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Patent
Publication NumberUS 20100168120Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-27Publication Date2010-07-01
The invention relates to stable and substantially purified synthetic pharmaceutically acceptable acid addition salts of pyridazine compounds of the formula I wherein R10 is hydrogen, hydroxyl, alkyl, alkoxy, alkenyl, alkynyl, alkylene, aryl, heteroaryl, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, halo, =0, ═S, carboxyl, carbonyl, carbamoyl, carboxamide, or phosphonate, and R11 is alkyl, alkoxy, alkenyl, alkynyl, alkylene, alkenylene…
Patent
Publication NumberCN 101754762 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-27Publication Date2010-06-23
The invention relates to chemical compounds, compositions and methods of making and using the same. In particular, the invention provides selected pyridazine compounds of the formula (I) are independently hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, alkylene, alkenylene, alkoxy, alkenyloxy, cycloalkyl, cycloalkenyl, cycloalkynyl, cycloalkoxy, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, ha…
Patent
Publication NumberCN 100462099 CFiling StatusIssued PatentAvailabilityUnknownFiling Date2005-04-08Publication Date2009-02-18
Patent
Publication NumberWO 2007130383 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-27Publication Date2007-11-15
The invention relates to compositions, conjugates and methods comprising pyridazine compounds and secretase inhibitors for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
Patent
Publication NumberWO 2007127448 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-27Publication Date2007-11-08
The invention relates to stable and substantially purified synthetic pharmaceutically acceptable acid addition salts of pyridazine compounds of the formula I wherein R10 is hydrogen, hydroxyl, alkyl, alkoxy, alkenyl, alkynyl, alkylene, aryl, heteroaryl, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, halo, =0, =S, carboxyl, carbonyl, carbamoyl, carboxamide, or phosphonate, and R11 is alkyl, alkoxy, alkenyl, alkynyl, alkylene, alkenylene…
Patent
Publication NumberWO 2007127375 A2Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2007-04-27Publication Date2007-11-08
The invention relates to chemical compounds, compositions and methods of making and using the same. In particular, the invention provides selected pyridazine compounds of the formula I wherein R1, R4, R5, R6, R7, R8, R9, R12, R13 ET R14 are independently hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, alkylene, alkenylene, alkoxy, alkenyloxy, cycloalkyl, cycloalkenyl, cycloalkynyl, cycloalkoxy, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, amino, imino, azido, thiol,…
Patent
Publication NumberCN 1492765 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2001-11-29Publication Date2004-04-28
本发明涉及用于预防和治疗痴呆的草药组合物,它包括代替常规草药组合物中人参的何首乌(何首乌)、远志(小扁豆)、丁香(丁香)和姜(姜)以便以最低的用量达到最大的抗痴呆作用。
Patent
Publication NumberEP 1357923 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2001-11-29Publication Date2003-11-05
Patent
Publication NumberKR 100360674 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2001-11-21Publication Date2002-11-13
본 발명은 치매예방 및 치료제 조성물에 관한 것으로서, 더욱 상세하게는 종래 생약제로 구성된 치매치료용 조성물 중에서 주요성분을 새롭게 구성하여 종래 주성분으로 사용되어 왔던 인삼을 사용하지 아니하고 하수오를 사용하며 그 이외의 다른 성분들도 최적화 하는 함량으로 새롭게 조성하여 종래 제품에 비하여 부작용을 크게 줄이고, 약리학적, 임상학적 효능을 월등히 향상시켜서 치매효능을 극대화시킬 수 있을 뿐만 아니라 독성을 최소화하여 특히 노인성 치매에 탁월한 효과를 가지는 새로운 구성의 치매 예방 및 치료제 조성물에 관한 것이다.
Patent
Publication NumberWO 2062366 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2001-11-29Publication Date2002-08-15
The present invention relates to herbal composition for the prevention and treatment of dementia comprising Polygoni multiflori Radix(Polygonum multiflorum Thunberg), instead of ginseng, Polygalae Radix (Polygala tatarinowi Regel), Caryophylli Flos (Eugenie caryophyllata Thunberg), and Zingibreis Rhizoma (Zingiber officinale Rosc.) in the conventional herbal composition to maximize anti-dementia effect with minimized amount.
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