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Patent
Publication NumberUS 10561735Filing StatusIssued PatentAvailabilityUnknownFiling Date2017-11-20Publication Date2020-02-18
The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particu…
Patent
Publication NumberUS 10472394Filing StatusIssued PatentAvailabilityUnknownFiling Date2017-08-14Publication Date2019-11-12
The invention is directed to isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A. The mixtures possess enhanced efficacy and reduced toxicity over the individual isomers and over naturally occurring and other presently known cyclosporines and cyclosporine derivatives. Embodiments of the present invention are directed toward cis and trans-isomers of cyclosporin A analogs referred to as ISATX247, and derivatives thereof. Mixtures of ISATX247 isomers exhib…
Patent
Publication NumberBR PI315657 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2003-10-27Publication Date2018-09-11
"formulação de dosagem sólida, comprimido para liberação controlada, método de fabricar uma medicação de liberação controlada, composição farmacêutica e uso de uma composição". formulação de dosagem sólida tendo um núcleo com um agente farmacológico dispersado em uma primeira matriz de liberação controlada, a partir da qual a liberação do agente é relativamente lenta; e um revestimento formado sobre o núcleo e tendo o agente dispersado em uma segunda matriz de liberação controlada, a partir d…
Patent
Publication NumberUS 20180193466Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-10-12Publication Date2018-07-12
The invention provides starch-based microparticles with high loading capacity for the stabilization and/or controlled release of one or more agents, for example, a pharmaceutical, a taste masking agent, a flavoring agent, or a combination thereof, disposed within the microparticles, and to methods of making and using such microparticles.
Patent
Publication NumberUS 20180185289Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-09-11Publication Date2018-07-05
Disclosed is a misuse preventative, controlled release composition in the form of a multilayered oral dosage form. A first layer contains a plurality of controlled release microparticles having a pharmaceutically active agent (for example, an opioid analgesic) disposed therein. The second layer, which can be adjacent the first layer comprises a pharmaceutically active agent that can be the same or different from the pharmaceutically active agent in the microparticles in the first layer. The c…
Patent
Publication NumberUS 20180185292Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-09-11Publication Date2018-07-05
Disclosed is a misuse preventative, controlled release formulation comprising a core comprising a superabsorbent material (for example, polycarbophil), a controlled release coat surrounding the core, and a plurality of controlled release microparticles having a pharmaceutically active agent (for example, an opioid analgesic) disposed within the core, the coat, or both the core and the coat. When crushed, either intentionally or accidentally, and exposed to an aqueous medium, the superabsorben…
Patent
Publication NumberES 2643576 T3Filing StatusOtherAvailabilityUnknownFiling Date2009-06-05Publication Date2017-11-23
Patent
Publication NumberUS 9765119Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-11-23Publication Date2017-09-19
The invention is directed to isomeric mixtures of cyclosporine analogs that are structurally similar to cyclosporine A. The mixtures possess enhanced efficacy and reduced toxicity over the individual isomers and over naturally occurring and other presently known cyclosporines and cyclosporine derivatives. Embodiments of the present invention are directed toward cis and trans-isomers of cyclosporin A analogs referred to as ISATX247, and derivatives thereof. Mixtures of ISATX247 isomers exhibit…
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Patents: 168
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