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University (29K)Hospital (8.1K)Research Institution (4.4K)Other (3.3K)Company (451)Foundation (162)organization (7)Investor (5)
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Publication
ID31042319Published Date2019-08-15JournalCancer, 2019-08-15, Volume 125
Breast cancer therapies are associated with a risk of cardiac dysfunction, most commonly defined by changes in left ventricular ejection fraction (LVEF). Recently, the authors identified 3 classes of LVEF change after exposure to anthracyclines and/or trastuzumab using latent class growth modeling. The objective of the current study was to characterize the clinical, biochemical, and functional profiles associated with LVEF trajectory class membership.Transthoracic echocardiography and biomark…
Publication
ID30696608Published Date2019-08-15JournalInternational journal of cardiology, 2019-08-15, Volume 289
In breast cancer patients, coincidental detection of CAC at chest CT may be important in determining cardiovascular (CV) outcomes and facilitate CV disease primary prevention strategies.408 consecutive breast cancer patients referred to cardiac oncology clinic were included in the study. 256 patients without a prior history of coronary artery disease had undergone a chest CT. CT images were reviewed to detect CAC. Framingham risk score (FRS) was calculated and patient electronic medical recor…
Publication
ID31193845Published Date2019-09-01JournalPreventive medicine reports, 2019-09-01, Volume 15
Despite the evidence supporting the benefits of physical activity in the prevention and treatment of most medical conditions, physical activity remains under-prescribed by physicians. Medical students will form habits during training that they are likely to maintain as future physicians. The overall purpose of this study was to investigate the underlying mechanism(s) contributing to frequency in recommending physical activity, to provide insight into how we can increase physical activity reco…
Publication
ID31195122Published Date2019-09-01JournalComparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2019-09-01, Volume 235
Flight costs play an important role in determining the behavior, ecology, and physiology of birds and bats. Mechanical flight costs can be estimated from aerodynamics. However, measured metabolic flight costs (oxygen consumption rate) are less accurately predicted by flight theory, either because of (1) variation in flight efficiency across species, (2) variation in how basal costs interact with flight costs or (3) methodological biases. To tease apart these three hypotheses, we conducted a p…
Clinical Trial
Clinical Trial IDNCT03782818Start Date2019-09-01Completion Date0030-02-27PhasePhase 1Study TypeInterventionalStatusNot yet recruiting
The main OBJECTIVE of this proposal is to extend our preclinical findings on the role of DNA damage and poly(ADP-ribose) polymerases (PARP) inhibition as a therapy for a devastating disease, pulmonary arterial hypertension (PAH), to early-phase clinical trials. We, and others, have published strong evidence that DNA damage accounts for disease progression in PAH and showed that PARP1 inhibition can reverse PAH in several animal models1. Interestingly, PARP1 inhibition is also cardioprotective…
Publication
ID31273437Published Date2019-09-01JournalEuropean journal of nuclear medicine and molecular imaging, 2019-09-01, Volume 46
Single-photon emission computed tomography (SPECT) combined with computed tomography (CT) was introduced as a hybrid SPECT/CT imaging modality two decades ago. The main advantage of SPECT/CT is the increased specificity achieved through a more precise localization and characterization of functional findings. The improved diagnostic accuracy is also associated with greater diagnostic confidence and better inter-specialty communication.This review presents a critical assessment of the relevant …
Publication
ID30949436Published Date2019-09-01JournalInternet interventions, 2019-09-01, Volume 17
To assess the availability, readability, and privacy-related content of the privacy policies and terms of agreement of mental health apps available through popular digital stores.Popular smartphone app stores were searched using combinations of keywords "track" and "mood" and their synonyms. The first 100 apps from each search were evaluated for inclusion and exclusion criteria. Apps were assessed for availability of a privacy policy (PP) and terms of agreement (ToA) and if available, these d…
Publication
ID31199960Published Date2019-09-01JournalMicrovascular research, 2019-09-01, Volume 125
High aerobic fitness may prevent age-related decrements in cutaneous vasodilation while type 2 diabetes may exacerbate this decline. The mechanisms underlying these responses remain unclear, but may be due to an excess of reactive oxygen species. We hypothesized that superoxide scavenging or NADPH oxidase inhibition would improve cutaneous vasodilation in older adults exercising in the heat, particularly in healthy low-fit individuals and those with type 2 diabetes.Twenty seven older adults w…
Clinical Trial
Clinical Trial IDNCT03833609Start Date2019-09-01Completion Date2022-04-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The primary objectives of the proposed pilot randomized controlled trial (RCT) will be to examine: (1) the feasibility of a full RCT to evaluate the effectiveness of two popular types of physical activity (PA), a yoga training program and an aerobic dance training program, in female adolescents (13 to 18 years old) with juvenile idiopathic arthritis (JIA) compared to a wait list control group; and (2) the acceptability of these interventions. A three-arm prospective randomized open-label stud…
Publication
ID30711826Published Date2019-09-01JournalJournal of behavior therapy and experimental psychiatry, 2019-09-01, Volume 64
Self-referent information is critical for navigating the social realm, as we constantly use both verbal and non-verbal feedback in our interactions to understand ourselves and the world. In non-clinical samples, a memory bias for positive self-referent information has been observed, while a negativity bias has been observed among those with depression and anxiety. While research suggests that visual and auditory information is processed differently, no study has yet examined if memory biases …
We found 29,048 documents that match your Search
Research Grants: 49
Publications: 28,334
Patents: 315
Clinical Trials: 343
Opportunities: 7

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