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Patent
Publication NumberIL 187079 AStatusPatent ApplicationAvailabilityUnknownFiling Date2007-11-01Publication Date2015-06-30
Patent
Publication NumberEP 2314675 B1StatusIssued PatentAvailabilityUnknownFiling Date2006-05-03Publication Date2015-04-08
Patent
Publication NumberUS 8951768StatusIssued PatentAvailabilityUnknownFiling Date2011-07-11Publication Date2015-02-10
Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
Patent
Publication NumberKR 101476844 B1StatusIssued PatentAvailabilityUnknownFiling Date2006-05-03Publication Date2015-01-02
Patent
Publication NumberTW I465460 BStatusIssued PatentAvailabilityUnknownFiling Date2006-11-13Publication Date2014-12-21
The invention describes novel pharmaceutical compositions for the treatment of virus infections and cancer. The pharmaceutical compositions include mutant oligoadenylate synthetases (OAS) that have either enhanced cell permeability, reduced oxidative potential, improved antiviral activity, improved enzymatic activity, or absent enzymatic activity. The pharmaceutical compositions have improved drug properties and retain or have enhanced antiviral activity relative to their native forms. The ph…
Patent
Publication NumberKR 20140109510 AStatusPatent ApplicationAvailabilityUnknownFiling Date2006-05-03Publication Date2014-09-15
Modified amino acid sequences of OAS 1 proteins in non-human primates, and genes related thereto, are provided.
Patent
Publication NumberCN 103642898 AStatusPatent ApplicationAvailabilityUnknownFiling Date2006-05-03Publication Date2014-03-19
Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
Patent
Publication NumberTW I415944 BStatusIssued PatentAvailabilityUnknownFiling Date2005-02-05Publication Date2013-11-21
A method for detecting a mutation related to the gene encoding OAS 1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS 1, including antisense oligonucleotides, methods, and compositions specific for human OASI, are also provided.
Patent
Publication NumberIL 175089 AStatusPatent ApplicationAvailabilityUnknownFiling Date2006-04-23Publication Date2013-10-31
A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
Patent
Publication NumberCN 101627117 BStatusIssued PatentAvailabilityUnknownFiling Date2007-07-31Publication Date2013-10-30
We found 89 documents that match your Search
Research Grants: 5
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