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ID31987935Published Date2020-04-06JournalBehavioural brain research, 2020-04-06, Volume 383
The known effects of aging on the brain and behavior include impaired cognition, increases in anxiety and depressive-like behaviors, and reduced locomotor activity. Environmental exposures and interventions also influence brain functions during aging. We investigated the effects of normal aging under controlled environmental conditions and in the absence of external interventions on locomotor activity, cognition, anxiety and depressive-like behaviors, immune function and hippocampal gene expr…
Publication
ID32007787Published Date2020-04-15JournalJournal of neuroimmunology, 2020-04-15, Volume 341
Distinguishing neurosarcoidosis (NS) from multiple sclerosis (MS) remains challenging and available parameters lack discriminatory power. Comprehensive flow cytometry data of blood and CSF leukocytes of patients with NS (n = 24), MS (n = 49) and idiopathic intracranial hypertension (IIH, n = 52) were analyzed by machine learning algorithms. NS featured a specific immune cell pattern with increased activated CD4+ T cells in CSF and increased plasma cells in blood. Combining blood and CSF param…
Publication
ID31734281Published Date2020-04-01JournalDevelopmental and comparative immunology, 2020-04-01, Volume 105
In insects and crustaceans, thousands of Down syndrome cell adhesion molecules (Dscam) can be generated by alternative splicing of variable exons from a single-locus gene, Dscam-hv. This extraordinarily versatile gene (38,016 protein isoforms produced in Drosophila) was first proposed to be involved in exon guidance and subsequently implicated in immunity as a hypervariable immune molecule. Almost 20 y after discovery of Dscam-hv, there have been many studies in insects and crustaceans regard…
Publication
IDDOI:10.1177/0192513x19878864Published Date2020-04-01JournalJournal of Family Issues, 2020-04-01, Volume 41
The transition to parenthood (TTP) often is associated with declines in couple relationship satisfaction. The current study evaluated changes in three relationship behaviors, namely communication, dyadic coping and relationship self-regulation, across the TTP and the association of those behaviors with relationship satisfaction. One hundred and three couples completed questionnaires twice before and three times after the birth of their first child. Prenatally, all behaviors were stable, excep…
Publication
ID31517588Published Date2020-04-01JournalPersonality & social psychology bulletin, 2020-04-01, Volume 46
Grandiose narcissism has been linked to initial popularity but to later unpopularity in peer groups and laboratory contexts. Do these effects on peer relationships also emerge in larger real-life contexts and what are the underlying behavioral processes (i.e., behavioral expressions, interpersonal perceptions)? Using data from the longitudinal CONNECT field study ( = 126), we investigated effects of agentic and antagonistic aspects of grandiose narcissism on emerging popularity in a complete …
Publication
ID31864795Published Date2020-04-01JournalSeminars in cell & developmental biology, 2020-04-01, Volume 100
In many organisms, primordial germ cells (PGCs) are specified at a different location than where the gonad forms, meaning that PGCs must migrate toward the gonad within the early developing embryo. Following species-specific paths, PGCs can be passively carried by surrounding tissues and also perform active migration. When PGCs actively migrate through and along a variety of embryonic structures in different organisms, they adopt an ancestral robust migration mode termed "amoeboid motility", …
Publication
ID31907866Published Date2020-04-01JournalJournal of molecular neuroscience : MN, 2020-04-01, Volume 70
The purpose of the study was studying the influence of different NOD agonists on the morphological phenotype of primary murine microglia and to examine their influence on characteristic cytokines. Primary CD11b-positive cells were isolated from the brain of neonatal mice. The microglial phenotype of the cells was examined by ionized calcium-binding adapter molecule (Iba)1 staining. After14 days in culture, these cells were stimulated by iE-DAP, L18-MDP, or M-TriDAP as NOD1, NOD2, and NOD1/2 a…
Publication
ID31446499Published Date2020-04-01JournalOdontology, 2020-04-01, Volume 108
The aim was to compare the shaping ability of different rotary nickel-titanium instruments in simulated S-shaped canals. One hundred S-shaped canals in resin blocks were prepared to an apical size 25 using F6 SkyTaper (Komet), Silk Files .04, Silk Files .06, Prototypes .04, and Prototypes .06 (all Mani) (20 canals/group). Material removal was measured at 20 measuring points, beginning 1 mm from the endpoint of preparation. Incidence of canal aberrations, preparation time, and instrument failu…
Publication
ID32004802Published Date2020-04-01JournalCortex; a journal devoted to the study of the nervous system and behavior, 2020-04-01, Volume 125
Several studies suggest that highly schizotypal individuals display a deficit in smooth pursuit eye movements (SPEM), which are considered an important biomarker of schizophrenia. In schizophrenia, abnormal SPEM is thought to be driven by impairments in motion perception. In schizotypy, the processes underlying reduced SPEM performance have not been examined so far, and there are no studies on motion perception deficits in schizotypy. Thus, in this registered report, we aimed to investigate w…
Publication
ID31887598Published Date2020-04-01JournalEnvironmental pollution (Barking, Essex : 1987), 2020-04-01, Volume 259
Glyphosate is one of the most used herbicides in the world. The fate of glyphosate in tropical soils may be different from that in soils from temperate regions. In particular, the amounts and types of non-extractable residues (NER) may differ considerably, resulting in different relative contributions of xenoNER (sorbed and sequestered parent compound) and bioNER (biomass residues of degraders). In addition, environmental conditions and agricultural practices leading to total organic carbon (…
We found 11,408 documents that match your Search
Research Grants: 96
Publications: 10,384
Patents: 346
Clinical Trials: 550
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