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Patent
Publication NumberEP 2443432 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2010-06-18Publication Date2018-09-05
Patent
Publication NumberUS 8431888Filing StatusIssued PatentAvailabilityUnknownFiling Date2010-06-18Publication Date2013-04-30
Droplets or plugs within multiphase microfluidic systems have rapidly gained interest as a way to manipulate samples and chemical reactions on the femtoliter to microliter scale. Chemical analysis of the plugs remains a challenge. It has been discovered that nanoliter plugs of sample separated by air or oil can be analyzed by electrospray ionization mass spectrometry when pumped directly into a fused silica nanospray emitter nozzle. Using leu-enkephalin in methanol and 1% acetic acid in water…
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