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Publication
ID31301326Published Date2019-10-01JournalPhysiology & behavior, 2019-10-01, Volume 209
Steroids play an integral role in orchestrating embryonic development, and they can affect a suite of phenotypic traits, including learning and behavior. Endocrine disrupting compounds (EDCs) can alter steroid-dependent phenotypic traits during embryonic development. Bisphenol-A (BPA) is an EDC that disrupts the action of estrogen, and recent work indicates that BPA can affect learning and behavior similarly to estrogen. We exposed red-eared slider turtle (Trachemys scripta) eggs to BPA durin…
Research Grant
Award Number1855240Funding AgencyNational Science FoundationEffective Date2019-09-01Expiration Date2022-08-31Funding Amount$339,999
With this award, the Chemical Synthesis program of the NSF Division of Chemistry is supporting the research of Professor Timothy Lash at Illinois State University to explore the synthesis, characterization, and reactivity of compounds that resemble a class of molecules called "porphyrins". Porphyrins possess many valuable properties and have applications in material science, catalysis and medicine. They also have an impressive array of functions in nature that range from oxygen transportation…
Publication
ID31027806Published Date2019-09-01JournalFood microbiology, 2019-09-01, Volume 82
Although Staphylococcus aureus is a major cause of food poisoning, little is known about its response to growth on food. Utilizing a transcriptional profiling and metabolomics approach, we compared S. aureus grown on autoclaved chicken breast (ACB) to Luria broth agar. ACB cultures demonstrated increased expression of genes associated with protein synthesis, cofactors, secondary metabolites, nitrogen and nucleotide metabolism, amino acid transport, and reduced expression of general stress, li…
Research Grant
Award Number1809024Funding AgencyNational Science FoundationEffective Date2019-09-01Expiration Date2022-08-31Funding Amount$91,444
NONTECHNICAL SUMMARYThis award supports research and education aimed to understand the influence of quantum mechanical interference effects and strong interactions between electrons on the thermoelectric effect in molecule-based materials. The thermoelectric effect reflects the coupling between heat and charge, which makes it possible to directly convert heat into electrical energy in a device which has no moving parts and no operational carbon footprint. In addition to energy harvesting…
Publication
ID31436909Published Date2019-08-22JournalJournal of experimental zoology. Part A, Ecological and integrative physiology, 2019-08-22
Correlated and repeatable patterns of behavior, termed behavioral types, can affect individual fitness. The most advantageous behavioral type may differ across predictable environments (e.g., seasonally), and maternally mediated effects may match hatchling behavior to the environment. We measured righting response, an indicator of behavioral type, of juvenile red-eared slider turtles (Trachemys scripta) emerging from early and late season clutches to understand if the production of behavioral…
Publication
ID31434223Published Date2019-08-20JournalMolecules (Basel, Switzerland), 2019-08-20, Volume 24
Speciation studies are based on fundamental models that relate the properties of biomimetic coordination compounds to the stability of the complexes. In addition to the classic approach based on solution studies, solid state properties have been recently proposed as supporting tools to understand the bioavailability of the involved metal. A ten-year long systematic study of several different complexes of imidazole substituted ligands with transition metal ions led our group to the definition …
Publication
ID31429354Published Date2019-08-20JournalSubstance use & misuse, 2019-08-20
Despite a growing trend in community-based research, studies investigating the influence of multi-level community factors on individual-level outcomes remain relatively sparse. The current study aimed to extend this literature by investigating the association between community disadvantage measured at the community level, and adolescents' substance use over time. Additionally, this study also investigated the influence of parental support and community belonging on this association. Data were…
Publication
ID31322900Published Date2019-08-16JournalThe Journal of organic chemistry, 2019-08-16, Volume 84
Systematic investigation of intramolecular silyloxypyrone-based [5 + 2] cycloadditions revealed three significant factors impacting conversion to cycloadduct: (1) the silyl transfer group has a substantial influence on the rate of reaction, and the robust -butyldiphenylsilyl group was found to be more effective overall than the conventional -butyldimethylsilyl group; (2) α,β-unsaturated esters were generally more reactive than terminal olefins and afforded appreciable quantity of cycloadduct …
Publication
ID31331169Published Date2019-08-16JournalThe Journal of organic chemistry, 2019-08-16, Volume 84
A new family of -dicarbaporphyrinoids has been prepared using the "2 + 2" MacDonald methodology. Dibutylboron triflate catalyzed condensation of 3-iodo-4-methoxybenzaldehyde with an indene enamine afforded an iodofulvene aldehyde, and a related dimethoxyfulvene was similarly prepared in two steps from 2,4-dimethoxybenzaldehyde. Following protection as the corresponding dimethyl acetals, the iodofulvenes were metalated with BuMgLi at -100 °C and reacted with dimethylformamide to give the requi…
Research Grant
Project Number1R35GM133760-01Funding AgencyNational Institutes of HealthEffective Date2019-08-15Expiration Date2020-06-30Funding Amount$277,936
The precise regulation of intra- and inter-cellular signaling events is crucial for the function of biological systems and plays an essential role in human health. Deregulated signaling can perturb cell function by altering the timing or strength of signal activity and can contribute to the pathogenesis of multiple diseases. Signal regulation is accomplished by a variety of intrinsic mechanisms, but signaling can also be manipulated by extrinsic factors including factors derived from other or…
We found 2,290 documents that match your Search
Research Grants: 434
Publications: 1,840
Patents: 12
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