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Publication
ID31240285Published Date2019-07-21JournalLab on a chip, 2019-07-21, Volume 19
Over the past several decades, a litany of acoustofluidic devices have been developed which purport to have significant advantages over traditional benchtop analytical tools. These acoustofluidic devices are frequently labeled as "labs-on-chips"; however, many do an insufficient job of limiting their dependence on the lab. Often, acoustofluidic devices still require skilled operators and complex external equipment. In an effort to address these shortcomings, we developed a low-cost, expandabl…
Publication
ID30989691Published Date2019-07-20JournalStatistics in medicine, 2019-07-20, Volume 38
In existing benefit-risk assessment (BRA) methods, benefit and risk criteria are usually identified and defined separately based on aggregated clinical data and therefore ignore the individual-level differences as well as the association among the criteria. We proposed a Bayesian multicriteria decision-making method for BRA of drugs using individual-level data. We used a multidimensional latent trait model to account for the heterogeneity of treatment effects with latent variables introducing…
Publication
ID31164224Published Date2019-07-19JournalJournal of biomechanics, 2019-07-19, Volume 92
Post-mortem human subjects (PMHS) are frequently used to characterize biomechanical response and injury tolerance of humans to various types of loading by means of instrumentation installed directly on the skeleton. Data extracted from such tests are often used to develop and validate anthropomorphic test devices (ATDs), which function as human surrogates in tests for injury assessment. Given that the location and orientation of installed instrumentation differs between subjects, nominally si…
Publication
ID30711659Published Date2019-07-15JournalActa biomaterialia, 2019-07-15, Volume 93
Although bone tissues possess an intrinsic capacity for repair, there are cases where bone healing is either impaired or insufficient, such as fracture non-union, osteoporosis, osteomyelitis, and cancers. In these cases, treatments like surgical interventions are used, either alone or in combination with bioactive agents, to promote tissue repair and manage associated clinical complications. Improving the efficacy of bioactive agents often requires carriers, with biomaterials being a pivotal …
Publication
ID31005575Published Date2019-07-15JournalJournal of neuroscience methods, 2019-07-15, Volume 323
Autocorrelation (AC) in fMRI time-series is a well-known phenomenon, typically attributed to colored noise and therefore removed from the data. We hypothesize that AC reflects systematic and meaningful signal fluctuations that may be tied to neural activity and provide evidence to support this hypothesis.Each fMRI time-series is modeled as an autoregressive process from which the autocorrelation is quantified. Then, autocorrelation during resting-state fMRI and auditory oddball (AOD) task in …
Publication
ID31068425Published Date2019-07-15JournalJournal of virology, 2019-07-15, Volume 93
The benefits of mucosal vaccines over injected vaccines are difficult to ascertain, since mucosally administered vaccines often induce serum antibody responses of lower magnitude than those induced by injected vaccines. This study aimed to determine if mucosal vaccination using a modified vaccinia virus Ankara expressing human immunodeficiency virus type 1 (HIV-1) gp120 (MVAgp120) prime and a HIV-1 gp120 protein boost could be optimized to induce serum antibody responses similar to those indu…
Publication
IDIEEE:8734791Published Date2019-07-15JournalIEEE Transactions on Signal Processing, 2019-07-15, Volume 67
Anomaly detection is a hot topic in hyperspectral signal processing. The key point of hyperspectral anomaly detection is the modeling of the background. In this paper, we propose a novel anomaly detection method via global and local joint modeling of background. Based on the observation that the local three-dimensional patch belonging to the background in hyperspectral image (HSI) usually lies in a low dimensional manifold, we propose to reconstruct the background part of a HSI from its subsa…
Research Grant
Award Number1851075Funding AgencyNational Science FoundationEffective Date2019-07-15Expiration Date2022-06-30Funding Amount$345,160
For most of the last century, the equatorward spread of cold water masses from high latitudes in the Labrador and Nordic Seas was expected to be largely contained along the Deep Western Boundary Current in the subpolar and subtropical North Atlantic. Since the turn of this century, observational floats launched within these water masses have defied this expectation. Instead, myriad interior pathways have been revealed across the North Atlantic. Contemporaneously, an inventory of anthropogenic…
Publication
ID31087384Published Date2019-07-30JournalStatistics in medicine, 2019-07-30, Volume 38
Time trends of lung cancer prevalence and mortality are the result of three competing processes: changes in the incidence rate, stage-specific survival, and ascertainment at early stages. Improvements in these measures act concordantly to improve disease-related mortality, but push the prevalence rate in opposite directions making a qualitative interpretation difficult. The goal of this paper is to evaluate the relative contributions of these components to changes in lung cancer prevalence an…
Publication
ID31066438Published Date2019-07-11JournalFaraday discussions, 2019-07-11, Volume 216
Dexter energy transfer in chemical systems moves an exciton (i.e., an electron-hole pair) from a donor chromophore to an acceptor chromophore through a bridge by a combination of bonded and non-bonded interactions. The transition is enabled by both one-electron/one-particle and two-electron/two-particle interaction mechanisms. Assuming that there is no real intermediate state population of an electron, hole, or exciton in the bridge, the transport involves two states that are coupled non-adia…
We found 124,365 documents that match your Search
Research Grants: 34,935
Publications: 78,972
Patents: 6,289
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