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Research Grant
Project Number1R43HD102245-01Funding AgencyNational Institutes of HealthEffective Date2020-04-23Expiration Date2021-03-31Funding Amount$223,362
ABSTRACT Extracorporeal membrane oxygenation (ECMO) is becoming increasingly utilized to provide cardiopulmonary support in patients due to its versatility, immediate benefit, and relatively low cost. However, there continues to be significant morbidity and mortality related to hemostatic complications, especially in the neonatal and pediatric population. A few pediatric oxygenators are used in ECMO; however, all of these devices only have short term approval and are currently used off label …
Patent
Publication NumberEP 2396549 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2010-02-12Publication Date2019-10-23
Research Grant
Project Number2R44HD088243-02Funding AgencyNational Institutes of HealthEffective Date2019-08-01Expiration Date2020-07-31Funding Amount$725,223
ABSTRACT Extracorporeal membrane oxygenation (ECMO) use continues to increase as a supportive measure for cardio-respiratory failure. Pediatric patients with severe, acute left ventricular (LV) systolic dysfunction are often supported with venoarterial (VA) ECMO as a short-term bridge to recovery, transplant or a ventricular assist device (VAD). ECMO provides temporary gas exchange and increased cardiac output to end organs. Lack of egress of blood from the LV can lead to over-distension and …
Research Grant
Project Number5R44HL091606-06Funding AgencyNational Institutes of HealthEffective Date2018-04-01Expiration Date2020-03-31Funding Amount$822,319
? DESCRIPTION (provided by applicant): The use of ECMO in conjunction with CPR, a technique known as ECPR, has been shown to reduce central nervous system (CNS) damage, improve brain function after recovery, and result in survival-to-hospital- discharge rates up to 40%. A limiting factor for widespread adoption of ECPR is the need for a simple automatic perfusion system that is inherently safe, and provides full support with minimal operator intervention. Developed under SBIR funding (HL09161…
Patent
Publication NumberES 2658406 T3Filing StatusOtherAvailabilityUnknownFiling Date2014-09-09Publication Date2018-03-09
La bolsa (1) del tipo que comprende un cuerpo (2) de delimitación de un recinto de almacenamiento realizada a partir de un material laminar, una etiqueta (9) que se puede separar por completo de la bolsa al tirar y dispuesta, antes de su separación de la bolsa (1), de recubrimiento al menos parcial y coincidiendo con un principio de ruptura que forma, al menos en el cuerpo (2), una línea (6) cerrada para provocar, al tirar de la etiqueta (9), un desgarro del cuerpo (2), formando una abertura …
Patent
Publication NumberEP 3044116 B1Filing StatusIssued PatentAvailabilityUnknownFiling Date2014-09-09Publication Date2017-11-15
Research Grant
Project Number5R44HL091606-05Funding AgencyNational Institutes of HealthEffective Date2017-04-01Expiration Date2018-03-31Funding Amount$842,706
? DESCRIPTION (provided by applicant): The use of ECMO in conjunction with CPR, a technique known as ECPR, has been shown to reduce central nervous system (CNS) damage, improve brain function after recovery, and result in survival-to-hospital- discharge rates up to 40%. A limiting factor for widespread adoption of ECPR is the need for a simple automatic perfusion system that is inherently safe, and provides full support with minimal operator intervention. Developed under SBIR funding (HL09161…
Research Grant
Project Number1R43HD088243-01A1Funding AgencyNational Institutes of HealthEffective Date2016-09-19Expiration Date2019-07-31Funding Amount$209,536
ABSTRACT Extracorporeal membrane oxygenation (ECMO) use continues to increase as a supportive measure for cardio-respiratory failure. Pediatric patients with severe acute left ventricular (LV) systolic dysfunction are often supported with venoarterial (VA) ECMO as a short-term bridge to recovery, transplant or a ventricular assist device (VAD). Although this often provides the much needed temporary gas exchange and increase in cardiac output to all important end organs, lack of egress of bloo…
Research Grant
Project Number5R44HL114148-03Funding AgencyNational Institutes of HealthEffective Date2016-05-01Expiration Date2018-04-30Funding Amount$524,620
DESCRIPTION (provided by applicant): This proposal involves the incorporation of a proprietary nitric oxide (NO) releasing polymer material (NORL) into a venous catheter to reduce infection and clotting. Low levels of NO released by the normal endothelium inhibit platelet adhesion and activation, thus preventing thrombus formation. Further, it has been shown that NO at low doses exhibits significant bactericidal activity. Hence, the preparation of catheters that secrete NO will solve two long…
Research Grant
Project Number5R44HD078001-03Funding AgencyNational Institutes of HealthEffective Date2015-12-01Expiration Date2017-11-30Funding Amount$627,604
DESCRIPTION (provided by applicant): There are 5 million births in the United States each year of which 500,000 are premature. Prematurity is associated with substantial mortality, morbidity, and escalating cost. The complications of premature birth include respiratory, gastrointestinal, and central nervous system morbidity, and significant mortality. Many of these complications are caused, directly or indirectly, by our attempts to ventilate the immature lungs and reverse fetal circulation. …
We found 117 documents that match your Search
Research Grants: 85
Patents: 32

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