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Publication
ID32450341Published Date2020-08-01JournalBone, 2020-08-01, Volume 137
Patients with type 1 Diabetes Mellitus (T1DM) have an increased risk of fracture. Little is known about the microarchitecture of trabecular bone in T1DM, which may account for some of the increased risk. We report here a secondary analysis comparing Trabecular Bone Score (TBS) derived from DXA to 2-D histomorphometric and 3-D micro-computerized tomography (CT) variables obtained from iliac biopsies in 83 subjects (29 T1DM and 54 controls). The transilial bone biopsy specimens were fixed, embe…
Publication
ID31877296Published Date2020-08-01JournalThe Annals of thoracic surgery, 2020-08-01, Volume 110
The longevity of a stentless valve in a younger population (20-60 years old) is unknown.From 1992 to 2015, 1947 patients underwent aortic valve/root replacement for aortic stenosis, insufficiency, root aneurysm, or aortic dissection with stentless bioprostheses (median size, 26 mm). At operation 105 patients were
Publication
ID32487799Published Date2020-08-01JournalCurrent opinion in obstetrics & gynecology, 2020-08-01, Volume 32
The purpose of this publication is to review the currently available and most up-to-date information regarding the pathogenesis, diagnosis, and treatment of pelvic congestion syndrome.The diagnosis of pelvic congestion syndrome is difficult to make; however, it should remain on the differential for chronic pelvic pain. The most recent available research seems to favour endovascular treatment with interventional radiology over surgical management, with high success rate and low occurrence of c…
Publication
ID31754869Published Date2020-08-01JournalClinical oral investigations, 2020-08-01, Volume 24
This study aimed to compare dentin bond durability under different degradation conditions between two etch-and-rinse (ER) systems and a universal adhesive in ER mode.This study used a universal adhesive [Scotchbond Universal (SU)], a three-step ER adhesive [Scotchbond Multi-Purpose Plus (SM)], and a two-step ER adhesive [Single Bond Plus (SB)]. A phosphoric acid-etching agent was applied to bovine dentin prior to the application of either a primer or the adhesive. After acid etching, bonding …
Publication
ID30987503Published Date2020-08-01JournalJournal of pharmacy practice, 2020-08-01, Volume 33
Diffuse alveolar hemorrhage (DAH) is bleeding into the alveolar space of the lungs. Pirfenidone is an antifibrotic agent that is approved for the treatment of idiopathic pulmonary fibrosis (IPF). The most commonly reported side effects include gastrointestinal and skin-related events. We present 3 cases of hemoptysis and DAH among patients on pirfenidone therapy for IPF.An 88-year-old female, a 75-year-old male, and a 73-year-old male all with IPF on pirfenidone presented with hemoptysis and …
Publication
ID32699437Published Date2020-08-01JournalThe Linacre quarterly, 2020-08-01, Volume 87
This article illustrates the tensions between the precepts of the and the Accreditation Council for Graduate Medical Education as they apply to education in obstetrics and gynecology, and argues that moving forward, Catholic sponsorship of obstetric and gynecologic residencies now requires transparency, authenticity, and reflection in order to mitigate these inherent tensions.
Publication
ID32632850Published Date2020-08-01JournalAdvances in therapy, 2020-08-01, Volume 37
To date, no study has reported the prevalence of cannabis use in chronic pain patients. The aim of this study is to investigate the trends in cannabis use among chronic pain in-patients from 2011 to 2015 in the USA.Patients were identified from the National Inpatient Sample (NIS) database using the International Classification of Diseases, Ninth and Tenth Revision, diagnosis codes for chronic pain and cannabis use. Annual estimates and trends were determined for cannabis use, patient characte…
Publication
ID32720363Published Date2020-07-27JournalJournal of cardiac surgery, 2020-07-27
Although the standard treatment of infective endocarditis (IE) is antimicrobial therapy, surgical intervention is required in some cases. However, the optimal timing of surgery remains unclear. Hence, we conducted a population-based analysis using the National Inpatient Sample (NIS) database to assess the outcomes of early versus late surgery in patients with native valve IE.We queried the NIS database for all hospitalized patients between 2006 and 2016 with a primary diagnosis of IE who had …
Publication
ID32513872Published Date2020-07-24JournalThe Journal of biological chemistry, 2020-07-24, Volume 295
The causative factors underlying conformational conversion of cellular prion protein (PrP) into its infectious counterpart (PrP) during prion infection remain undetermined, in part because of a lack of monoclonal antibodies (mAbs) that can distinguish these conformational isoforms. Here we show that the anti-PrP mAb PRC7 recognizes an epitope that is shielded from detection when glycans are attached to Asn-196. We observed that whereas PrP is predisposed to full glycosylation and is therefore…
Publication
IDCSHL:2020.07.23.218636Published Date2020-07-24JournalbioRxiv, 2020-07-24
Although radiotherapy and most cancer drugs target the proliferation of cancer cells, it is metastasis, the complex process by which cancer cells spread from the primary tumor to other tissues and organs of the body where they form new tumors, that leads to over 90% of all cancer deaths. Thus, there is an urgent need for anti-metastasis strategies alongside chemotherapy and radiotherapy. An important step in the metastatic cascade is migration. It is the first step in metastasis via local inv…
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Research Grants: 982
Publications: 9,448
Patents: 122
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