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ID31996315Published Date2020-03-23JournalNeuroscience letters, 2020-03-23, Volume 722
Primary somatosensory cortex (S1) is involved in pain processing and thus its suppression using neuromodulatory techniques such as continuous theta burst stimulation (cTBS) might be a potential pain management strategy in patients with neuropathic pain. cTBS over S1 is known to elevate pain threshold in young adults. However, the time course of this after-effect is unknown. Furthermore, the effect of cTBS over S1 on pain threshold might be confounded by changes in the excitability of primary …
Publication
ID32184959Published Date2020-03-12JournalACS medicinal chemistry letters, 2020-03-12, Volume 11
We describe here the design, synthesis, and biological evaluation of a reactive oxygen species (ROS)-activatable prodrug for the selective delivery of , a small molecule ATF6 activator, for ischemia/reperfusion injury. ROS-activatable prodrug and a negative control unable to release free drug were synthesized and examined for peroxide-mediated activation. Prodrug blocks activity of by its inability to undergo metabolic oxidation by ER-resident cytochrome P450 enzymes such as Cyp1A2, probed di…
Publication
ID32083865Published Date2020-03-10JournalJournal of the American Chemical Society, 2020-03-10
Understanding the dynamic changes at the active site during catalysis is a fundamental challenge that promises to improve catalytic properties. While performing Arrhenius studies during H oxidation over Au/TiO catalysts, we found different apparent activation energies () depending on the feedwater pressure. This is partially attributed to changing numbers of metal-support interface (MSI) sites as water coverage changes with temperature. Constant water coverage studies showed two kinetic regim…
Publication
ID32179374Published Date2020-03-05JournalBiophysical chemistry, 2020-03-05, Volume 260
The membrane binding behaviors of beta-amyloid fibrils, dimers to pentamers, from solution to lipid raft surfaces, were investigated using coarse-grained (CG) MD simulations. Our CG rafts contain phospholipid, cholesterol (with or without tail- or headgroup modifications), and with or without asymmetrically distributed monosialotetrahexosylganglioside (GM1). All rafts exhibited liquid-ordered (Lo), liquid-disordered (Ld), and interfacial Lo/Ld (Lod) domains, with domain sizes depending on cho…
Publication
ID32129723Published Date2020-03-04JournalEating disorders, 2020-03-04
The primary aim of this study was to investigate self-reported reasons for engaging in dietary restraint (DR) in a food insecure urban population. It also tested whether DR was associated with increased eating disorder (ED) pathology when DR was broadly assessed. The initial sample ( = 503) consisted of adult clients visiting food pantries who completed the , the , and three items from the DR subscale of ); EDE-Q items were modified to allow participants to explain why they restricted. Analys…
Publication
ID31377916Published Date2020-03-01JournalJournal of gambling studies, 2020-03-01, Volume 36
Prediction and wager on the outcome of games/matches are known as sports betting. Positive attitudes toward sports betting may, in the long run, predict sports betting behavior and gambling-related problems. This study, therefore, examined the influence of gender, age, sports betting knowledge and peer-based gambling on attitudes toward sports betting among young adults in Nigeria. The ex-post facto design was adopted in this cross-sectional survey. The participants were 749 students (42.9% f…
Publication
IDDOI:10.2308/acch-52636Published Date2020-03-01JournalAccounting Horizons, 2020-03-01, Volume 34
SYNOPSIS The sentinel effect posits that the perception of increased oversight is associated with improved behavior. We consider the association between enhanced government oversight and financial reporting aggressiveness in the healthcare industry. Specifically, we examine the association between criminal cases (pending cases and successful cases) against healthcare providers and the quality of subjective accounts that require significant judgment and have been shown to be linked to healthca…
Publication
ID32109925Published Date2020-02-27JournalHealth care management review, 2020-02-27
Local multihospital systems (LMSs) commonly struggle to effectively coordinate across system members. Although a recent taxonomy of LMSs found the majority of systems to display lower levels of differentiation, integration, and coordination, some categories of LMS forms exhibited higher levels of integration and coordination.This study examines organizational and environmental factors associated with LMS forms displaying higher levels of integration and coordination.Applying a multitheoretica…
Publication
ID32075680Published Date2020-02-19JournalClinical epigenetics, 2020-02-19, Volume 12
Obesity and diabetes mellitus are directly implicated in many adverse health consequences in adults as well as in the offspring of obese and diabetic mothers. Hispanic Americans are particularly at risk for obesity, diabetes, and end-stage renal disease. Maternal obesity and/or diabetes through prenatal programming may alter the fetal epigenome increasing the risk of metabolic disease in their offspring. The aims of this study were to determine if maternal obesity or diabetes mellitus during …
Publication
ID31941272Published Date2020-02-18JournalAnalytical chemistry, 2020-02-18, Volume 92
The formation of gelatinous networks within an aerosol particle significantly alters the physicochemical properties of the aerosol material. Existing techniques for studying gel transitions rely on bulk rheometry, which is limited by contact with the sample, or microrheological techniques such as holographic optical tweezers, which rely on expensive equipment and high-powered lasers that can degrade light-absorbing aerosol. Here, we present a new technique to probe the microrheological charac…
We found 1,480 documents that match your Search
Research Grants: 296
Publications: 1,178
Patents: 4
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