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SEC Filing
Accession Number0001533914-20-000001Form TypeDAcceptance Date2020-03-06
Sold $1,000,000 of $2,000,000 of Debt and Other
Patent
Publication NumberEP 3148540 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-05-27Publication Date2019-12-25
Patent
Publication NumberEP 3578179 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2015-05-27Publication Date2019-12-11
A thioester compound of Formula (XXV) is described: or a pharmaceutically acceptable salt thereof, wherein X, Y, Z, R1-R14 are defined herein. The compounds are useful in medicine, for example for use in the treatment of a disorder mediated by inhibition of histone deacetylase.
Patent
Publication NumberTW 201940498 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2015-05-27Publication Date2019-10-16
Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
SEC Filing
Accession Number0001533914-19-000002Form TypeDAcceptance Date2019-09-20
Sold $100,000 of $2,000,000 of Debt and Other
Patent
Publication NumberJP 2019142868 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2019-03-12Publication Date2019-08-29
To provide substituted cyclic depsipeptides and a process for preparation thereof.SOLUTION: The invention provides a thioester compound represented by formula (XXV) or a pharmaceutically acceptable salt thereof. In the formula, each pair of Rand R, Rand R, Rand R, and Rand Ris independently selected from the group consisting of H, C-Calkyl and C-Ccycloalkyl, or together forms a C-Ccycloalkyl or C-Cheterocycloalkyl.SELECTED DRAWING: None
Patent
Publication NumberCN 110156874 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2015-05-27Publication Date2019-08-23
Cyclic depsipeptides of Formula (XXV) or pharmaceutically acceptable salts thereof are described, wherein R1 to R6 and R13 to R14 are defined in the specification. The compounds or the pharmaceutically acceptable salts thereof can be used for treating diseases mediated by histone deacetylase dysregulation, such as cancer, inflammatory diseases, autoimmune diseases, allergic diseases, and central nervous system diseases.
Patent
Publication NumberCN 106456613 BFiling StatusIssued PatentAvailabilityUnknownFiling Date2015-05-27Publication Date2019-07-09
A thioester compound of Formula (XXV) is described:or a pharmaceutically acceptable salt thereof, wherein X, Y, Z, R1-R14are defined herein. The compounds are useful in medicine, for example for use in the treatment of a disorder mediated by inhibition of histone deacetylase.
Patent
Publication NumberUS 20190177372Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-09-11Publication Date2019-06-13
Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
Patent
Publication NumberIL 263159 D0Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-11-20Publication Date2018-12-31
The present invention provides a novel macrocyclic prodrug compound of general Formula (I), a pharmaceutical composition comprising a compound of Formula (I), and a method for treating diseases mediated by HDAC enzymes by administering a compound of Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, A and Z are defined herein.
We found 23 documents that match your Search
Patents: 16
Clinical Trials: 1
SEC Filings: 6

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