14
14
9
9
17
17
14
14
21
21
34
34
42
42
56
56
88
88
3
3
2019
2010
Research Institution (364)University (342)Hospital (78)Other (19)Foundation (1)
1 - 10 of 364
Sort by
Publication
PubMed ID30240805Published Date2019-01-01JournalJournal of neuroscience methods, 2019-01-01, Volume 311
Imaging measurement of structure alignment has shown increasing importance in determining tissue properties. It is not known if a similar ability for characterizing neuropathology exists.This study aimed to validate a new alignment-assessing method for measuring myelin and axonal properties using quantitative histological metrics. The new method involved analysis of the Fourier transform (FT) power spectrum in standard magnetic resonance imaging (MRI). T-weighted MRI were collected from 10 po…
Publication
PubMed ID30196037Published Date2019-01-01JournalAutonomic neuroscience : basic & clinical, 2019-01-01, Volume 216
The mechanisms underlying bowel dysfunction after high-level spinal cord injury (SCI) are poorly understood. However, impaired supraspinal sympathetic and parasympathetic control is likely a major contributing factor. Disruption of the descending autonomic pathways traversing the spinal cord was achieved by a T3 complete spinal cord transection, and colonic function was examined in vivo and ex vivo four weeks post-injury. Total gastrointestinal transit time (TGTT) was reduced and contractilit…
Publication
PubMed ID30575438Published Date2018-12-21JournalAmerican journal of physiology. Heart and circulatory physiology, 2018-12-21
Cardiovascular diseases (CVD) are highly prevalent in spinal cord injury (SCI) and peripheral vascular dysfunction might be a contributing factor. Recent evidence demonstrates that exposure to heat stress can improve vascular function and reduce the risk of CVD in uninjured populations. We therefore aimed to examine the extent of vascular dysfunction in spinal cord injury (SCI) and the acute effects of passive heating. Fifteen participants with cervical spinal cord injury and fifteen uninjure…
Publication
PubMed ID30526805Published Date2018-12-03JournalCanadian Urological Association journal = Journal de l'Association des urologues du Canada, 2018-12-03
Baseline urodynamic characterization in patients with neurogenic lower urinary tract dysfunction (NLUTD) allows detection of unsafe storage and voiding pressures and optimization of these parameters through medical or surgical intervention. Surveillance urodynamics (sUDS) studies are performed in the ambulatory setting after baseline characterization, with the goal of monitoring bladder function. How often this study should be performed and the circumstances that should prompt repeated studie…
Publication
PubMed ID29904191Published Date2018-12-01JournalSpinal cord, 2018-12-01, Volume 56
Prospective cohort study using the Rick Hansen SCI Registry (RHSCIR) and retrospective medical chart review.To describe treatment patterns of in-patient anti-spasticity medication use following traumatic spinal cord injury (SCI) in acute and rehabilitation hospital settings in British Columbia, Canada.Quaternary trauma center, rehabilitation center.Individuals with traumatic SCI between 2005 and 2014 enrolled in the Vancouver RHSCIR site (N = 917) were eligible for inclusion. Oral and injecta…
Publication
PubMed ID30501555Published Date2018-12-01JournalJournal of neurotrauma, 2018-12-01
Small-scale studies indicate that spinal cord injury (SCI) may lead to significant gastrointestinal and bladder dysfunction. However, how the prevalence of chronic disease related to these dysfunctions compares to non-SCI individuals and whether there are robust relationships to level and severity of injury are still unclear. Here, our goal was to provide high-level evidence on the association between bladder and gastrointestinal dysfunction and SCI using population-level data from the Canadi…
Publication
PubMed ID30503860Published Date2018-11-29JournalThe journal of pain : official journal of the American Pain Society, 2018-11-29
Recent temporal trends in the population prevalence of chronic pain in Canada on a national and provincial level are unknown. Five cycles of the Canadian Community Health Survey (CCHS) (2000/01, 2007/08, 2009/10, 2011/12 and 2013/14) were used to derive population-based estimates of self-reported prevalence of chronic pain. Sensitivity analyses examined chronic pain prevalence among those reporting no other chronic health conditions. The prevalence of chronic pain among the general Canadian p…
Publication
PubMed ID30467135Published Date2018-11-21JournalBMJ open, 2018-11-21, Volume 8
Managing and preventing risk factors associated with cardiovascular and cerebrovascular impairment is well studied in able-bodied individuals. However, individuals with spinal cord injury (SCI) at or above the spinal segment T6 are prone to experience autonomic dysreflexia (AD) but also to suffer from neurogenic detrusor overactivity (NDO). Treatment of NDO would not only improve lower urinary tract function but could also reduce the severity and frequency of life-threatening episodes of AD. …
We found 364 documents that match your Search
Publications: 363
Clinical Trials: 1

Wellspring Search is the world's most comprehensive collection of enriched content about emerging and licensable technology innovations.


Already a member? Sign in