 and CD15s markers on the cell population contained in the fluid sample and ii) concluding that the cells expressing …
Patent
Publication NumberUS 20200049127Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-02-14Publication Date2020-02-13
The invention relates to a method for designing a flexible blade or an articulated rigid blade with one or more torsion springs, for a wind turbine or a water turbine, the flexible blade being designed to passively control the pitch angle of the wind turbine or of the water turbine during operation, the method comprising the following steps: a) receiving the known geometric profile; b) determining a change in the optimal pitch angle, 0o opt rigid, as a function of the specific speed λ; c) det…
Patent
Publication NumberUS 10557040Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-12-14Publication Date2020-02-11
Coatings, for example polymer coatings or sol-gel coatings, including at least one layer of micrometric, individualised and mesostructured spherical particles. The particles having been created and loaded with at least one element selected from corrosion-inhibiting functional molecules and corrosion-inhibiting functional nano-objects, by a method having non-dissociable nebulization-heating steps that are continuous in a single reactor. The coatings form an anti-corrosion system, having mechan…
Patent
Publication NumberUS 10559247Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-03-18Publication Date2020-02-11
A method of controlling the display of images in the form of a pixel array, includes for a pixel of the array, asynchronous information representing events concerning the pixel is received, a first activation of the pixel is actuated at an activation time determined by a first event of the asynchronous information, and at least a second activation of the pixel is actuated in order to repeat the first activation of the pixel at respective times defined by a refresh sequence.
Patent
Publication NumberJP 6657225 B2Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-12-18Publication Date2020-02-07
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