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Publication
ID31655651Published Date2019-11-15JournalInternational journal of radiation oncology, biology, physics, 2019-11-15, Volume 105
Abstract not available
Publication
ID31484039Published Date2019-11-15JournalNeuroImage, 2019-11-15, Volume 202
Segmenting the continuous speech stream into units for further perceptual and linguistic analyses is fundamental to speech recognition. The speech amplitude envelope (SE) has long been considered a fundamental temporal cue for segmenting speech. Does the temporal fine structure (TFS), a significant part of speech signals often considered to contain primarily spectral information, contribute to speech segmentation? Using magnetoencephalography, we show that the TFS entrains cortical responses …
Publication
ID31325855Published Date2019-11-15JournalThe Science of the total environment, 2019-11-15, Volume 691
Mounting evidence suggests that short-term exposure to ozone increases the risk of asthma exacerbations. However, ozone exposures have been assessed using ambient ozone concentrations averaged over different time periods in different studies.To evaluate the risks for asthma exacerbations related to ambient ozone measured as 1-hour or 8-hour daily maximum and 24-hour average concentrations.Based on a literature search in PubMed, EMBASE and Web of Science, we identified all time-series studies …
Publication
ID31501281Published Date2019-11-15JournalJournal of bacteriology, 2019-11-15, Volume 201
The mitis group streptococci include the major human pathogen and the opportunistic pathogens and , which are human oral cavity colonizers and agents of bacteremia and infective endocarditis in immunocompromised patients. Bacterial membrane lipids play crucial roles in microbe-host interactions; for many pathogens, however, the composition of the membrane is poorly understood. In this study, we characterized the lipidomes of selected species of mitis group streptococci and investigated the me…
Publication
ID30734280Published Date2019-11-15JournalInternational journal of cancer, 2019-11-15, Volume 145
Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression. In the present study, we comprehensively assessed associations of 14,522 common single-nucleotide polymorphisms (SNPs) in 149 genes of the fatty-acid synthesis pathway with cutaneous melanoma disease-specific survival (CMSS). The dataset of 858 cutaneous melanoma (CM) patients from a published genome-wide association…
Publication
ID31597706Published Date2019-11-15JournalJournal of immunology (Baltimore, Md. : 1950), 2019-11-15, Volume 203
Neonates often develop poor immunity against intracellular pathogens. Because CD8 T cells are essential for eliminating infectious agents, it is crucial to understand why they behave differently in early life. Previous studies in mice have demonstrated that neonatal CD8 T cells fail to form memory because of an intrinsic propensity to differentiate into short-lived effectors. However, the underlying mechanisms remain undefined. We now show that neonatal CD8 T cells exhibit higher glycolytic a…
Publication
ID31326804Published Date2019-11-15JournalThe Science of the total environment, 2019-11-15, Volume 691
Ballast water is a vector for global translocation of microorganisms, and should be monitored to protect human and environmental health. This study utilizes high throughput sequencing (HTS) and machine learning to examine the bacterial and fungal microbiomes of ballast water to identify associations between 16S and 18S rRNA genes and the fungal ITS region. These sequencing regions were examined using the SILVA v132 and UNITE reference databases. The highest correlation was found between the c…
Publication
ID31288116Published Date2019-11-10JournalThe Science of the total environment, 2019-11-10, Volume 690
Severe air pollution in the Pearl River Delta (PRD) region of southern China has increased attention of both the scientific community and policy makers. Air quality data collected at the PRD Regional Air Quality Monitoring Network during 2006-2015 were analyzed for assessing the effectiveness of pollution control measures and for estimating the trends of premature mortality attributable to ambient PM and O. Statistically significant decreasing trends were detected for PM (-1.74 to -1.83 μg m …
Publication
ID31482721Published Date2019-11-20JournalAntioxidants & redox signaling, 2019-11-20, Volume 31
Ubiquitin is a highly conserved protein modifier that heavily accumulates during the oxidative stress response. Here, we investigated the role of the ubiquitination system, particularly at the linkage level, in the degradation of oxidized proteins. The function of ubiquitin in the removal of oxidized proteins remains elusive because of the wide range of potential targets and different roles that polyubiquitin chains play. Therefore, we describe in detail the dynamics of the K48 ubiquitin resp…
Publication
ID31671486Published Date2019-11-20JournalClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2019-11-20, Volume 17
The present study aimed to observe potential benefit of aripiprazole augmentation in the treatment of major depressive disorder with mixed specifier (MDDM) in naturalistic treatment setting.Data were collected from MDDM patients using a retrospective chart review for 8 weeks (week -8 and week 0) in routine practice. All patients were on current antidepressants upon starting of aripiprazole. Patients were treated without restriction of doses of aripiprazole. The primary endpoint was the mean c…
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