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Patent
Publication NumberUS 20200157628Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-11-25Publication Date2020-05-21
Methods of determining the risk of ASD in an individual are provided which comprise identifying the presence of one or more genomic mutations in one or more of the genes, PTCHD1, SHANK3, NFIA, DPP6, DPP10, DYPD, GPR98, PQBP1, ZNF41 and FTSJ1.
Research Grant
Project Number1R61MH120188-01A1Funding AgencyNational Institutes of HealthEffective Date2020-05-01Expiration Date2021-04-30Funding Amount$1,026,903
PROJECT SUMMARY DESCRIPTION: People with schizophrenia spectrum disorders (SSDs) (i.e., schizophrenia, schizoaffective disorder, schizophreniform disorder) exhibit considerable impairment in social functioning. Current treatments are minimally effective, and impairments tend to persist. Our recent collaborative multi-center study increased knowledge regarding the neurobiology of social cognitive (SCog) impairment in people with SSDs, identifying the neural circuitry of SCog impairments and th…
Research Grant
Project Number1R01AA028224-01Funding AgencyNational Institutes of HealthEffective Date2020-04-10Expiration Date2021-03-31Funding Amount$374,206
PROJECT SUMMARY/ABSTRACT Alcohol use has been identified as a major risk factor for the global burden of death, disease and injury. Given the high levels of overall volume of alcohol use, detrimental drinking patterns, and high levels of alcohol-attributable mortality and burden of disease, Lithuania recently implemented three of the most effective alcohol control policies within a short time span: increase in taxation, reduction of availability of alcoholic beverages, and a ban on advertisem…
Clinical Trial
Clinical Trial IDNCT04338464Start Date2020-08-01Completion Date2021-08-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
The mental health sector is being called upon to develop and implement interventions for youth that attend to gender, age and cultural diversity (Mental Health Commission of Canada, 2016). The proposed project outlines the development and feasibility testing of a culturally driven transdiagnostic psychosocial intervention for South Asian women aged 16-24 years. We will recruit 30 participants to complete the 12 week psychosocial intervention. Pre, midpoint and post evaluations will be complet…
Research Grant
Project Number5R01MH118311-02Funding AgencyNational Institutes of HealthEffective Date2020-04-01Expiration Date2021-03-31Funding Amount$516,549
DESCRIPTION: Over the past decades, antidepressants and psychotherapy have been the first-line treatments for LLD. Despite being safe and well-tolerated, a large number of patients do not achieve full and persistent remission after initial treatment. About 50% of patients with LLD do not respond after two antidepressant trials, meeting the consensus definition of treatment resistance (TR-LLD). The persistence of chronic and elevated depressive symptoms in older adults has significant clinical…
Research Grant
Project ID888692Funding AgencyCommunity Research and Development Information ServiceEffective Date2020-09-01Expiration Date2023-08-31Funding Amount$253,514
Neurodegenerative diseases affect more than 6 million people in Europe, and its prevalence is growing as population ages, hence it is a timeliness health challenge we are facing as a society. Parkinsonism is the 2nd most prevalent neurodegenerative form, being Parkinson’s disease (PD) the most frequent, whereas 20% of the patients are diagnosed with atypical parkinsonisms (AP). Despite presenting some clinical overlap, AP tends to be more therapy-resistant and have faster degeneration rates t…
Clinical Trial
Clinical Trial IDNCT04325958Start Date2020-09-01Completion Date2024-09-01PhaseN/AStudy TypeInterventionalStatusNot yet recruiting
Epidemiological studies suggest that the use of cannabis is associated with an increase in the risk of motor vehicle collisions. It is also known that younger users may be at increased risk for motor vehicle collisions. Further, the frequency with which cannabis is used may be an important variable in determining the effects of cannabis on driving. The purpose of the present study will be to investigate the effects of cannabis on simulated driving in young as compared to middle-aged drivers. …
Patent
Publication NumberUS 10577657Filing StatusIssued PatentAvailabilityUnknownFiling Date2018-03-07Publication Date2020-03-03
The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences and proteins in medical diagnosis and treatment of neuropsychiatric disorders or development disorders.
Patent
Publication NumberUS 10577658Filing StatusIssued PatentAvailabilityUnknownFiling Date2018-03-07Publication Date2020-03-03
The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences and proteins in medical diagnosis and treatment of neuropsychiatric disorders or development disorders.
Clinical Trial
Clinical Trial IDNCT04181008Start Date2020-03-01Completion Date2021-01-01PhaseEarly Phase 1Study TypeInterventionalStatusNot yet recruiting
This study is a single-center, open-label study of the plasma pharmacokinetics of amiloride nasal spray at three different doses in healthy volunteers.
We found 736 documents that match your Search
Research Grants: 372
Publications: 9
Patents: 85
Clinical Trials: 257
Opportunities: 13

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