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Clinical Trial
Clinical Trial IDNCT03867058Start Date2020-03-01Completion Date2025-03-01Study TypeObservationalStatusNot yet recruiting
In this study, investigators will examine how temporal rate processing might be affected when the width of neural excitation narrows. The manipulation of neural excitation width will be achieved for example by changing electrode configurations or stimulating single versus multiple electrodes simultaneously. Investigators will then measure if the extent to which rate processing is affected by spatially restricted stimulation can predict a subject's overall speech recognition and predict also w…
Publication
ID30526191Published Date2020-03-01JournalJournal of applied gerontology : the official journal of the Southern Gerontological Society, 2020-03-01, Volume 39
With the urgent need to increase and improve mental health care of the growing population of older adults in the United States, clinical research is warranted to further the knowledge and improve the relevant training for mental health professionals working with older adults. This study drew from two diverse clinical samples of adults ages 18 years to 80 years to examine whether and how initial clinical presentations and changes over time in individual, family-of-origin, and relational measur…
Clinical Trial
Clinical Trial IDNCT03866850Start Date2020-03-01Completion Date2025-03-01Study TypeObservationalStatusNot yet recruiting
In this study, the investigators will study one of the basic biophysical properties of the auditory nerve, charge integration, behaviorally (detection threshold versus phase duration functions). The investigators will compare charge integration in two subject groups: congenitally deafened and deafened at a later age in life. The investigators will then examine if behaviorally estimated neural excitation patterns differ between short phase duration and long phase duration stimulation. Lastly, …
Publication
ID31446782Published Date2020-03-01JournalThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2020-03-01, Volume 57
To investigate the dimensions of the tensor veli palatini (TVP) muscle using high image resolution 3-dimensional magnetic resonance imaging (MRI) of the soft palate among children with normal velopharyngeal and craniofacial anatomy and to compare values to individuals with a diagnosis of 22q11.2 deletion syndrome (22q11DS). We also sought to determine whether there is a relationship between hypoplasia of the TVP and severity of middle ear dysfunction and hearing loss.Three-dimensional MRI wer…
Clinical Trial
Clinical Trial IDNCT03867032Start Date2020-03-01Completion Date2025-12-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
In this study, the investigators will evaluate whether auditory training with speech-related acoustic features in psychophysical testing will help CI subjects improve speech recognition. The primary endpoint is the speech recognition measures.
Publication
ID31874571Published Date2020-03-01JournalHealth promotion practice, 2020-03-01, Volume 21
Implementing tobacco-free policies on university campuses has become increasingly common. However, promoting policy compliance remains a challenge. It is important to develop strategies that can overcome barriers to successful policy implementation and promote compliance. This Practice Note presents a case study of a practical strategy for addressing poor implementation of a newly adopted tobacco-free policy. Following principles of advocacy research, a team of student researchers and a facul…
Publication
IDDOI:10.1175/mwr-d-19-0279.1Published Date2020-03-01JournalMonthly Weather Review, 2020-03-01, Volume 148
This study examines the geographic and temporal characteristics of the springtime transition to the summer precipitation regime of isolated convection in the southeastern (SE) United States during 2009–12, using a high-resolution surface radar-based precipitation dataset. Isolated convection refers herein to isolated elements or small clusters of precipitation in radar imagery less than 100 km in horizontal dimension. Though the SE United States does not have a monsoon climate, it is useful t…
Publication
ID32048977Published Date2020-02-12JournalCurrent clinical pharmacology, 2020-02-12
Constipation is a highly prevalent functional gastrointestinal disorder that may significantly affect the quality of life and health care costs. Treatment for constipation has been broadly reviewed by cognitive therapies, medications, and surgical interventions. Gut microbiota such as Bifidobacterium, Clostridium, Bacteroidetes, and Lactobacilli have been demonstrated in functional gastrointestinal disorders and prebiotics play a role in augmenting their presence. Prebiotics are ingredients i…
Publication
IDDOI:10.1200/jco.2020.38.5_suppl.98Published Date2020-02-10JournalJournal of Clinical Oncology, 2020-02-10, Volume 38
98 Background: Immunotherapy related thyroid abnormalities are well described. Any grade abnormality has been reported in 6-18% of patients. The clinical relevance of thyroid abnormalities in a real-world setting is still unclear. In this retrospective study, we analyzed immunotherapy type with time to thyroid dysfunction, grade of thyroid dysfunction, and number that ultimately required treatment. Methods: We retrospectively collected data for patients who received immunotherapy from April 2…
Publication
ID32035422Published Date2020-02-08JournalAging, 2020-02-08, Volume 12
Recent studies have revealed a resemblance of a HIF-regulated heart and brain glycolytic profiles prompting the hypothesis that the classical cell-to-cell lactate shuttle observed between astrocytes and neurons operates also in heart - between cardiac fibroblasts and cardiomyocytes. Here, we demonstrate that co-culturing of cardiomyocytes with cardiac fibroblasts leads to orchestrated changes in expression and/or localization pattern of glucose metabolism enzymes and lactate transport protein…
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Research Grants: 1,491
Publications: 12,522
Patents: 471
Clinical Trials: 405
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