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IDDOI:10.1093/jmammal/gyaa040Published Date2020-05-05JournalJournal of Mammalogy, 2020-05-05
Abstract Despite the presence of mostly endemic species, the most comprehensive data set on the distribution and ecology of small mammals inhabiting Simien Mountains National Park (SMNP) dated from 1927. The study we carried out and report here provides a unique opportunity to assess the possible role of climate change over the last 88 years on the elevational distribution of mammals in the Ethiopian highlands. Between September and November 2015, three of us (EWC, WTS, YM) collected nonvolan…
Publication
ID32279487Published Date2020-05-04JournalInorganic chemistry, 2020-05-04, Volume 59
Stable coordination complexes of Ti (3d) are relatively uncommon, but are of interest as synthons for low oxidation state titanium complexes for application as potential catalysts and reagents for organic synthesis. Specifically, high-spin Ti ions supported by redox-inactive ligands are still quite rare due to the reducing power of this soft ion. Among such Ti complexes is -[TiCl(tmeda)], where tmeda = ,,','-tetramethylethane-1,2-diamine. This complex was first reported by Gambarotta and co-w…
Publication
ID31218537Published Date2020-05-01JournalInternational microbiology : the official journal of the Spanish Society for Microbiology, 2020-05-01, Volume 23
A novel group of agents known as the indole-2-carboxamides (often referred to as indoleamides) have been shown to demonstrate high antimycobacterial activity. Studies have demonstrated that the best indoleamides possess desirable ADME/Tox properties, with less adverse effects and increased efficacy against both MDR-TB (multi-drug resistant TB) and XDR-TB (extensively drug-resistant TB). The primary mechanism of killing Mycobacterium tuberculosis (Mtb) by indoleamides is by disrupting the func…
Publication
ID32041716Published Date2020-04-21JournalAntimicrobial agents and chemotherapy, 2020-04-21, Volume 64
New drugs or therapeutic combinations are urgently needed against Previously, we demonstrated the potent activity of indole-2-carboxamides 6 and 12 against We show here that these compounds act synergistically with imipenem and cefoxitin and increase the bactericidal activity of the β-lactams against In addition, compound 12 also displays synergism with imipenem and cefoxitin within infected macrophages. The clinical potential of these new drug combinations requires further evaluation.
Publication
ID32215841Published Date2020-03-25JournalQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020-03-25
Results examining associations between metabolic syndrome (MetS) and depression, as well as on quality of life (QoL), are inconsistent. We aimed to determine whether individuals with MetS had decreased mental health-related QoL (MH-QoL) and higher frequency of depressive symptoms.Data from 1,015 participants from the Fels Longitudinal Study were analyzed (mean age ± SD: 49.6 ± 18.7 years, 29.3% MetS, 51% females). MetS was determined using American Heart Association/National Heart, Lung, and …
Publication
IDDOI:10.1177/1078087418802359Published Date2020-03-01JournalUrban Affairs Review, 2020-03-01, Volume 56
What factors do administrators consider when (dis)investing in public facilities? We model school closure decisions in Chicago from 2003 to 2013 with multinomial logit models that estimate the decision to close or “turnaround” schools as a function of building, student, geographic, political, and neighborhood factors during two mayoral administrations. The results from our specifications validate the “official” rationale for closures and turnarounds: Low test scores are associated with closur…
Publication
ID31816395Published Date2020-03-01JournalMolecular phylogenetics and evolution, 2020-03-01, Volume 144
Wood mice of the genus Hylomyscus, are small-sized rodents widely distributed in lowland and montane rainforests in tropical Africa, where they can be locally abundant. Recent morphological and molecular studies have increased the number of recognized species from 8 to 18 during the last 15 years. We used complete mitochondrial genomes and five nuclear genes to infer the number of candidate species within this genus and depict its evolutionary history. In terms of gene sampling and geographic…
Publication
ID31860799Published Date2020-02-14JournalACS infectious diseases, 2020-02-14, Volume 6
The prevalence of pulmonary infections due to nontuberculous mycobacteria such as has been increasing and surpassing tuberculosis (TB) in some industrialized countries. Because of intrinsic resistance to most antibiotics that drastically limits conventional chemotherapeutic treatment options, new anti- therapeutics are urgently needed against this emerging pathogen. Extensive screening of a library of benzimidazole derivatives that were previously shown to be active against led to the identif…
Publication
ID31756558Published Date2020-02-01JournalJournal of inorganic biochemistry, 2020-02-01, Volume 203
Zinc centers in pseudo-tetrahedral geometry are widely found in biology, often with three histidine ligands from protein. The trispyrazolylborate "scorpionate" ligand is used as a model for this tris(histidine) motif, and spectroscopically active Co is often used as a substitute for spectroscopically silent Zn. In this work, four pseudo-tetrahedral scorpionate complexes with the formula (Tp)CoL, where Tp = hydrotris(3-tert-butyl, 5-2'-thienyl-pyrazol-1-yl)borate anion and L = Cl, N, NCO, or N…
Publication
ID31863266Published Date2020-02-01JournalArchives of virology, 2020-02-01, Volume 165
The aim of this work was the genetic typing of RVA isolates originating from pigs and human patients in Slovakia. Seventy-eight rectal swabs from domestic pigs and 30 stool samples from humans were collected. The whole VP7 (G genotypes), VP6 (I genotypes) and partial VP4 (P genotypes) ORFs were amplified by RT-PCR. Genetic variability was higher amongst porcine sequences, where four G genotypes (G3, G4, G5, G11), two P genotypes (P[6], P[13]) and one I5 genotype were detected. Human RVA strai…
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