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ID31706624Published Date2020-04-01JournalInternational journal of cardiology, 2020-04-01, Volume 304
Limited data exist on the association between circulating suppression of tumorigenicity 2 (ST2) and recurrent hospitalizations and emergency department (ED) encounters in outpatients with heart failure (HF). In addition, data on ST2 in African American patients with HF are scarce.We evaluated 307 outpatients with HF (age, 57 ± 12 years; 64.2% men; 51.5% Caucasian, 45.6% African American; median ejection fraction, 35%; ischemic etiology, 41.4%). Median ST2 was 37.8 ng/mL (29.6-51.4).After a me…
Publication
ID32059882Published Date2020-04-01JournalCarbohydrate polymers, 2020-04-01, Volume 233
In this study, the impact of drug and hydroxypropyl methylcellulose acetate succinate (HPMCAS) grades physicochemical properties on extrusion process, dissolution and stability of the hot melt extruded amorphous solid dispersions (ASDs) of nifedipine and efavirenz was investigated. Incorporation of drugs affected the extrusion temperature required for solid dispersion preparation. Differential scanning calorimetry and powder X-ray diffraction studies confirmed the amorphous conversion of the …
Publication
ID31981957Published Date2020-04-01JournalPhytochemistry, 2020-04-01, Volume 172
Eleven diarylpentanoid/norlignan glucosides, along with five other specialized metabolites, were isolated and characterized from the hydro-alcoholic extract of Hypoxis hemerocallidea corms. Hypoxhemerolosides A-F were found to be undescribed compounds. Curcapicycloside was isolated and identified for the first time in its original form, previously it was reported as a methylated derivative. In addition, (1S,2R)-1-(3,4-dihydroxyphenyl)-5-(4-β-D-glucopyranoxy-3-hydroxyphenyl)-1-methoxypent-4-yn…
Publication
ID32097193Published Date2020-04-01JournalJournal of acquired immune deficiency syndromes (1999), 2020-04-01, Volume 83
Depression plays a key role in suboptimal HIV outcomes, possibly mediated by adherence self-efficacy beliefs and antiretroviral treatment (ART) adherence behavior. Applying social-cognitive theory, we examined a longitudinal sequential path model of the association between depressive symptoms and viral nonsuppression in women with HIV (WWH) through these mediating mechanisms.This was an observational longitudinal study using data from the Women's Adherence and Visit Engagement substudy of the…
Publication
ID31942692Published Date2020-04-01JournalJournal of racial and ethnic health disparities, 2020-04-01, Volume 7
There is growing recognition that a singular focus on biomedical treatments is insufficient to address the HIV prevention and health-care needs of Black men who have sex with men (Black MSM). Ending the HIV epidemic requires a multifactorial approach accounting for the social, cultural, economic, and environmental factors that drive transmission of HIV and other STDs. The two case studies presented were implemented by community-based organizations that have extensive experience with the targe…
Publication
ID32043947Published Date2020-04-01JournalRadiology, 2020-04-01, Volume 295
Background Although several deep learning (DL) calcium scoring methods have achieved excellent performance for specific CT protocols, their performance in a range of CT examination types is unknown. Purpose To evaluate the performance of a DL method for automatic calcium scoring across a wide range of CT examination types and to investigate whether the method can adapt to different types of CT examinations when representative images are added to the existing training data set. Materials and M…
Publication
ID31782046Published Date2020-04-01JournalJournal of community genetics, 2020-04-01, Volume 11
Use of biobanks for future genetic/genomic testing has increased. Biospecimens are increasingly being collected from infants/children; however, little is known about attitudes towards collection of biospecimens from postpartum women and their child. Using a hypothetical consent, this study investigated willingness to participate and attitudes, beliefs, and concerns related to consent materials requesting the biobanking genetic samples. A cross-sectional mixed methods design included women who…
Publication
ID32150640Published Date2020-04-01JournalWest African journal of medicine, 2020-04-01, Volume 37
Cases of West Nile Virus (WNV), co-existent with Human Immuno deficiency Virus (HIV), are rare with less than eleven cases in the literature. This clinical combination has an overall mortality of about 30%, as WNV has greater risk in patients with an immunocompromised status. Distinguishing between an acute retroviral HIV episode and a WNV infection can be a clinical dilemma. They present with similar symptoms including headaches, joint pains and fever, and a high index of suspicion and clini…
Publication
ID30570444Published Date2020-04-01JournalJournal of American college health : J of ACH, 2020-04-01, Volume 68
Stair climbing is considered a good physical activity. Motivational signage has been successful in promoting stair usage in various settings. This study was to investigate the effects of motivational signage on stair usage in a Hispanic serving institution. A total of 31,067 pedestrians were observed from February to March 2013. Stair usage was monitored for 9 h per day each week at phase 1 (baseline), 2 (intervention), and 3 (post-intervention). Overall, participants' stair usage was higher …
Publication
IDDOI:10.1161/hypertensionaha.119.13887Published Date2020-04-01JournalHypertension, 2020-04-01, Volume 75
The National Heart, Lung, and Blood Institute convened a multidisciplinary working group of hypertension researchers on December 6 to 7, 2018, in Bethesda, MD, to share current scientific knowledge in hypertension and to identify barriers to translation of basic into clinical science/trials and implementation of clinical science into clinical care of patients with hypertension. The goals of the working group were (1) to provide an overview of recent discoveries that may be ready for testing i…
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