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University (118K)Hospital (9.2K)Research Institution (8.8K)Company (7.8K)Foundation (968)Investor (568)Other (113)
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Publication
ID32057333Published Date2020-02-24JournalVaccine, 2020-02-24, Volume 38
Measles is endemic in the Democratic Republic of the Congo (DRC), and 89-94% herd immunity is required to halt its transmission. Much of the World Health Organization African Region, including the DRC, has vaccination coverage below the 95% level required to eliminate measles, heightening concern of inadequate measles immunity.We assessed 6706 children aged 6-59 months whose mothers were selected for interview in the 2013-2014 DRC Demographic and Health Survey. History of measles was obtained…
Clinical Trial
Clinical Trial IDNCT03760458Start Date2020-03-01Completion Date0031-07-30PhasePhase 1/Phase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to examine the pharmacokinetics, safety, and tolerability of abacavir/dolutegravir/lamivudine dispersible and immediate release tablets in HIV-1-infected children less than 12 years of age.
Publication
ID31836357Published Date2020-03-01JournalJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020-03-01, Volume 29
Limb shaking is a rare manifestation of transient ischemic attacks (TIA) associated with carotid occlusion, mostly unilateral events. We describe the case of a 69 year-old man who presented with repeated episodes of irregular jerking movements in the bilateral upper and lower extremities, precipitated by standing up. Cerebral angiograms revealed occlusion of both internal carotid arteries, and the patient's symptoms responded to targeted blood pressure management. Physicians should be mindful…
Publication
ID31790144Published Date2020-03-01JournalThe Journal of clinical endocrinology and metabolism, 2020-03-01, Volume 105
Aging is associated with diminished testosterone (Te) secretion, which may be attributed to Leydig cell dysfunction, decreased pituitary stimulation, and altered Te feedback.To study all regulatory nodes-gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and Leydig cell-in the same cohort of healthy men.This was a placebo-controlled, blinded, prospectively randomized cross-over study in 40 men, age range 19 to 73 years, and body mass index (BMI) range 20 to 34.3 kg/m2. A submaxim…
Publication
ID31347227Published Date2020-03-01JournalNephrology (Carlton, Vic.), 2020-03-01, Volume 25
Patient-reported outcome measures of fatigue used in research in haemodialysis vary widely in the dimensions assessed; and the importance of these dimensions to patients and health professionals is unknown. This study aimed to identify the most important dimensions of fatigue to assess in patients on haemodialysis participating in trials.In an international survey, patients/caregivers and health professionals rated the absolute and relative importance of content and measurement dimensions to …
Publication
ID31676174Published Date2020-03-01JournalThe Journal of arthroplasty, 2020-03-01, Volume 35
Total knee arthroplasty requires careful surgical technique to attain the goal of a well-aligned and symmetrically balanced knee. Soft tissue balance and correct femoral component rotation are paramount in achieving these goals. The two competing techniques to select femoral component rotation and soft tissue balance are the gap balance technique and the measured resection technique.We performed a randomized, prospective study to compare the two techniques in patients undergoing simultaneous …
Publication
ID32058369Published Date2020-03-01JournalCritical care medicine, 2020-03-01, Volume 48
A companion article reports the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock. In this article, the investigators examine critical illness factors associated with these adverse outcomes.Prospective, cohort-outcome study, conducted 2013-2017.Twelve United States academic PICUs.Critically ill children, 1 month to 18 years, with community-acquired septic shock requiring vasoactive-inotropic support.Illness sev…
Publication
ID31502423Published Date2020-03-01JournalWiley interdisciplinary reviews. Cognitive science, 2020-03-01, Volume 11
Many of language's components, including communicating symbolic meaning, have neurobiological roots that go back millions of years in evolutionary time. The intersection with the human social survival strategy spawned additional adaptive meaning systems. Under conditions threatening survival in socially oriented human groups, extra-language meaning systems co-opted and adapted to facilitate unity, including the early formats of the arts. They would have percolated into cultural practice for t…
Publication
ID31647335Published Date2020-03-01JournalLeukemia & lymphoma, 2020-03-01, Volume 61
Treatment-free remission (TFR) in patients with chronic myeloid leukemia in chronic phase (CML-CP) is considered a feasible option, especially with the ability of second-generation tyrosine kinase inhibitors to induce higher rates of sustained deep molecular response (DMR). DASFREE is an open-label, single-arm, multicenter phase II trial assessing TFR after dasatinib discontinuation in patients with CML-CP ( = 84). At 2 years, TFR was 46% in all patients. Multivariate analyses revealed statis…
Publication
ID31439889Published Date2020-03-01JournalProstate cancer and prostatic diseases, 2020-03-01, Volume 23
M2-like macrophages are associated with the pathogenesis of castrate-resistant prostate cancer (CRPC). We sought to determine if dietary omega-3 fatty acids (ω-3 FAs) delay the development and progression of CRPC and inhibit tumor-associated M2-like macrophages.MycCap cells were grown subcutaneously in immunocompetent FVB mice. Mice were castrated when tumors reached 300 mm. To study effects of dietary ω-3 FAs on development of CRPC, ω-3 or ω-6 diets were started 2 days after castration and m…
We found 118,017 documents that match your Search
Research Grants: 49,324
Publications: 62,447
Patents: 722
Clinical Trials: 3,405
Web Documents: 2,119

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