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Publication
ID32563607Published Date2020-07-14JournalVaccine, 2020-07-14, Volume 38
The Global Vaccine Action Plan 2011-2020 (GVAP) was developed to realize the ambitions of the Decade of Vaccines - that all individuals and communities enjoy lives free from vaccine-preventable diseases. It included a comprehensive monitoring and evaluation/accountability framework to assess progress towards global targets with recommendations for corrective actions. While many of the GVAP targets are very unlikely to be met by the end of 2020, substantial progress has nevertheless been made,…
Publication
ID32549035Published Date2020-07-09JournalHuman biology, 2020-07-09, Volume 91
To date, some genetic studies offer medical benefits but lack a clear pathway to benefit for people from underrepresented backgrounds. Historically, Indigenous people, including the Diné (Navajo people), have raised concerns about the lack of benefits, misuse of DNA samples, lack of consultation, and ignoring of cultural and traditional ways of knowing. Shortly after the Navajo Nation Human Research Review Board was established in 1996, the Navajo Nation recognized growing concerns about gene…
Publication
IDDOI:10.1175/jcli-d-19-0555.1Published Date2020-07-15JournalJournal of Climate, 2020-07-15, Volume 33
Abstract The Pacific–North American (PNA) teleconnection pattern has been linked both to tropical phenomena, including the Madden–Julian oscillation (MJO) and El Niño–Southern Oscillation (ENSO), and to internal extratropical processes, including interactions with the zonally varying basic state and synoptic eddies. Many questions remain, however, concerning how these various relationships act, both separately and together, to yield observed PNA variability. Using linear inverse modeling (LIM…
Research Grant
Award Number2005170Funding AgencyNational Science FoundationEffective Date2020-07-15Expiration Date2023-06-30Funding Amount$254,816
Nontechnical Abstract:Ferroelectric nematics are fluids of essentially rod-shaped molecules that spontaneously organize into domains with macroscopic polar order. The recent discovery of this liquid crystal phase has created an opportunity to probe and understand the appearance of spontaneous polarization in a broad range of soft materials, including polymers, biomaterials, liquid crystals and colloids. The polar nature of the ferroelectric nematic makes it attractive for a host of novel…
Publication
ID32299040Published Date2020-07-15JournalJournal of hazardous materials, 2020-07-15, Volume 394
The exploration of emergency materials with ultra-fast adsorption rate and great adsorption capability of released U(VI) ions is essentially urgent. The present work successfully fabricated bundle-like hydroxyapatite (B-HAP) microstructures which composed of numerous nanorods by employing a facile and green method. The B-HAP was applied to treat the U(VI) containing wastewater. The abatement of U(VI) by B-HAP was very rapid and the saturated adsorption capacity was superior; over 96.7 % of U(…
Publication
ID32589990Published Date2020-07-15JournalInternational journal of radiation oncology, biology, physics, 2020-07-15, Volume 107
The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international group of experts in lung cancer radiotherapy established this practice recommendation pertaining to whether and how to adapt radiotherapy for lung cancer in the COVID-19 pandemic.For this ESTRO & ASTRO endorsed project, 32 experts in lung cancer radiotherapy contributed to a modified Delphi consensus process. We assessed potential adaptati…
Publication
ID32416558Published Date2020-07-15JournalJournal of neuroimmunology, 2020-07-15, Volume 344
Immune checkpoint inhibitors (ICIs) represent a major development in cancer treatment, allowing for improved survival and disease control in an expanding number of cancer types. Due to their mechanism of disrupting immunologic homeostasis, ICIs are frequently associated with adverse effects, termed immune related adverse effects (irAE). These side effects can affect any organ system, including the central and peripheral nervous systems. We present a case of a 47 year old man with stage IIIc m…
Publication
ID32502935Published Date2020-07-15JournalMolecular and cellular endocrinology, 2020-07-15, Volume 512
Decidual mechanistic target of rapamycin (mTOR) is inhibited, amino acid response (AAR) and protein kinase CK2 are activated, and IGF (insulin-like growth factor) binding protein (IGFBP)-1 is hyperphosphorylated in human intrauterine growth restriction (IUGR). Using decidualized human immortalized endometrial stromal cells (HIESC), we hypothesized that hypoxia and leucine deprivation causing inhibition of decidual IGF-1 signaling is mediated by mTOR, AAR, CK2 and IGFBP-1 phosphorylation. Mass…
Publication
IDDOI:10.1175/jcli-d-19-0802.1Published Date2020-07-15JournalJournal of Climate, 2020-07-15, Volume 33
Abstract Whether distinct wintertime U.S. climate conditions exist for central-Pacific (CP) versus eastern-Pacific (EP) El Niño events is explored using atmospheric and coupled ocean–atmospheric models. Results using the former agree with most prior studies indicating different U.S. temperature and precipitation patterns associated with El Niño flavors. Causes are traced to equatorial rainfall sensitivity to both magnitudes and spatial patterns of sea surface temperatures (SSTs) distinguishin…
Publication
ID32239636Published Date2020-07-06JournalAngewandte Chemie (International ed. in English), 2020-07-06, Volume 59
As agonists of TLR7/8, single-stranded RNAs (ssRNAs) are safe and promising adjuvants that do not cause off-target effects or innate immune overactivation. However, low stability prevents them from mounting sufficient immune responses. This study evaluates the adjuvant effects of ssRNA derived from the cricket paralysis virus intergenic region internal ribosome entry site, formulated as nanoparticles with a coordinative amphiphile, containing a zinc/dipicolylamine complex moiety as a coordina…
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Publications: 106,848
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