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Publication
ID31728798Published Date2020-06-01JournalJournal of community health, 2020-06-01, Volume 45
In artisanal fishing communities in Chile, the access to occupational safety and health (OSH) is limited by factors such as the informality of employment. Our objective was to analyze the working and health conditions of workers in a coastal town in Southern Chile, under a community-based participatory approach. We carried out two independent social dialogue workshops within the community. The first one (N of participants = 25) was aimed to identify the strengths, weaknesses and challenges fo…
Publication
ID32348699Published Date2020-06-01JournalPalliative medicine, 2020-06-01, Volume 34
Informal caregivers of palliative patients show higher levels of depression and distress compared with the general population. Fegg's (2013) existential behavioural therapy was shortened to two individual 1-h sessions (short-term existential behavioural therapy).Testing the effectiveness of sEBT on psychological symptoms of informal caregivers in comparison with active control.Randomised controlled trial.Informal caregivers of palliative in-patients.The primary outcome was depression; seconda…
Publication
ID32363546Published Date2020-06-01JournalArchives of gynecology and obstetrics, 2020-06-01, Volume 301
Nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors (COXibs) inhibit the progression of endometrial cancer, ovarian cancer and cervical cancer. However, concerning the adverse effects of NSAIDs and COXibs, it is still urgent and necessary to explore novel and specific anti-inflammation targets for potential chemoprevention. The signaling of cyclooxygenase 2-prostaglandin E-prostaglandin E receptors (COX-2-PGE-EPs) is the central inflammatory pathway involved in the gy…
Publication
ID32050799Published Date2020-06-01JournalHistory of psychiatry, 2020-06-01, Volume 31
Previous historiography has already paid particular attention to well-known 'metropolitan' biographies of I. Balinsky, V. Bekhterev and others, as well as their role in the establishment of a scientific approach in the treatment of mental illnesses in the Russian Empire. Little attention has been paid to 'provincial' physicians and the importance of their scientific activity in bridging the gap between the Russian and European institutions of psychiatry. The primary aim of this article is to …
Publication
ID32379884Published Date2020-06-01JournalThe Journal of cell biology, 2020-06-01, Volume 219
Cells navigating through complex tissues face a fundamental challenge: while multiple protrusions explore different paths, the cell needs to avoid entanglement. How a cell surveys and then corrects its own shape is poorly understood. Here, we demonstrate that spatially distinct microtubule dynamics regulate amoeboid cell migration by locally promoting the retraction of protrusions. In migrating dendritic cells, local microtubule depolymerization within protrusions remote from the microtubule …
Publication
ID31552495Published Date2020-06-01JournalEuropean archives of psychiatry and clinical neuroscience, 2020-06-01, Volume 270
In schizophrenia, decreased hippocampal volume, reduced oligodendrocyte numbers in hippocampal cornu ammonis (CA) subregions and reduced neuron number in the dentate gyrus have been reported; reduced oligodendrocyte numbers were significantly related to cognitive deficits. The hippocampus is involved in cognitive functions and connected to the hypothalamus, anterior thalamus, and cingulate cortex, forming the Papez circuit, and to the mediodorsal thalamus. The relationship between the volume …
Publication
IDDOI:10.1177/0957154x20901648Published Date2020-06-01JournalHistory of Psychiatry, 2020-06-01, Volume 31
Previous historiography has already paid particular attention to well-known ‘metropolitan’ biographies of I. Balinsky, V. Bekhterev and others, as well as their role in the establishment of a scientific approach in the treatment of mental illnesses in the Russian Empire. Little attention has been paid to ‘provincial’ physicians and the importance of their scientific activity in bridging the gap between the Russian and European institutions of psychiatry. The primary aim of this article is to …
Publication
ID32194093Published Date2020-06-01JournalJournal of pharmaceutical sciences, 2020-06-01, Volume 109
Understanding the formulation features that ensure sufficient stability during long-term storage is critical for developing next-generation therapeutic proteins. In this work, we investigate the physical stability of a bispecific antibody (Bis-mAb) in 12 different formulation conditions. Isothermal chemical denaturation with urea indicates a higher resistance to denaturant-induced unfolding when pH is increased from 5.0 to 6.5 but shows minor influence from the buffer type and ionic strength.…
Publication
ID32305380Published Date2020-06-01JournalJournal of dentistry, 2020-06-01, Volume 97
Long-term survival of two highly viscous glass ionomer cements (Fuji IX GP Fast and Equia Fil) over a period of 6 years in vivo.A total of 85 two- or three-surface class II restorations, comprising 43 Equia Fil / Equia Coat and 42 Fuji IX GP Fast / Fuji Coat LC, were placed in 34 patients. The restorations were re-evaluated after 6 years using the FDI criteria. The statistical analysis was performed with Fisher's exact test, the Wilcoxon signed-rank test, the Mann-Whitney U test and the Kapla…
Publication
ID31840876Published Date2020-06-01JournalJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2020-06-01, Volume 39
The scrotum may be affected by a plethora of different disorders such as infections, vasculopathies, trauma, and manifestations of primary and secondary malignant masses. In addition to the patient's medical history and clinical examination, ultrasound represents the imaging modality of choice to assess scrotal disorders. Time-consuming contrast-enhanced ultrasound and elastography can provide further information to distinguish between benign and malignant testicular mass lesions. The followi…
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Research Grants: 1,125
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Patents: 535
Clinical Trials: 341
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