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Publication
ID31177508Published Date2019-09-01JournalThe journal of physiological sciences : JPS, 2019-09-01, Volume 69
Our previous demonstration that severe experimental autoimmune encephalomyelitis (EAE) increases MnSOD protein abundance in the mouse kidney cortex led this study to elucidate the underlying mechanism with monensin-treated HEK293 cells as a model. Severe EAE increases mitochondrial protein abundance of SGK1 kinase and Tom20, a critical subunit of mitochondrial translocase in the renal cortex. In HEK293 cells, catalase inhibits monensin-induced increases of mitochondrial SGK1 and Tom20 protein…
Publication
ID31361722Published Date2019-09-01JournalSports medicine and arthroscopy review, 2019-09-01, Volume 27
Blood flow restriction (BFR) has been shown to produce beneficial adaptations to skeletal muscle. These adaptations have been documented in the civilian and military populations. BFR therapy may provide patients a safe method to begin strength training at earlier stages of rehabilitation to allow for earlier and more effective return to activity and improved military readiness. The purpose was to review BFR therapy physiology, complications, side effects, standardized treatment algorithms, an…
Publication
ID31134851Published Date2019-09-01JournalStress (Amsterdam, Netherlands), 2019-09-01, Volume 22
The literature has consistently emphasized a relationship between chronic stress and depression as well as the involvement of brain-derived neurotrophic factor (BDNF). It is also well known that there are gender disparities with regard to depression. However, there has been a lack of biobehavioral experimental investigations of these relationships with regard to the role of BDNF in sex differences in response to stress. It was hypothesized that stress (chronic unpredictable mild stress [CUMS]…
Publication
ID31230888Published Date2019-09-01JournalThe Journal of pediatrics, 2019-09-01, Volume 212
To determine the risk of bacterial meningitis in infants aged 29-90 days with evidence of urinary tract infection (UTI).PubMed (MEDLINE), Embase, and the Cochrane Library were systematically searched for studies reporting rates of meningitis in infants aged 29-90 days with abnormal urinalysis or urine culture. Observational studies in infants with evidence of UTI who underwent lumbar puncture (LP) reporting age-specific event rates of bacterial meningitis and sterile cerebrospinal fluid pleoc…
Publication
ID30028355Published Date2019-09-01JournalInternational journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 2019-09-01, Volume 38
TP53 gene mutations are known to manifest in distinct p53 immunohistochemical staining patterns; overexpression, wild-type, and null. These stratified staining patterns are routinely utilized in subtyping ovarian cancer subtypes. Three ovarian cancer cell lines were used in the construction of an immunohistochemical p53 expression pattern control panel that highlight respective TP53 mutation status. The cell line control panel sections demonstrated consistent clean and easily interpretable p5…
Publication
ID31299506Published Date2019-09-01JournalGait & posture, 2019-09-01, Volume 73
To assist with forward progression during gait, persons with unilateral lower-limb amputation typically perform more work within the unaffected versus affected limb. However, prior cross-sectional (>2years post-amputation) studies cannot necessarily elucidate the origin or evolution of these compensatory mechanics.Do lower limb joint kinetics change during the initial stages of independent ambulation among persons with lower-limb amputation?Nine males with unilateral lower-limb amputation (6 …
Publication
ID30542053Published Date2019-09-01JournalProstate cancer and prostatic diseases, 2019-09-01, Volume 22
Germline mutations in BRCA2 have been linked to a higher risk of prostate cancer (PCa), and high frequency of BRCA1 and BRCA2 (BRCA1/2) gene alterations was recently reported in metastatic castration-resistant PCa specimens. Mutations in BRCA2 vary in racial and ethnic groups including African-American (AA) and Caucasian-American (CA) populations.BRCA1 and BRCA2 genes were sequenced (Ion AmpliSeq targeted sequencing) in archived blood DNA specimens in 1240 PCa patients, including 30% AA patie…
Publication
ID30444736Published Date2019-09-01JournalCancer nursing, 2019-09-01, Volume 42
Childhood cancer profoundly impacts the well-being of many parental caregivers in the United States yearly. Empirical evidence is extensive for negative well-being and scarce for positive well-being in this population.Study aims were to (1) describe resilience, self-transcendence, and positive (general well-being) and negative well-being (depression and anxiety); (2) examine if caregiver-related personal factors (resilience and/or demographic characteristics) and/or child-related contextual f…
Publication
ID31282712Published Date2019-09-01JournalPsychotherapy (Chicago, Ill.), 2019-09-01, Volume 56
Clinical practice guidelines (CPGs) are used to support clinicians and patients in diagnostic and treatment decision-making. Along with patients' preferences and values, and clinicians' experience and judgment, practice guidelines are a critical component to ensure patients are getting the best care based on the most updated research findings. Most CPGs are based on systematic reviews of the treatment literature. Although most reviews are now restricted to randomized controlled trials, others…
Publication
ID31032460Published Date2019-09-01JournalContemporary clinical trials communications, 2019-09-01, Volume 15
Achieving adequate retention rates in clinical trials is essential to ensuring meaningful results. Although financial reimbursement is an effective strategy to increase participant retention, current policies restrict the use of federal funds to reimburse U.S. active duty Service members for research participation. It is unknown whether permitting financial reimbursement among this population would improve trial retention rates. A recent randomized effectiveness trial received approval to pro…
We found 8,253 documents that match your Search
Research Grants: 19
Publications: 7,974
Patents: 161
Clinical Trials: 99

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