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Publication
PubMed ID29477261Published Date2018-04-11JournalJournal of biomechanics, 2018-04-11, Volume 71
Little is known about the internal mechanics of the in vivo spinal cord during injury. The objective of this study was to develop a method of tracking internal and surface deformation of in vivo rat spinal cord during compression using radiography. Since neural tissue is radio-translucent, radio-opaque markers were injected into the spinal cord. Two tantalum beads (260 µm) were injected into the cord (dorsal and ventral) at C5 of nine anesthetized rats. Four beads were glued to the lateral su…
Publication
PubMed ID29556026Published Date2018-04-01JournalNature neuroscience, 2018-04-01, Volume 21
Abstract not available
Publication
PubMed ID29229580Published Date2018-04-01JournalNeuroImage, 2018-04-01, Volume 169
Detection of functional magnetic resonance imaging (fMRI) activation in white matter has been increasingly reported despite historically being controversial. Much of the development work to-date has used high-field 4 T MRI and specialized pulse sequences. In the current study, we utilized conventional 3 T MRI and a commonly applied gradient-echo-planar imaging sequence to evaluate white matter (WM) fMRI sensitivity within a common framework. Functional WM activity was replicated in target reg…
Publication
PubMed ID29222006Published Date2018-04-01JournalArchives of physical medicine and rehabilitation, 2018-04-01, Volume 99
To create and compare individual and group-based cut-points for wrist accelerometry that correspond to moderate-to-vigorous physical activity (MVPA) in people with spinal cord injury (SCI).Participants completed a graded treadmill-wheeling test while being assessed for oxygen consumption, wrist-acceleration vector magnitude, and spoke acceleration. Oxygen consumption was converted to SCI metabolic equivalents (METs), and linear regression was applied to determine an individualized vector magn…
Publication
PubMed ID29600896Published Date2018-03-30JournalAmerican journal of physiology. Heart and circulatory physiology, 2018-03-30
The capacity of cerebrovasculature to buffer changes in blood pressure (BP) is crucial to prevent stroke, the incidence of which is 3-4 fold elevated after spinal cord injury (SCI). Disruption of descending sympathetic pathways within the spinal cord due to cervical SCI may result in impaired cerebrovascular buffering. Only linear analyses of cerebrovascular buffering of BP, such as transfer function, have been utilized in SCI research. This approach does not account for inherent non-linearit…
Publication
PubMed ID29561565Published Date2018-03-21JournalHealth reports, 2018-03-21, Volume 29
The prevalence of pain among people with a variety of individual neurological conditions has been estimated. However, information is limited about chronic pain among people with neurological conditions overall, and about the conditions for which chronic pain is most prevalent. To fill these information gaps, a common method of pain assessment is required.The data are from the Survey on Living with Neurological Conditions in Canada, a cross-sectional national survey. Based on self-reports, chr…
Publication
PubMed ID29458282Published Date2018-03-15JournalJournal of medical economics, 2018-03-15
A Markov model was used to analyze cost-effectiveness over a lifetime horizon.To investigate the cost-effectiveness of hydrophilic-coated intermittent catheters (HCICs) compared with uncoated catheters (UCs) among individuals with neurogenic bladder dysfunction (NB) due to spinal cord injury (SCI).A Canadian public payer perspective based on data from Ontario; including a scenario analysis from the societal perspective.A previously published Markov decision model was modified to compare the l…
Publication
PubMed ID28325069Published Date2018-06-01JournalDisability and rehabilitation, 2018-06-01, Volume 40
Outdoor activities in natural settings have been found to be beneficial for overall health and well-being. However, people with disabilities may have different experiences accessing outdoor activities in natural settings. This research explored the experiences of users, volunteers, and staff, and perspectives of non-users about an adapted hiking program that uses a specialized mobility device called a TrailRider. The research had three objectives: 1. Describe the experiences of users, volunte…
Publication
PubMed ID29414402Published Date2018-03-01JournalClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2018-03-01, Volume 129
To investigate test-retest reliability of contact heat evoked potentials (CHEPs) from lower extremities using two different stimulation protocols, i.e., normal and increased baseline temperature.A total of 32 able-bodied subjects were included and a subset (N = 22) was retested. CHEPs were recorded from three different dermatomes of the lower extremity (i.e., L2, L5, and S2). Test-retest reliability of CHEPs acquisition after simulation in various lower limb dermatomes using different stimula…
Publication
PubMed ID28770425Published Date2018-03-01JournalMedical & biological engineering & computing, 2018-03-01, Volume 56
Biophysical computational models of axons provide an important tool for quantifying the effects of injury and disease on signal conduction characteristics. Several studies have used generic models to study the average behavior of healthy and injured axons; however, few studies have included the effects of normal structural variation on the simulated axon's response to injury. The effects of variations in physiological characteristics on axonal function were mapped by altering the structure of…
We found 310 documents that match your Search
Publications: 309
Clinical Trials: 1

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