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University (753)Research Institution (56)Hospital (31)Foundation (7)Company (2)
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Publication
ID31858867Published Date2020-04-01JournalPharmaceutical development and technology, 2020-04-01, Volume 25
Tocosol™ is a tocopherol-based paclitaxel (PTX) nanoemulsion consisting of α-tocopherol (α-T) isomer of vitamin E as a solubilizer and vitamin E TPGS as the primary emulsifier. Despite its positive attributes in early clinical studies, it failed the pivotal phase III clinical trials. The long-term goal of this work was to reformulate Tocosol™. In this study, Tocosol™ formulation was optimized by replacing the α-T isomer with the more pharmacological active isomer γ-tocotrienol (γ-T), and the …
Publication
IDDOI:10.1177/0018578720910397Published Date2020-03-05JournalHospital Pharmacy, 2020-03-05
Burnout remains an emerging challenge in healthcare. Burnout in these settings has been associated with compromised personal wellbeing, decreased work productivity, higher healthcare costs, decreased patient satisfaction, and deteriorating quality of patient care. As pharmacist roles on healthcare teams expand, health-system pharmacy leaders should be cognizant of burnout, including risk factors and identification. Coordinated efforts should foster pharmacist wellbeing and resilience, individ…
Publication
ID31903101Published Date2020-02-01JournalJournal of drug delivery science and technology, 2020-02-01, Volume 55
This study investigated the cytotoxic effects of gemcitabine-loaded solid lipid nanoparticle (Gem-SLN) on the patient-derived primary pancreatic cancer cell lines (PPCL-46) and MiaPaCa-2. Different SLN formulations were prepared from glyceryl monostearate (GMS), polysorbate 80 (Tween® 80) and poloxamer 188 (Pol 188) as surfactants using a cold homogenization method. Gem-SLN was characterized for particle size and charge distribution, entrapment efficiency and loading capacity. Fourier Transfo…
Publication
ID31860294Published Date2020-01-22JournalJournal of the American Chemical Society, 2020-01-22, Volume 142
A key characteristic of organic photovoltaic cells is the efficient charge separation in the active layer. Sufficient delocalization of the positive polaron in organic photovoltaics is considered essential for the effective separation of the opposite charges and the suppression of recombination. We use light-induced EPR and ENDOR spectroscopy combined with DFT calculations to determine the electronic structure of the positive polaron in PTB7-type oligomers. Utilizing the superior spectral res…
Publication
ID31683009Published Date2020-01-01JournalInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2020-01-01, Volume 77
HIV-1 is the most common and pathogenic strain of human immunodeficiency virus consisting of many subtypes. To study the difference among HIV-1 subtypes in infection, diagnosis and drug design, it is important to identify HIV-1 subtypes from clinical HIV-1 samples. In this work, we propose an effective numeric representation called Subsequence Natural Vector (SNV) to encode HIV-1 sequences. Using the representation, we introduce an improved linear discriminant analysis method to classify HIV-…
Publication
IDDOI:10.1177/2158244019899420Published Date2020-01-01JournalSAGE Open, 2020-01-01, Volume 10
Preschool students are expelled from educational settings at higher rates than any other students, and this may serve to be problematic across their lifespan. One of the primary reasons reported is due to their display of social behavioral problems within the preschool classroom. A historical review of social behavioral interventions for preschool children in classroom settings was provided. Moreover, a meta-analysis of recent evidenced-based social behavioral interventions for children with …
Publication
ID31756249Published Date2020-01-01JournalAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020-01-01, Volume 77
To examine the reporting rates of adverse drug events (ADEs) with apixaban and empagliflozin as reports move up to the next level of spontaneous reporting.This was a retrospective cohort study of outpatients who discontinued apixaban or empagliflozin within 3 years of Food and Drug Administration (FDA) approval. We enriched the sample using an active surveillance strategy to identify subsets of patients with International Classification of Diseases (ICD) codes possibly associated with an ADE.…
Publication
ID32165947Published Date2019-12-15JournalOpen access Macedonian journal of medical sciences, 2019-12-15, Volume 7
The failure of mucus clearance in bronchiectasis can be improved by chest physiotherapy or/and mucoactive agents.To assess the effects of long-term use of carbocysteine on frequency and duration of exacerbations in patients with bronchiectasis.We performed an observational, non-randomized, open study (a real-life study) including 64 patients with bronchiectasis divided into two groups, examined group (EG) and control group (CG). All participants were treated with appropriate treatment for the…
Publication
IDIEEE:9006569Published Date2019-12-12Conference2019 IEEE International Conference on Big Data (Big Data)
The goal of this project is to timely identify and characterize hot topics discussed on the Chinese microblogging website, Sina Weibo. First, we develop a subject-oriented crawler to retrieve Weibo posts. Second, a probabilistic topic model is applied to the dataset to identify prominent topics and keywords. A comparison on hot topics, Word Cloud, and Latent Dirichlet Allocation results are discussed, followed by future research directions.
Publication
ID31563612Published Date2019-12-01JournalMolecular phylogenetics and evolution, 2019-12-01, Volume 141
Using numerical methods for genome comparison has always been of importance in bioinformatics. The Chaos Game Representation (CGR) is an effective genome sequence mapping technology, which converts genome sequences to CGR images. To each CGR image, we associate a vector called an Extended Natural Vector (ENV). The ENV is based on the distribution of intensity values. This mapping produces a one-to-one correspondence between CGR images and their ENVs. We define the distance between two DNA seq…
We found 753 documents that match your Search
Research Grants: 277
Publications: 475
Patents: 1

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