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Patent
Publication NumberUS 10501803Filing StatusIssued PatentAvailabilityUnknownFiling Date2014-05-21Publication Date2019-12-10
The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a meth…
Publication
ID31809130Published Date2019-11-22JournalPhysical review letters, 2019-11-22, Volume 123
We report the first observation of D^{+}→τ^{+}ν_{τ} with a significance of 5.1σ. We measure B(D^{+}→τ^{+}ν_{τ})=(1.20±0.24_{stat}±0.12_{syst})×10^{-3}. Taking the world average B(D^{+}→μ^{+}ν_{μ})=(3.74±0.17)×10^{-4}, we obtain R_{τ/μ}=Γ(D^{+}→τ^{+}ν_{τ})/Γ(D^{+}→μ^{+}ν_{μ})=3.21±0.64_{stat}±0.43_{syst}., which is consistent with the standard model expectation of lepton flavor universality. Using external inputs, our results give values for the D^{+} decay constant f_{D^{+}} and the Cabibbo-K…
Publication
ID31685844Published Date2019-11-04JournalScientific reports, 2019-11-04, Volume 9
Transcriptional regulation of Laminin expression during embryogenesis is a key step required for proper ECM assembly. We show, that in Drosophila the Laminin B1 and Laminin B2 genes share expression patterns in mesodermal cells as well as in endodermal and ectodermal gut primordia, yolk and amnioserosa. In the absence of the GATA transcription factor Serpent, the spatial extend of Laminin reporter gene expression was strongly limited, indicating that Laminin expression in many tissues depends…
Publication
ID31585524Published Date2019-11-01JournalJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2019-11-01, Volume 31
Bcl-2, an anti-apoptotic protein, is commonly overexpressed in follicular lymphomas in humans. This is usually the result of a chromosomal translocation that transposes the gene into the immunoglobulin gene locus. The immunohistochemical assessment of this overexpression can be used as a tool for the differentiation of follicular lymphoma and follicular hyperplasia. In cats, little information about the expression of Bcl-2 in follicular lymphoma exists. We investigated 18 follicular lymphomas…
Patent
Publication NumberEP 3556731 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-04-19Publication Date2019-10-23
Die Erfindung betrifft ein effektives und kostengünstiges Verfahren zur chemischen Modifikation von Metalloxid-Oberflächen, insbesondere Partikeloberflächen und ganz besonders Metalloxid-Nanopartikel-Oberflächen. Das Verfahren umfasst die Vorbehandlung der Metalloxidoberfläche mit einem polar-protischen Lösungsmittel, die Abtrennung der Partikel bzw. Reinigung der MetalloxidOberfläche durch Zugabe eines polar-protischen Fällungs- bzw. Reinigungsmittel sowie die anschließende Durchführung der …
Patent
Publication NumberEP 3352196 B8Filing StatusIssued PatentAvailabilityUnknownFiling Date2017-01-20Publication Date2019-10-02
Publication
ID31633986Published Date2019-09-20JournalPhysical review letters, 2019-09-20, Volume 123
The exclusive process e^{+}e^{-}→ΛΛ[over ¯], with Λ→pπ^{-} and Λ[over ¯]→p[over ¯]π^{+}, has been studied at sqrt[s]=2.396 GeV for measurement of the timelike Λ electric and magnetic form factors, G_{E} and G_{M}. A data sample, corresponding to an integrated luminosity of 66.9 pb^{-1}, was collected with the BESIII detector for this purpose. A multidimensional analysis with a complete decomposition of the spin structure of the reaction enables a determination of the modulus of the ratio R=|G…
Publication
ID31573268Published Date2019-09-13JournalPhysical review letters, 2019-09-13, Volume 123
We present the first amplitude analysis of the decay D_{s}^{+}→π^{+}π^{0}η. We use an e^{+}e^{-} collision data sample corresponding to an integrated luminosity of 3.19 fb^{-1} collected with the BESIII detector at a center-of-mass energy of 4.178 GeV. We observe for the first time the W-annihilation dominant decays D_{s}^{+}→a_{0}(980)^{+}π^{0} and D_{s}^{+}→a_{0}(980)^{0}π^{+}. We measure the absolute branching fraction B(D_{s}^{+}→a_{0}(980)^{+(0)}π^{0^{(}+)},a_{0}(980)^{+(0)}→π^{+(0)}η)=(…
Patent
Publication NumberUS 20190262476Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2017-02-20Publication Date2019-08-29
The invention describes a new method for in vivo measurement and control of intraocular VEGF concentration using bioluminescence resonance energy transfer (BRET) of a VEGF-binding biosensor. Furthermore, the method is suitable for highly sensitive in vitro determination of VEGF concentration from a small sample volume.
Patent
Publication NumberEP 3530304 A1Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-02-26Publication Date2019-08-28
Die vorliegende Erfindung betrifft eine Kanüle, welche vorteilhaft zur Punktion des Glaskörpers eines menschlichen oder tierischen Auges geeignet ist. Ebenso ist die erfindungsgemäße Vorrichtung für die intravitreale Injektion eines Medikamentes in ein menschliches oder tierisches Auge geeignet.
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