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Patent
Publication NumberUS 20170266377Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2015-05-14Publication Date2017-09-21
The subject technology is embodied in a method for predicting a delivery rate of a plurality of drugs dispensed by multiple infusion pumps at a delivery point. The method includes receiving one or more operating parameters related to multiple drug pumps and a carrier fluid pump, wherein each of the drug pumps dispenses a drug, and the carrier fluid pump dispenses a carrier fluid. The method also includes determining a delivery rate of a first drug at the delivery point. This can be done by pr…
Patent
Publication NumberUS 9764087Filing StatusIssued PatentAvailabilityUnknownFiling Date2012-11-20Publication Date2017-09-19
Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow and dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junctio…
Patent
Publication NumberUS 9187540Filing StatusIssued PatentAvailabilityUnknownFiling Date2007-10-29Publication Date2015-11-17
The present invention features compositions and methods of treating or preventing hypertension or a cardiac indication. In particular embodiments, the invention provides E2F2 as a new therapeutic target for the treatment of hypertension or a cardiac indication, and methods of increasing the expression and/or activity of E2F2.
Patent
Publication NumberUS 9095580Filing StatusIssued PatentAvailabilityUnknownFiling Date2011-11-21Publication Date2015-08-04
In accordance with the present invention, EC progenitors can be used in a method for regulating angiogenesis, i.e., enhancing or inhibiting blood vessel formation, in a selected patient and in some preferred embodiments for targeting specific locations. For example, the EC progenitors can be used to enhance angiogenesis or to deliver an angiogenesis modulator, e.g. anti- or pro-angiogenic agents, respectively to sites of pathologic or utilitarian angiogenesis. Additionally, in another embodim…
Patent
Publication NumberUS 8969023Filing StatusIssued PatentAvailabilityUnknownFiling Date2009-06-10Publication Date2015-03-03
Aspects of the invention relate to methods and compositions for treating Alzheimer's disease (AD). In some embodiments, the invention provides methods for screening and identifying compounds that selectively inhibit the targeting of the insulin-Akt signaling pathway by Aβ oligomers.
Patent
Publication NumberUS 8747905Filing StatusIssued PatentAvailabilityUnknownFiling Date2007-10-29Publication Date2014-06-10
As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells.
Patent
Publication NumberUS 8679835Filing StatusIssued PatentAvailabilityUnknownFiling Date2009-06-30Publication Date2014-03-25
Provided herein are an isolated or enriched population of tumor initiating cells derived from normal cells, cells susceptible to neoplasia, or neoplastic cells. Methods of use of the cells for screening for anti-hyperproliferative agents, and use of the cells for animal models of hyperproliferative disorders including metastatic cancer, diagnostic methods, and therapeutic methods are provided.
Patent
Publication NumberUS 20130218080Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2011-05-24Publication Date2013-08-22
Systems for predicting a drug delivery profile as described herein include at least one drug pump that produces a drug flow. The drug pump dispenses at least a first drug. The system also includes at least one carrier fluid pump that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system furt…
Clinical Trial
Clinical Trial IDNCT01781039Start Date2013-01-01Completion Date2024-08-01Study TypeObservationalStatusRecruiting
Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of the inner ear and auditory neurons on speech discrimination performance in quiet and in noise. This information may be used as a predictor of hearing aid benefi…
Clinical Trial
Clinical Trial IDNCT01582477Start Date2012-03-01Completion Date2012-07-01PhasePhase 4Study TypeInterventionalStatusCompleted
The purpose of the study is to assess the safety and efficacy of EXPAREL when administered via infiltration into the transversus abdominis plane (TAP) to prolonged postsurgical analgesia in men undergoing robot-assisted laparoscopic prostatectomy.
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Patents: 76
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