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Patent
Publication NumberUS 7638519StatusIssued PatentAvailabilityUnknownFiling Date2004-12-21Publication Date2009-12-29
The present invention provides certain compounds, pharmaceutical formulations thereof, and methods for the treatment of conditions mediated by 5-HT2 receptors. These compounds provide for modulation of the signals mediated by 5-HT2 receptors, specifically those receptors in the cardiovascular system. Thus, these compounds may be used alone or in conjunction with other drugs to treat cardiovascular diseases such as, but not limited to, muscle atrophy, cardiac hypertrophy, heart failure, and pr…
Patent
Publication NumberUS 7629308StatusIssued PatentAvailabilityUnknownFiling Date2001-02-13Publication Date2009-12-08
The present invention relates to the polypeptides known as muscle calcineurin interacting proteins (MCIPs). These molecules binding to calcineurin and, in so doing, modulate its functions, which includes phosphate removal as part of a pathway coupling Ca2+ to cellular responses in muscle. MCIPs form a physical complex with the catalytic subunit of calcineurin, and increased levels of MCIPs correspond to a reduced ability of calcineurin to stimulate transcription of certain target genes. Metho…
Patent
Publication NumberUS 7485653StatusIssued PatentAvailabilityUnknownFiling Date2004-11-03Publication Date2009-02-03
The present invention provides certain substituted 1,4-dihydropyridine compounds, including pure enantiomeric forms and pharmaceutical formulations thereof. These compounds provide for elevation of α-MyHC protein levels and α-MyHC mRNA levels, and most frequently these same compounds provide simultaneous lowering of β-MyHC protein levels and β-MyHC mRNA levels. Thus, these compounds may be used alone or in conjunction with other drugs to treat heart failure.
Patent
Publication NumberUS 7482331StatusIssued PatentAvailabilityLicensableFiling Date2000-04-25Publication Date2009-01-27
The invention provides a method of treating myocardial failure in a human. The method comprises administering an effective amount of transgene encoding α-MHC that directly causes an increase in the quantity of α-MHC in the myocardial tissue of the heart.
Patent
Publication NumberDE 602004016547 D1StatusOtherAvailabilityUnknownFiling Date2004-11-03Publication Date2008-10-23
Patent
Publication NumberAT 407925 TStatusOtherAvailabilityUnknownFiling Date2004-11-03Publication Date2008-09-15
Patent
Publication NumberEP 1685107 B1StatusIssued PatentAvailabilityUnknownFiling Date2004-11-03Publication Date2008-09-10
Patent
Publication NumberDE 602004015321 D1StatusOtherAvailabilityUnknownFiling Date2004-11-03Publication Date2008-09-04
Patent
Publication NumberEP 1962888 A2StatusPatent ApplicationAvailabilityUnknownFiling Date2006-11-17Publication Date2008-09-03
Patent
Publication NumberAT 402147 TStatusOtherAvailabilityUnknownFiling Date2004-11-03Publication Date2008-08-15
We found 94 documents that match your Search
Patents: 94
Clinical Trials: 1
SEC Filings: 74

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