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Publication
ID31373939Published Date2020-03-01JournalJournal of clinical gastroenterology, 2020-03-01, Volume 54
The goal of this study was to evaluate the impact of obesity on the outcomes of patients with lower gastrointestinal hemorrhage (LGIH).Obesity is considered as an independent risk factor for LGIH. We sought to analyze in-hospital outcomes and characteristics of nonobese and obese patients who presented with LGIH, and further, identify resource utilization during their hospital stay.With the use of National Inpatient Sample from January 2005 through December 2014, LGIH-related hospitalizations…
Publication
ID32057261Published Date2020-03-01JournalAdvances in physiology education, 2020-03-01, Volume 44
In conventional team-based learning (TBL), readiness assurance test (RAT) items must be formatted as free-standing multiple-choice questions (MCQs). Even in the application phase of TBL, all teams must work on the same, significant problem and be required to make a specific choice and simultaneously report them to the whole class, which the MCQ format with predetermined answer choices allows. However, the founders of the TBL method rightly emphasize that the intended learning outcomes of a co…
Publication
ID31812336Published Date2020-03-01JournalThe Journal of surgical research, 2020-03-01, Volume 247
The American Board of Surgery In-training Examination (ABSITE) is an important marker of medical knowledge. It is unclear what factors predict or improve these scores. We evaluated demographics, United States Medical Licensing Examination (USMLE) step 1 and 2 scores, and surgical rotations during the intern year to determine if there were any correlations with the ABSITE performance.This was a multicenter retrospective review during a 6-y period, investigating the correlation and association …
Publication
ID31715332Published Date2020-03-01JournalComputer methods and programs in biomedicine, 2020-03-01, Volume 185
In most patients presenting with respiratory symptoms, the findings of chest radiography play a key role in the diagnosis, management, and follow-up of the disease. Consolidation is a common term in radiology, which indicates focally increased lung density. When the alveolar structures become filled with pus, fluid, blood cells or protein subsequent to a pulmonary pathological process, it may result in different types of lung opacity in chest radiograph. This study aims at detecting consolida…
Publication
ID31559914Published Date2020-02-15JournalStem cells and development, 2020-02-15, Volume 29
Although research involving traumatic brain injury (TBI) has traditionally focused on the acute clinical manifestations, new studies provide evidence for chronic and progressive neurological sequelae associated with TBI, highlighting the risk of persistent, and sometimes life-long, consequences for affected patients. Several treatment modalities to date have demonstrated efficacy in experimental models. However, there is currently no effective treatment to improve neural structure repair and …
Publication
ID29635530Published Date2020-02-14JournalThe journals of gerontology. Series B, Psychological sciences and social sciences, 2020-02-14, Volume 75
We evaluated the association between cumulative stressful life events (SLE) and type of stress (lifetime vs recent) and incident diabetes (Type 2 diabetes mellitus [T2DM]) in middle-aged U.S. adults.Data from the 2006-2014 waves of the Health and Retirement Study (HRS) were analyzed (n = 7,956). Stress-related differences in age at T2DM diagnosis were estimated using Cox proportional hazards models.The adjusted risk of T2DM significantly increased by 6% per unit increase in cumulative SLE (95…
Publication
ID32049021Published Date2020-02-11JournalCell reports, 2020-02-11, Volume 30
Mesenchymal stromal cell (MSC)-based therapy for inflammatory diseases involves paracrine and efferocytotic activation of immunosuppressive interleukin-10 (IL-10) macrophages. The paracrine pathway for MSC-mediated IL-10 macrophage functionality and response to tissue injury is not fully understood. In our present study, clodronate pre-treatment of colitic mice confirms the essential role of endogenous macrophages in bone-marrow-derived MSC (BM-MSC)-mediated clinical rescue of dextran sulfate…
Publication
ID31780266Published Date2020-02-05JournalBiochemical and biophysical research communications, 2020-02-05, Volume 522
HE4 (Human Epididymis Protein 4) encoded by the wfdc2 gene was first identified as a highly expressed factor in human epididymis. HE4 expression levels in malignant lesions are correlated with the clinical manifestations of gynecologic cancers. HE4 serum test has been widely used for the triage of patients suspected of gynecologic cancers, prognosis of cancer patients, and monitoring cancer recurrence. While it is reported that HE4 may actively participate in the regulation of cancer cell pro…
Research Grant
Project Number1R15CA246552-01Funding AgencyNational Institutes of HealthEffective Date2020-02-03Expiration Date2023-01-31Funding Amount$424,500
Project Summary As the second leading cause of death in the US, cancer has a considerable impact of cancer on society, and a better understanding into the mechanisms of disease and potential therapeutics is needed. One proposed therapeutic target is the sumoylation pathway, which involves the post-translational modifications of proteins by the Small Ubiquitin-like Modifier (SUMO; sumoylation) and requires the SUMO-activating enzyme (SAE1/SAE2), the SUMO-conjugating enzyme (Ubc9), one of the f…
Publication
ID31758062Published Date2020-02-01JournalJournal of perinatology : official journal of the California Perinatal Association, 2020-02-01, Volume 40
To assess site variability and concomitant respiratory support related to the timing of caffeine discontinuation, and compare clinical characteristics of infants who discontinued caffeine before vs. within the last week of hospitalization.Cohort study of 81,110 infants
We found 1,786 documents that match your Search
Research Grants: 233
Publications: 1,482
Patents: 36
Clinical Trials: 35

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