13
13
14
14
16
16
23
23
24
24
21
21
31
31
33
33
29
29
42
42
2019
2009
University (433)Research Institution (35)Hospital (7)
1 - 10 of 433
Sort by
Publication
ID31683717Published Date2019-10-31JournalMicromachines, 2019-10-31, Volume 10
Electroosmotic flow (EOF) of viscoelastic fluid with Linear Phan-Thien-Tanner (LPTT) constitutive model in a nanochannel connecting two reservoirs is numerically studied. For the first time, the influence of viscoelasticity on the EOF and the ionic conductance in the micro-nanofluidic interconnect system, with consideration of the electrical double layers (EDLs), is investigated. Regardless of the bulk salt concentration, significant enhancement of the flow rate is observed for viscoelastic f…
Publication
ID31653008Published Date2019-10-24JournalCancers, 2019-10-24, Volume 11
These studies compared the efficacies of our clinical agent galeterone (Gal) and the FDA-approved prostate cancer drug, enzalutamide (ENZ) with two lead next generation galeterone analogs (NGGAs), VNPP414 and VNPP433-3β, using prostate cancer (PC) in vitro and in vivo models. Antitumor activities of orally administered agents were also assessed in CWR22Rv1 tumor-bearing mice. We demonstrated that Gal and NGGAs degraded AR/AR-V7 and Mnk1/2; blocked cell cycle progression and proliferation of h…
Publication
ID31266816Published Date2019-10-01JournalMolecular cancer research : MCR, 2019-10-01, Volume 17
Alternative splicing (AS) has been shown to participate in prostate cancer development and progression; however, a link between AS and prostate cancer health disparities has been largely unexplored. Here we report on the cloning of a novel splice variant of that is preferentially expressed in African American (AA) prostate cancer. This novel variant () omits exon 14, comprising 123 nucleotides that encode the activation loop in the intracellular split kinase domain. Ectopic overexpression of …
Publication
ID30888683Published Date2019-10-01JournalJournal of neurochemistry, 2019-10-01, Volume 151
Herpes simplex virus-type 1 (HSV-1) infection of sensory neurons may lead to a significant reduction in the expression of voltage-activated Na and Ca channels, which can disrupt the transmission of pain information. Viral infection also results in the secretion of various pro-inflammatory cytokines, including interleukin (IL)-6. In this work, we tested whether IL-6 regulates the expression of Na and Ca channels post-HSV-1 infection in ND7/23 sensory-like neurons. Our results demonstrate that …
Publication
ID31330083Published Date2019-10-01JournalJournal of applied microbiology, 2019-10-01, Volume 127
To develop a process risk model (PRM) for evaluating the safety of individual lots of ground chicken (GC) contaminated with Salmonella (Salm).Data for prevalence, number and serotype of Salm were collected with 25 g samples of GC using a combination of methods (whole sample enrichment, quantitative polymerase chain reaction, cultural isolation and serotyping). These data were used to develop a predictive model for Salm contamination of GC as a function of serving size from 25 to 300 g. This m…
Publication
ID31389663Published Date2019-10-01JournalMolecular nutrition & food research, 2019-10-01, Volume 63
Obesity is a complex disease and a major public health epidemic. Chronic, low-grade inflammation is a common underlying feature of obesity and associated metabolic diseases; adipose tissue is a major contributor to this systemic inflammation. Evidence shows that obesity-associated inflammation may originate from gut dysfunction, including changes in intestinal bacteria or microbiome profiles. Increasingly, food and plant bioactive compounds with antioxidant and anti-inflammatory properties ar…
Publication
ID30744332Published Date2019-09-01JournalAsian-Australasian journal of animal sciences, 2019-09-01, Volume 32
The objective of the present study was to investigate pork quality from Hereford×Berkshire (HB) female and intact male pigs reared outdoors in an alternative production system.Berkshire purebred sows were artificially inseminated, once in the fall and again in the spring of the following year, with semen from Hereford boars and managed free of antibiotics in an outdoor hoop structure until the last month of pregnancy, after which they were moved to a pasture-based unit of 0.8 hectares with in…
Publication
ID31619837Published Date2019-09-01JournalAmerican journal of pharmaceutical education, 2019-09-01, Volume 83
Abstract not available
Research Grant
Project Number1SC1GM127256-01Funding AgencyNational Institutes of HealthEffective Date2019-09-01Expiration Date2020-08-31Funding Amount$387,500
PROJECT SUMMARY/ABSTRACT Prostate cancer (PCa) is now the most frequently diagnosed cancer and the second most common cause of cancer deaths in men in United States. Notably, African Americans (AAs) exhibited 1.6-fold higher incidence and 2.4-fold higher mortality rates compared to European Americans (EAs). Despite multiple socioeconomic factors postulated to explain the observed PCa disparities, higher recurrence and mortality rates remained even after adjustment of socioeconomic status in A…
Publication
IDIEEE:8700624Published Date2019-09-01JournalIEEE Transactions on Microwave Theory and Techniques, 2019-09-01, Volume 67
This paper describes a software-defined radar sensor based on successive multiple-frequency continuous-wave (S-MFCW) modulation. S-MFCW is a radar modulation technique capable of detecting static and moving targets with high accuracy while modulating the transmitted signal over a narrow frequency bandwidth. The proposed software-defined radar is implemented as a highly reconfigurable system made of a field-programmable gate array (FPGA)-based system-on-chip (SoC), a wideband homodyne radio fr…
We found 433 documents that match your Search
Research Grants: 118
Publications: 304
Patents: 11

Wellspring Search is the world's most comprehensive collection of enriched content about emerging and licensable technology innovations.


Already a member? Sign in