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IDIEEE:9116058Published Date2020-07-15Conference2020 3rd IEEE International Conference on Soft Robotics (RoboSoft)
A peristaltic continuous mixing conveyor that focuses on the mechanism of the intestine has been developed as a technology for the mixing and transport of a solid-liquid mixture and high viscosity fluids. The developed peristaltic continuous mixing conveyor succeeded in the mixing and transport of such mixtures in a previous study. A simple cyclic pattern is currently used as the movement pattern of the system, and the control method can be further improved. In this study, we aim to realize a…
Publication
ID32165209Published Date2020-07-01JournalSteroids, 2020-07-01, Volume 159
Phthalates and bisphenol A (BPA) are estrogenic endocrine disruptors. Polymorphisms in the gene encoding estrogen receptor 1 (ESR1) may contribute to the ratio of the lengths of the second and fourth digits (2D:4D), which is considered an index of prenatal exposure to sex hormones. Thus, we investigated whether ESR1 polymorphisms modify the effects of prenatal exposure to phthalates and BPA on 2D:4D in a birth cohort. Maternal serum in the first trimester was used to determine prenatal exposu…
Publication
ID32294535Published Date2020-07-01JournalComparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2020-07-01, Volume 245
To clarify the relationships between growth, endocrine status and habitat characteristics in Japanese eel (Anguilla japonica), plasma and stomach mRNA levels of ghrelin were examined in wild eels captured in the river and the bay, and in cultured eels during and after experimental fasting. Wild juvenile eels captured in freshwater habitats within the river showed significantly higher plasma and stomach mRNA levels of ghrelin than did fish obtained from brackish-water habitats within the bay. …
Publication
ID32462261Published Date2020-07-01JournalBreast cancer research and treatment, 2020-07-01, Volume 182
Chemotherapy-induced amenorrhea (CIA) is one of the critical side effects from the chemotherapy in premenopausal patients with breast cancer. The goals of our study are the following: (1) to investigate the factors affecting the incidence of CIA; and (2) to evaluate the prognostic role of CIA in premenopausal patients with breast cancer.We conducted a post hoc retrospective substudy to examine the incidence of the CIA and the relationship between CIA and prognosis in NSAS-BC02 that compared t…
Publication
IDDOI:10.1163/24519391-00501002Published Date2020-06-19JournalAsia-Pacific Journal of Ocean Law and Policy, 2020-06-19, Volume 5
This paper aims to explain how Japanese MPAs are established, managed, and implemented based on different laws. It introduces the definition of MPAs adopted within the governmental agencies and the relevant policy documents that describe the government's intention to expand MPAs in Japan. It then discusses the first and second largest types of MPAs in Japan, which represent centralized and community-based types of MPAs, respectively. It also touches upon the 2019 amendment to Japan’s Nature C…
Publication
ID32468817Published Date2020-06-19JournalThe Journal of organic chemistry, 2020-06-19, Volume 85
The asymmetric 1,3-dipolar cycloaddition of glycine imino esters to 1-propene-1,3-sultone or sulfocoumarins is described. The reaction was efficiently catalyzed by Cu(MeCN)BF/DTBM-Segphos or Cu(MeCN)BF/Bu-FcPhox at room temperature to afford fused pyrrolidines as single regioisomers with excellent diastereoselectivity and enantioselectivity. The broad substrate scope of this reaction provides convenient access to structurally diverse multisubstituted pyrrolidines in an optically pure fashion.
Publication
ID32294313Published Date2020-06-17JournalChemistry, an Asian journal, 2020-06-17, Volume 15
A facile and convenient synthesis of the chiral phthalide framework catalyzed by cationic iridium was developed. The method utilized cationic iridium/bisphosphine-catalyzed asymmetric intramolecular carbonyl hydroacylation of 2-keto benzaldehydes to furnish the corresponding optically active phthalide products in good to excellent enantioselectivities (up to 98% ee). The mechanistic studies using a deuterium-labelled substrate suggested that the reaction involved an intramolecular carbonyl in…
Publication
ID32222534Published Date2020-06-15JournalGene, 2020-06-15, Volume 743
Meiotic crossover (CO) recombination initiates from programmed DNA double-strand breaks (DSBs) around hotspots, and results in reciprocal exchange of chromosome segments between homologous chromosomes (homologs). COs are crucial for most sexually-reproducing organisms because they promote accurate chromosome segregation and create genetic diversity. Therefore, faithful accomplishment of CO formation is ensured in many ways, but the bases of the regulation are not fully understood. Our previou…
Publication
ID32364747Published Date2020-06-09JournalLangmuir : the ACS journal of surfaces and colloids, 2020-06-09, Volume 36
Deformation of liposomes, or lipid vesicles, has been investigated extensively in terms of the thermodynamic equilibrium of the bending energy of the lipid bilayer membrane. However, the range of such deformation in previous literature has been limited within the moderate surface-to-volume ratio of the vesicles, in which axisymmetric shapes are dominant. Here, we show that neuron-like morphology, in which many lipid tubes extend radially from the mother vesicle, becomes dominant upon the slow…
Publication
IDIEEE:9130517Published Date2020-06-04Conference2020 IEEE 15th International Conference of System of Systems Engineering (SoSE)
Technical infrastructure such as bridges and tunnels are critical in economic activities, but in recent years, aging of them has progressed, and demand for checking the soundness of them is expanding. There are several technologies to inspect the aging process of the structures to find cracks on a wall or flacking inside of concrete. Among the technologies to diagnose a structure, the hammering test is a traditional, easy, simple, and effective method. We developed an AI hammering checker by …
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