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Publication
ID32278271Published Date2020-06-01JournalBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020-06-01, Volume 126
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and one of the most lethal. MGN-3/Biobran is a natural product derived from rice bran hemicelluloses and has been reported to possess a potent anticancer effect in a clinical study of patients with HCC. The current study examines the mechanisms by which Biobran protects against chemically induced hepatocarcinogenesis in rats. The chemical carcinogen used in this study is N-nitrosodiethylamine (NDEA) plus carbon tetr…
Publication
ID32006900Published Date2020-05-01JournalBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020-05-01, Volume 125
A greater understanding of factors causing cancer initiation, progression and evolution is of paramount importance. Among them, the serine/threonine phosphatase PPM1D, also referred to as wild-type p53-induced phosphatase 1 (Wip1) or protein phosphatase 2C delta (PP2Cδ), is emerging as an important oncoprotein due to its negative regulation on a number of crucial cancer suppressor pathways. Initially identified as a p53-regulated gene, PPM1D has been afterwards found amplified and more recent…
Research Grant
Project Number5R25MD007610-09Funding AgencyNational Institutes of HealthEffective Date2020-05-01Expiration Date2021-04-30Funding Amount$540,000
PROJECT SUMMARY/ABSTRACT The proposed CDU-CRECD Mentored Postdoctoral Training in Translational Research and Biomedical Informatics Program at Charles R. Drew University (CDU) is a mentored clinical research and career development program designed to develop a diverse cadre of clinical and translational investigators who conduct innovative research on the underlying causes of diseases that disproportionately impact minority populations in the United States (e.g., cancer, drug use and addictio…
Research Grant
Project Number1R25DA050723-01A1Funding AgencyNational Institutes of HealthEffective Date2020-04-01Expiration Date2021-03-31Funding Amount$273,408
Underrepresented minority researchers and researchers from disadvantaged backgrounds are underrepresented in both research in general and in funding from NIDA. The Next Generation Substance Abuse Disorders Research Training at Charles R. Drew University (CDU) and UCLA (NGSART-CU; to be known as SART) builds on 15 years of DIDARP/MIDARP program (PI: Friedman) in which 125 mostly minority students received a meaningful research experience in substance use disorder fields along with training and…
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$247,826
Project Summary/Abstract Despite the prevention and treatment efforts of the past 30 years, Latino men who have sex with men (MSM) continue to be disproportionately impacted by HIV: diagnoses increased 14% between 2010-2014 and those younger than 40 years old had the highest incidence rates. HIV biomedical interventions to reduce HIV infections are not reaching Latino communities. Nearly 300,000 Latinos in the nation were eligible for HIV pre- exposure prophylaxis (PrEP) in 2015, yet only 7,6…
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$274,125
Abstract Research collaborations and partnerships have fostered and facilitated the ability of CDU investigators to explore new opportunities and expand their research horizons beyond their areas of expertise. The University has a rich history of successful intramural and extramural research partnerships and collaborations. The collaborative integration of academic and community expertise has enhanced the ability of the University and community partners to respond to a wide variety of health …
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$326,592
Abstract: The Purpose of this study is to determine how social and epigenomic factors that are associated with social determinants of health cause increase in Obesity and Comorbidities, resulting in increased risk for breast cancer. Specifically, this study will examine cancer health disparities associated with obesity and other comorbidities in African American and Latina populations residing South Los Angeles. Multiple reasons have been presented in the literature suggesting both socioecono…
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$306,336
Abstract The obesity epidemic has led to and without intervention, will continue to lead to a large increase in health care costs in the US. Innovative, high-volume programs are needed to address the obesity epidemic. However, a literature review reveals that there is no consensus for optimal weight loss programs leading to a great need for innovative weight loss programs, particularly those that address underserved populations. Traditional provider- patient visits usually involve one provide…
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$128,550
Abstract CDU?s RCMI AXIS Recruitment Core will recruit at least two nationally renowned and respected senior investigators with expertise in addressing health disparities research. The Recruitment Core in partnership with the Deans, Department Chairs and Faculty at CDU will conduct a national search that will ensure that applicants from underrepresented backgrounds are actively sought out. We will engage national and local academic partners and collaborators. These individuals will have demon…
Research Grant
Project Number5U54MD007598-12Funding AgencyNational Institutes of HealthEffective Date2020-03-01Expiration Date2021-02-28Funding Amount$492,493
Investigator Development Core Abstract The development of highly competitive and independent research faculty has been a goal at CDU since its establishment. The AXIS Center has been focused on achieving this goal in the last 10 years with measurable success on establishing a cohort of young faculty who advanced in their academic appointments, in securing independent funding and increasing not only their productivity, but also the quality in terms of number of citations and impact factor of p…
We found 1,479 documents that match your Search
Research Grants: 1,302
Publications: 142
Patents: 3
Clinical Trials: 32

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