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Publication
ID32298743Published Date2020-05-30JournalInternational journal of pharmaceutics, 2020-05-30, Volume 582
The hindrances in achieving clinically translatable anticancer platforms are being tackled through nanotechnology-based formulations. In this study, stimuli-responsive, phytoactive constituent-loaded nanophytoliposomes were fabricated for designing a specific antitumor platform. Ursolic acid (UA)-loaded nanophytoliposomes (UA-PLL-HA.P) enwrapped in a poly-L-lysine (PLL) coat and hyaluronic acid (HA) were nanosized; these nanophytoliposomes had spherical morphology, slightly negative charge, a…
Publication
ID32444011Published Date2020-06-01JournalInfectious disease clinics of North America, 2020-06-01, Volume 34
The recognition of the role of complement and Janus kinase (JAK)-dependent cytokines in the pathogenesis of inflammatory and immune-mediated disorders has revolutionized the treatment of a myriad of rheumatological and inflammatory diseases. C5 inhibitors and Janus kinase inhibitors have emerged as attractive therapeutic options. Because of the blockage of immune pathways, these targeted therapies carry an increased risk of infection. This article reviews the mechanism of action and the appro…
Publication
ID32446483Published Date2020-06-01JournalThe Journal of pediatrics, 2020-06-01, Volume 221
To determine the interobserver agreement of history and physical examination findings in children undergoing evaluation in the emergency department (ED) for headaches.We conducted a prospective, cross-sectional study of children aged 2-17 years evaluated at 3 tertiary-care pediatric EDs for non-traumatic headaches. Two clinicians independently completed a standardized assessment of each child and documented the presence or absence of history and physical examination variables. Unweighted κ st…
Publication
IDIEEE:8680621Published Date2020-06-01JournalIEEE Journal of Emerging and Selected Topics in Power Electronics, 2020-06-01, Volume 8
This paper is focused on a photovoltaic system architecture based on series-connected low-voltage ac (LVac) microinverters. In contrast to standard microinverters, LVac microinverters do not require high step-up conversion stages, which leads to potentials for improved efficiency and reduced cost. This paper proposes a distributed autonomous control strategy for the LVac microinverters, where each module is operated autonomously by a controller that regulates instantaneous output power. Model…
Publication
ID32213352Published Date2020-06-01JournalJournal of psychiatric research, 2020-06-01, Volume 125
Vitamin D deficiency is associated with immune dysregulation, increased vulnerability to infections, depression, and suicidal behavior. One mediator of vitamin D-dependent immune regulation and antimicrobial defense is the cathelicidin antimicrobial peptide (LL-37), encoded by the cathelicidin-related antimicrobial peptide (CRAMP) gene. We compared the mRNA expression of the CRAMP gene, the vitamin D receptor (VDR) gene, as well as the CYP27B1 and CYP24A1 genes (involved in vitamin D metaboli…
Publication
ID32362229Published Date2020-06-01JournalHypertension (Dallas, Tex. : 1979), 2020-06-01, Volume 75
It remains uncertain whether intensive control of blood pressure (BP) results in a lower risk of atrial fibrillation (AF) in patients with hypertension. Using data from SPRINT (Systolic Blood Pressure Intervention Trial), which enrolled participants with hypertension at increased risk of cardiovascular disease, we examined whether intensive BP lowering (target systolic BP [SBP]
Publication
IDDOI:10.1177/0011128720911640Published Date2020-06-01JournalCrime & Delinquency, 2020-06-01, Volume 66
Juvenile justice systems today have various methods to sanction serious, violent, and chronic delinquents. One of these methods is through blended sentencing. Broadly, blended sentencing processes allow for juvenile justice sanctioning first and then, if needed, criminal justice sanctioning—including placement in adult prisons. The current study examines the recidivism outcomes of blended-sentenced youth transferred to adult prisons following a period of state juvenile incarceration compared …
Research Grant
Award Number1927153Funding AgencyNational Science FoundationEffective Date2020-06-01Expiration Date2023-05-31Funding Amount$274,984
The Laurentide Ice Sheet (LIS) once covered much of the North American continent. It grows and expands during cold periods and contracts during warm periods in Earth's recent geological past. Today, the last remaining vestige of the LIS is the Barnes Ice Cap, located on central Baffin Island. While tracking the size of the LIS at times when it was significantly larger than today is relatively straightforward, constraining the size and frequency of LIS minima is much more challenging but can p…
Publication
ID32412383Published Date2020-06-01JournalAdvances in physiology education, 2020-06-01, Volume 44
Few discussions regarding instructional methods incite as much passion as the debate over dissection versus prosection. Despite numerous analyses, few studies have isolated the impact of dissection versus prosection from the numerous variables that are involved in anatomy education. This study used a retrospective design to assess the effect of peer teaching with dissection or prosection on anatomical knowledge retention of the peer teachers. Exam scores were analyzed from three cohorts of st…
Publication
ID32209646Published Date2020-06-01JournalDiabetes care, 2020-06-01, Volume 43
To identify sleep duration trajectories from early to middle adulthood and their associations with incident type 2 diabetes.Using a group-based modeling approach, we identified sleep duration trajectories based on sleep duration in ages 20-25, 26-35, 36-45, and 46+ years, which were retrospectively assessed in 2009 among 60,068 women from the Nurses' Health Study II (median age 54.9 years) who were free of diabetes, cardiovascular disease, and cancer. We investigated the prospective associati…
We found 150,147 documents that match your Search
Research Grants: 39,662
Publications: 104,627
Patents: 3,970
Clinical Trials: 1,460
Opportunities: 46
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