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Research Institution (254)Company (111)University (18)Investor (4)Foundation (2)
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Patent
Publication NumberUS 10634684Filing StatusIssued PatentAvailabilityLicensableFiling Date2014-11-13Publication Date2020-04-28
An object of the present invention is to provide a method for efficiently identifying a polyubiquitinated substrate which is generally not easily identified. The method for identifying a polyubiquitinated substrate includes (1) a step of expressing a trypsin-resistant polyubiquitin chain-binding protein and a ubiquitin ligase in a cell, (2) a step of isolating a complex that contains the trypsin-resistant polyubiquitin chain-binding protein from the cell having undergone the step (1), (3) a s…
Patent
Publication NumberUS 10632187Filing StatusIssued PatentAvailabilityUnknownFiling Date2019-05-03Publication Date2020-04-28
Disclosed is a hemagglutinin-binding peptide producing an anti-influenza virus effect higher than that of existing peptides. Also disclosed are hemagglutinin-binding peptides comprising a polypeptide having any of the following amino acid sequences (i) to (iv): (i) Thr-MeGly-Asp-MePhe-MePhe-Ser-MeSer-His-Tyr-Thr-Val-Pro-Arg (SEQ ID NO: 1); (ii) Arg-Val-Ser-MePhe-Thr-Tyr-MePhe-MeSer-Tyr-Thr-Pro-Ser (SEQ ID NO: 2); (iii) an amino acid sequence with deletions, additions, or substitutions of one …
Patent
Publication NumberUS 20200032222Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-03-27Publication Date2020-01-30
Provided is a host cell for stably propagating a virulent hand, foot and mouth disease virus, the host cell expressing no heparan sulfate and overexpressing primate scavenger receptor class B member 2 (SCARB2). Also provided is a method for screening for an anti-hand, foot and mouth disease virus vaccine or an anti-hand, foot and mouth disease virus drug using a stably cultured virulent hand, foot and mouth disease virus.
Patent
Publication NumberUS 20190335724Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-03-23Publication Date2019-11-07
The present invention provides a mouse with liver damage, having a high degree of damage against the mouse's original hepatocytes while having a uPA gene in a heterozygous form, and a method for efficiently preparing the mouse. Specifically, the method for preparing a mouse with liver damage having the uPA gene in a heterozygous form comprises the following steps of: (i) transforming mouse ES cells with a DNA fragment containing a liver-specific promoter/enhancer and cDNA that encodes a uroki…
Clinical Trial
Clinical Trial IDWHO:JPRN-UMIN000038189Start Date2019-10-03Completion Date2020-03-31PhaseN/AStudy TypeObservationalStatusRecruiting
Clinical Trial
Clinical Trial IDWHO:JPRN-UMIN000038507Start Date2019-10-01Completion Date2024-03-31PhaseN/AStudy TypeObservationalStatusPending
Patent
Publication NumberEP 3538211 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-11-10Publication Date2019-09-18
Patent
Publication NumberUS 20190262613Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-11-10Publication Date2019-08-29
Modulation of neural activity in the superior laryngeal nerve (SLN) or cervical sympathetic trunk (CST) is effective in treating diseases and conditions mediated by thyroid and parathyroid hormones, in particular diseases associated with calcitonin secretion (e.g. osteoporosis) or diseases associated with thyroxine secretion (e.g. hypothyroid syndrome).
We found 254 documents that match your Search
Patents: 183
Clinical Trials: 38
Web Documents: 33

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