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Publication
ID32533830Published Date2020-07-01JournalFEMS microbiology ecology, 2020-07-01, Volume 96
Ectomycorrhizal (ECM) fungal communities show temporal dynamics. Such dynamics have been mainly assessed with 1 year of investigations and have been related to the seasonal changes in environment. Recent study in sub-tropical region has revealed that stochastic temporal-based process can affect ECM fungal community, making the community of the same season different between years. The different community structures across years have also been observed in the Arctic region with a grass host. Ne…
Publication
ID32612132Published Date2020-07-01JournalScientific reports, 2020-07-01, Volume 10
Using echolocation, bats receive acoustic information on their surroundings, which is assumed to help them sophisticatedly navigate complex environments. In this study, to understand spatial learning and acoustic sensing in bats, we investigated how flight and echolocation control changed in Rhinolophus ferrumequinum nippon as they learnt about their surroundings in an obstacle course that they flew through repeatedly. In these experiments, two testing environments (acoustically permeable and…
Publication
ID32366381Published Date2020-06-29JournalMolecular and cellular biology, 2020-06-29, Volume 40
Proteasomes are protease complexes essential for cellular homeostasis, and their activity is crucial for cancer cell growth. However, the mechanism of how proteasome activity is maintained in cancer cells has remained unclear. The CNC family transcription factor NFE2L1 induces the expression of almost all proteasome-related genes under proteasome inhibition. Both and its phylogenetically closest homolog, , are highly expressed in several types of cancer, such as colorectal cancer. Here, we de…
Publication
ID32605138Published Date2020-06-27JournalInternational journal of molecular sciences, 2020-06-27, Volume 21
Elucidation of the genomic mechanism that guides the cell-fate change is one of the fundamental issues of biology. We previously demonstrated that whole genome expression is coordinated by the emergence of a critical point at both the cell-population and single-cell levels through the physical principle of self-organized criticality. In this paper, we further examine the genomic mechanism that determines the cell-fate changes from embryo to cancer development. The state of the critical point,…
Publication
ID32513685Published Date2020-06-23JournalProceedings of the National Academy of Sciences of the United States of America, 2020-06-23, Volume 117
A high rate of synaptic vesicle (SV) release is required at cerebellar mossy fiber terminals for rapid information processing. As the number of release sites is limited, fast SV reloading is necessary to achieve sustained release. However, rapid reloading has not been observed directly. Here, we visualize SV movements near presynaptic membrane using total internal reflection fluorescence (TIRF) microscopy. Upon stimulation, SVs appeared in the TIRF-field and became tethered to the presynaptic…
Publication
ID32479728Published Date2020-06-16JournalLangmuir : the ACS journal of surfaces and colloids, 2020-06-16, Volume 36
A novel water-soluble amino acid derived vinyl polymer whose block sequence was designed to achieve a gradient thermoresponsiveness along a chain was accurately prepared through an ultrarapid reversible addition-fragmentation chain-transfer polymerization. The polymer exhibited unique temperature-regulated self-assembly in water, leading to multiple nanostructural transformations including disassembly-to-ordered and ordered-to-ordered transitions. The morphologies were drastically changed by …
Publication
ID32499373Published Date2020-06-04JournalThe Journal of biological chemistry, 2020-06-04
Huntington disease (HD) is a neurodegenerative disorder caused by expanded CAG repeats in the Huntingtin gene. Results from previous studies have suggested that transcriptional dysregulation is one of the key mechanisms underlying striatal medium spiny neuron (MSN) degeneration in HD. However, some of the critical genes involved in HD etiology or pathology could be masked in a common expression profiling assay because of contamination with non-MSN cells. To gain insight into the MSN-specific …
Publication
ID32490529Published Date2020-06-03JournalThe journals of gerontology. Series A, Biological sciences and medical sciences, 2020-06-03
Appropriate energy intake (EI) is essential to prevent frailty. Because self-reported EI is inaccurate and has systematic errors, adequate biomarker calibration is required. This study examined the association between doubly labeled water (DLW)-calibrated EI and the prevalence of frailty among community-dwelling older adults.A cross-sectional study was performed using baseline data of 7022 older adults aged ≥65 years in the Kyoto-Kameoka Study. EI was evaluated using a validated food frequenc…
Publication
ID32201261Published Date2020-06-01JournalThe American journal of pathology, 2020-06-01, Volume 190
Amyloid β-proteins (Aβs) Aβ1-42 and Aβ1-43 are converted via two product lines of γ-secretase to Aβ1-38 and Aβ1-40. This parallel stepwise processing model of γ-secretase predicts that Aβ1-42 and Aβ1-43, and Aβ1-38 and Aβ1-40 are proportional to each other, respectively. To obtain further insight into the mechanisms of parenchymal Aβ deposition, these four Aβ species were quantified in insoluble fractions of human brains (Brodmann areas 9 to 11) at various Braak senile plaque (SP) stages, usi…
Publication
IDDOI:10.4028/www.scientific.net/kem.846.72Published Date2020-06-01JournalKey Engineering Materials, 2020-06-01, Volume 846
This paper describes basic property in semi-solid forging method of magnesium alloy AZX1311. In the semi-solid forging process, an arbitrary fraction of solid is selected at a temperature between the liquidus and the solidus line and rapidly cooled and coagulated simultaneously with deformation of the material in a die to obtain a product. In addition, the magnesium alloy AZX1311 has excellent castability and mechanical properties. In recent years, the use of magnesium alloys for home electri…
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Publications: 7,480
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