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Publication
ID31031077Published Date2019-09-15JournalInternational journal of cardiology, 2019-09-15, Volume 291
Adults presenting with an unrepaired atrial septal defect and pulmonary arterial hypertension (ASD-PAH) are typically classified as "correctable" or "non-correctable". The use of directed PAH medical therapy in non-correctable ASD-PAH leading to favorable closure candidacy, repair status and long-term follow-up is not well studied. We therefore sought to characterize response to PAH targeted therapy in 'non-correctable' ASD-PAH.Nine North American tertiary care centers submitted retrospective…
Publication
ID31173725Published Date2019-09-15JournalBrain research, 2019-09-15, Volume 1719
Contextual threat learning is often associated with two processes: elemental and configural learning. Few studies have examined configural learning where subjects form a representation of the threat-related context as a gestalt whole from the individual features in the environment. The goal of the current study was to compare and contrast neural circuitry recruited by variation in demands placed on configural threat encoding. Subjects (N = 25) completed a configural threat learning task, wher…
Research Grant
Award Number1918564Funding AgencyNational Science FoundationEffective Date2019-09-15Expiration Date2020-08-31Funding Amount$22,554
What role do regional bodies have in the building and maintenance of civil society? This project, which trains a graduate student in methods of rigorous, empirical data collection and analysis, explores how notions of political belonging are formed and sustained between nation and region. In particular, it will explore new forms of political belonging and governance that exceed national borders, asking what can be learned from supra-national regional dynamics, processes, and imaginations that…
Research Grant
Award Number1936209Funding AgencyNational Science FoundationEffective Date2019-09-15Expiration Date2022-08-31Funding Amount$117,130
Cultivating diversity and broadening participation of historically underrepresented groups in the mathematical sciences are national goals that are essential components of the innovation engine that drives the nation?s economy. It is a complex problem to solve, and doing so requires a concerted effort. The Mathematical Sciences Institutes Diversity Initiative (MSIDI) is an ongoing collaboration among the NSF-funded mathematical sciences research institutes that aims to address this issue with…
Publication
ID31401953Published Date2019-09-30JournalPhilosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019-09-30, Volume 374
Pathogen spillover between different host species is the trigger for many infectious disease outbreaks and emergence events, and ecosystem boundary areas have been suggested as spatial hotspots of spillover. This hypothesis is largely based on suspected higher rates of zoonotic disease spillover and emergence in fragmented landscapes and other areas where humans live in close vicinity to wildlife. For example, Ebola virus outbreaks have been linked to contacts between humans and infected wild…
Research Grant
Award Number1926360Funding AgencyNational Science FoundationEffective Date2019-10-01Expiration Date2022-09-30Funding Amount$449,964
The separation of emulsified oil from waste water streams remains a significant industrial challenge. Membrane filtration is one of the few methods that can remove emulsified oil drops. However, the filtration of these drops is complicated by severe membrane fouling, where fluid passage through the membrane is slowed by particles or solutions at the surface. Developing an energy-efficient separation process for removing emulsified oil from water with minimal membrane fouling would benefit man…
Publication
ID31421598Published Date2019-10-01JournalJournal of psychiatric research, 2019-10-01, Volume 117
Although metabolic syndrome and cognitive inefficiencies are well-described common complications of schizophrenia, their association remains inconsistent, potentially due to poorly understood mechanisms underlying their relationship. Variability in the endothelial nitric oxide synthase (eNOS) gene, specifically the T-786C variant, has been separately associated with cognition and metabolic syndrome, with worse outcomes for eNOS-786C carriers likely occurring via negative effects on blood vess…
Research Grant
Award Number1936735Funding AgencyNational Science FoundationEffective Date2019-10-01Expiration Date2021-09-30Funding Amount$299,997
The University of California--Los Angeles will develop a literature matrix resource that will allow practitioners, researchers, non-profits, industry, and others interested in broadening participation in computing (BPC) to identify and assess relevant literature to inform their work. Currently, the Principal Investigator Dr. Linda Sax leads a national, mixed-method research project (the BRAID Research project) focused on efforts to recruit and retain women and students of color in undergradua…
Clinical Trial
Clinical Trial IDNCT03760458Start Date2019-10-01Completion Date0031-07-30PhasePhase 1/Phase 2Study TypeInterventionalStatusNot yet recruiting
The purpose of this study is to examine the pharmacokinetics, safety, and tolerability of abacavir/dolutegravir/lamivudine dispersible and immediate release tablets in HIV-1-infected children less than 12 years of age.
Publication
ID30894013Published Date2019-10-01JournalAIDS care, 2019-10-01, Volume 31
PrEP's potential benefit for men who have sex with men (MSM) who use stimulants may be limited by adherence or prescriber willingness to recommend PrEP due to concerns of non-compliance. Using data from PATH-PrEP, a 48-week study evaluating PrEP for MSM in Los Angeles, we modeled an interaction between stimulant use and condomless sex with multiple partners (CAS-MP) on prevention-effective dried blood spot tenofovir-diphosphate concentrations. At week 4, participants reporting stimulant use a…
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Publications: 49,315
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