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University (112)Research Institution (42)Hospital (6)Company (2)Investor (1)
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Publication
ID32039851Published Date2020-01-01JournalJournal of Alzheimer's disease : JAD, 2020-01-01, Volume 74
Current advancements in neurovascular biology relates a mechanoceutics treatment, known as cranial osteopathic manipulation (COM), Alzheimer's disease (AD). COM could be used as an evidence-based treatment strategy to improve the symptoms of AD if molecular mechanisms, which currently remain unclear, are elucidated. In the present pilot study, using transgenic rats, we have identified COM mediated changes in behavioral and biochemical parameters associated with AD phenotypes. We expect these …
Publication
ID31659605Published Date2020-01-01JournalAnnals of biomedical engineering, 2020-01-01, Volume 48
Physical differences between youth and adults, which include incomplete myelination, limited neck muscle development, and a higher head-body ratio in the youth population, likely contribute towards the increased susceptibility of youth to concussion. Previous research efforts have considered the biomechanics of concussion for adult populations, but these known age-related differences highlight the necessity of quantifying the risk of concussion for a youth population. This study adapted the p…
Research Grant
Project Number5K23AT009568-02Funding AgencyNational Institutes of HealthEffective Date2019-08-01Expiration Date2020-07-31Funding Amount$164,840
Program Director/Principal Investigator (Liu, Wei): Abstract The overall goal of this mentored career development award (K23) is to support Wei Liu, PhD to become an independent investigator in the field of complementary and alternative medicine (CAM) and chronic pain, with a focus on biofeedback Tai Chi intervention development and testing. Disabilities that arise from typical impairments of knee osteoarthritis (OA) include decreased muscle strength, reduced range of motion, and decreased ae…
Patent
Publication NumberUS 20190105045Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2018-09-06Publication Date2019-04-11
A dual-directional, or multi-degree-of-freedom, surgical clip is provided. The clip includes a top clamp. A bottom clamp is hingedly connected to the top clamp at a hinged joint for mutually pivotal transverse motion about the hinged joint. The top and bottom clamps each include a hinged attachment at an extreme end thereof. A first portion of each of the top and bottom clamps is in hinged connection with a corresponding second portion of the respective top and bottom clamps for mutually pivo…
Publication
ID30553788Published Date2019-02-05JournalEuropean journal of pharmacology, 2019-02-05, Volume 844
N-methyl D-aspartate (NMDA) receptors play a crucial role in normal brain function, pathogenesis of neurodegenerative and psychiatric disorders. Functional tetra-heteromeric NMDA receptor contains two obligatory GluN1 subunits and two identical or different non-GluN1 subunits that evolve from six different genes including four GluN2 (A-D) and two GluN3 (A-B) subunits. Since NMDA receptors confer varied physiological properties and spatiotemporal distributions in the brain, pharmacological age…
Research Grant
Project Number1K23AT009568-01A1Funding AgencyNational Institutes of HealthEffective Date2018-08-15Expiration Date2019-07-31Funding Amount$164,840
Program Director/Principal Investigator (Liu, Wei): Abstract The overall goal of this mentored career development award (K23) is to support Wei Liu, PhD to become an independent investigator in the field of complementary and alternative medicine (CAM) and chronic pain, with a focus on biofeedback Tai Chi intervention development and testing. Disabilities that arise from typical impairments of knee osteoarthritis (OA) include decreased muscle strength, reduced range of motion, and decreased ae…
Publication
ID29273359Published Date2018-02-01JournalThe Journal of surgical research, 2018-02-01, Volume 222
The purpose of this study is to determine if antioxidant supplementation influences the incidence of atrial arrhythmias in trauma intensive care unit (ICU) patients.In this retrospective pre-post study, critically ill injured patients aged ≥18 years, admitted to a single-center trauma ICU for ≥48 hours were eligible for inclusion. The control group consists of patients admitted from January 2000 to September 2005, before routine antioxidant supplementation in our ICU. The antioxidant group co…
Patent
Publication NumberUS D799696Filing StatusIssued PatentAvailabilityUnknownFiling Date2015-06-18Publication Date2017-10-10
Publication
ID28451864Published Date2017-08-01JournalClinical orthopaedics and related research, 2017-08-01, Volume 475
Proliferative therapy, or prolotherapy, is a controversial treatment method for many connective tissue injuries and disorders. It involves the injection of a proliferant, or irritant solution, into the site of injury, which causes small-scale cell death. This therapeutic trauma is theorized to initiate the body's wound-healing cascade, perhaps leading to tissue repair. The immediate effects of many of these proliferants are poorly characterized, as are the cellular responses to them; here, we…
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Research Grants: 15
Publications: 80
Patents: 8
Clinical Trials: 9

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