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Research Grant
Award Number2011800Funding AgencyNational Science FoundationEffective Date2020-08-01Expiration Date2023-07-31Funding Amount$399,331
The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP), through Targeted Infusion Projects, supports the development, implementation, and study of evidence-based innovative models and approaches for improving the preparation and success of HBCU undergraduate students so that they may pursue STEM graduate programs and/or careers. North Carolina Central University (NCCU) intends to enhance its nuclear science capabilities for the purpose of producing innovative researc…
Publication
ID32447509Published Date2020-08-01JournalNeurochemical research, 2020-08-01, Volume 45
Selenium has been shown to possess antioxidant and neuroprotective effects by modulating mitochondrial function and activating mitochondrial biogenesis. Our previous study has also suggested that selenium protected neurons against glutamate toxicity and hyperglycemia-induced damage by regulating mitochondrial fission and fusion. However, it is still not known whether the mitochondrial biogenesis is involved in selenium alleviating hyperglycemia-aggravated cerebral ischemia reperfusion (I/R) i…
Publication
ID32720665Published Date2020-07-28JournalNanoscale, 2020-07-28
Recently, a zipper two-dimensional (2D) material Bi2O2Se belonging to the layered bismuth oxychalcogenide (Bi2O2X: X = S, Se, Te) family, has emerged as an alternate candidate to van der Waals 2D materials for high-performance electronic and optoelectronic applications. This hints towards exploring the other members of the Bi2O2X family for their true potential and bismuth oxysulfide (Bi2O2S) could be the next member for such applications. Here, we demonstrate for the first time, the scalable…
Publication
ID32660355Published Date2020-07-27JournalEpigenetics, 2020-07-27
Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with signalling pathways to also affect prostate tumour progression and is additionally associated with decreased DNA methylation. The expression of , methyltransferases, and was assessed in prostate cancer cells (LNCaP) treated with EGF, an EGFR inhibitor…
Publication
ID32348856Published Date2020-08-15JournalInternational journal of biological macromolecules, 2020-08-15, Volume 157
Plant-based expression system has many potential advantages to produce biopharmaceuticals, but plants cannot be directly used to express human glycoproteins because of their differences in glycosylation abilities from mammals. To exploit plant-based expression system for producing recombinant human erythropoietin (rhuEPO), we glycoengineered tobacco plants by stably introducing seven to eight mammalian genes including a target human EPO into tobacco in order to generate capacities for β1,4-ga…
Publication
ID32705914Published Date2020-07-23JournalBrain injury, 2020-07-23
This study determined whether initial GCS score, head CT results, cognitive performance on IMPACT testing, or APOE genotype most effectively predicted 1-month functional outcome after mild traumatic brain injury (mTBI). This study tested the hypotheses that participants with poor performance on initial cognitive testing and those with an APOEe4 genotype would exhibit a poorer 1-month recovery after mTBI.Regression analysis determined which independent variables were most effective in predicti…
Publication
IDDOI:10.1044/2020_persp-19-00112Published Date2020-07-22JournalPerspectives of the ASHA Special Interest Groups, 2020-07-22
Purpose Patient-centered care is a healthcare approach that values an individual's right to make health care choices. For patients with dysphagia, honoring choices that carry significant health risks is challenging. This article presents strategies adapted from the multicultural literature to enhance patient engagement and help balance choices for quality of life while mitigating potential negative health consequences. The goal is to provide clinicians with knowledge gleaned from multicultura…
Publication
IDDOI:10.1142/s0217984920400618Published Date2020-07-20JournalModern Physics Letters B, 2020-07-20, Volume 34
The main goal of our research is to find the connection between micro particles and microorganisms motion in the Nature, considered as Brownian’s Motion within the fractal’s nature. For ceramics and generally material science it is important to clarify the particles motion and other phenomena, especially for grains and pores. Our idea is to establish control over the relation order–disorder on particle motion and their collision effects by Brownian motion phenomena in the frame of fractal nat…
Publication
ID32652035Published Date2020-07-11JournalEndocrinology, 2020-07-11
Mitochondria play important roles in ovarian follicle development. Mitochondrial dysfunction, including mitochondrial gene deficiency, impairs the ovarian development. Here, we explored the role and mechanism of mitochondrial inner membrane gene Immp2l in ovarian follicle growth and development. Our results revealed that the female Immp2l-/- mice were infertile, while the Immp2l+/- mice were normal. Body and ovarian weights were reduced in the female Immp2l-/- mice, ovarian follicle growth an…
Publication
ID32654437Published Date2020-07-08JournalInternational journal of health policy and management, 2020-07-08
Allocation of adequate healthcare facilities is one of the most important factors that public health policymakers consider when preparing for infectious disease outbreaks. Negative pressure isolation rooms (NPIRs) are one of the critical resources for control of infectious respiratory diseases, such as the novel coronavirus disease 2019 (COVID-19) outbreak. However, there is insufficient attention to efficient allocation of NPIR-equipped hospitals.We aim to explore any insufficiency and spati…
We found 1,905 documents that match your Search
Research Grants: 731
Publications: 1,129
Patents: 33
Clinical Trials: 1
Web Documents: 11

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