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Publication
ID32113851Published Date2020-06-08JournalProgress in neuro-psychopharmacology & biological psychiatry, 2020-06-08, Volume 100
Glycogen synthase kinase 3β (GSK3β) has gained interest regarding its involvement in psychiatric and neurodegenerative disorders. Recently GSK3 inhibitors were highlighted as promising rescuers of cognitive impairments for a gamut of CNS disorders. Growing evidence supports that fast-spiking parvalbumin (PV) interneurons are critical regulators of cortical computation. Albeit, how excitatory receptors on PV interneurons are regulated and how this affects cognitive function remains unknown. To…
Publication
ID32427789Published Date2020-06-01JournalAdvances in skin & wound care, 2020-06-01, Volume 33
To discuss prevention strategies that can mitigate the frequency of tracheostomy-related wound complications.A systematic literature review of PubMed between 2010 and 2019.Full-text articles written in English language and studying human participants younger than 18 years.The primary outcome was the rate of tracheostomy-related skin complications after implementation of a given intervention. Secondary outcomes included rates of accidental decannulation or other complications.A total of 348 st…
Publication
ID32275118Published Date2020-06-01JournalPediatric blood & cancer, 2020-06-01, Volume 67
Differentiated thyroid cancer (DTC) is the most common childhood thyroid malignancy. The standard of care for pediatric DTC is total thyroidectomy followed by radioactive iodine (RAI) treatment when indicated. Molecular changes and potential therapeutic targets have been recently described in pediatric thyroid cancer. Pediatric oncologists are increasingly involved in the evaluation of thyroid nodules in childhood cancer survivors and in the management of advanced thyroid cancer. In 2015, the…
Publication
ID32362230Published Date2020-06-01JournalHypertension (Dallas, Tex. : 1979), 2020-06-01, Volume 75
Hypertension is associated with cardiovascular events in adults. Subclinical changes to left ventricular strain and diastolic function have been found before development of decreased left ventricular ejection fraction and cardiovascular events. Our objective was to study effects of blood pressure (BP) on ventricular function in youth across the BP spectrum. Vital signs and labs were obtained in 346 participants aged 11 to 19 years who had BP categorized as low-risk (N=144; systolic BP
Publication
ID32317593Published Date2020-06-01JournalCritical care medicine, 2020-06-01, Volume 48
To assess the evidence and discuss the risks and clinical relevance of ketamine for the treatment of various disease states impacting the adult critically ill population.A literature review was performed using PubMed evaluating primary literature published until August 2018.Case reports, observational studies (cohort, case-control), and randomized controlled trials involving patients 18 years and older in a nonperioperative setting using either IV or intramuscular ketamine were included for a…
Publication
ID32088922Published Date2020-06-01JournalJournal of reconstructive microsurgery, 2020-06-01, Volume 36
In the pediatric population, bony defects of the extremities pose a significant challenge for which free vascularized fibular grafts (FVFGs) represent a valuable reconstructive option. The purpose of this study was to explore surgical outcomes, complications, and long-term functionality of FVFG for this patient group. Using MEDLINE and PubMed databases, studies were identified of pediatric extremity reconstruction using FVFG which reported functional outcomes and/or complications. The operati…
Publication
ID32052249Published Date2020-06-01JournalJournal of clinical psychology in medical settings, 2020-06-01, Volume 27
We conducted a pilot randomized control trial (RCT) to simultaneously examine the feasibility of effectively implementing Cognitive Remediation Therapy (CRT) for adolescents with anorexia nervosa (AN) during medical hospitalization at a single-site hospital center. Employment of this protocol occurred on a general medical unit with diverse medical admitting diagnoses, not an eating disorder floor of a hospital and not part of a structured inpatient anorexia nervosa treatment program. This was…
Publication
ID32412716Published Date2020-06-01JournalThe American journal of surgical pathology, 2020-06-01, Volume 44
Giant cell tumor of bone (GCT) is a benign locally aggressive neoplasm composed of mononuclear cells admixed with innumerable osteoclast-type giant cells. H3F3A gene mutations producing mutant histone protein product H3.3 have been identified in 96% of GCT; mutant H3.3 is reliably demonstrated by immunohistochemistry. GCT may contain woven bone and rarely, neoplastic cartilage nodules which causes diagnostic challenges with aggressive neoplasms such as osteosarcoma. We describe the features o…
Publication
ID32149923Published Date2020-06-01JournalMedical care, 2020-06-01, Volume 58
Following birth, women may access preventive care in adult settings or, with their infants, in pediatric settings. Preventive care can improve future birth outcomes and long-term health, particularly for women with health risks.This cohort study linked mother-infant Medicaid claims from 12 states for 2007-2011 births. Pregnancy claims identified health risk categories: maternal cardiovascular (diabetes, hypertension, pre-eclampsia, obesity), maternal mental health (depression, anxiety), and p…
Publication
ID31797095Published Date2020-06-01JournalPediatric nephrology (Berlin, Germany), 2020-06-01, Volume 35
Kidney transplant is the renal replacement therapy (RRT) of choice for children with end stage kidney disease (ESKD). Only 21.3% of children who initiate RRT receive a preemptive kidney transplant (PKT). We characterized the transition to RRT in children in the CKiD cohort including the prevalence of dialysis as first RRT vs. PKT and graft survival.258 children enrolled in CKiD have initiated RRT, and 202 had post-RRT initiation data collected through phone or in-person follow-up. Characteris…
We found 35,333 documents that match your Search
Research Grants: 8,275
Publications: 24,984
Patents: 1,390
Clinical Trials: 668
Web Documents: 16

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