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Patent
Publication NumberUS 20200163929Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2020-01-31Publication Date2020-05-28
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.
Patent
Publication NumberUS 20200121633Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-12-23Publication Date2020-04-23
The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Patent
Publication NumberUS 20200087253Filing StatusPatent ApplicationAvailabilityUnknownFiling Date2019-11-15Publication Date2020-03-19
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release HNO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of …
Patent
Publication NumberJP 6656345 B2Filing StatusIssued PatentAvailabilityUnknownFiling Date2018-12-05Publication Date2020-02-06
Patent
Publication NumberUS 10548872Filing StatusIssued PatentAvailabilityUnknownFiling Date2019-03-29Publication Date2020-02-04
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration.
Patent
Publication NumberHR P20191919 T1Filing StatusOtherAvailabilityUnknownFiling Date2019-10-23Publication Date2020-01-10
The disclosed subject matter provides N- substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Patent
Publication NumberSI 3284463 T1Filing StatusOtherAvailabilityUnknownFiling Date2014-01-17Publication Date2019-12-31
The disclosed subject matter provides N- substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Patent
Publication NumberUS 10517847Filing StatusIssued PatentAvailabilityUnknownFiling Date2019-01-08Publication Date2019-12-31
The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Patent
Publication NumberPL 3284463 T3Filing StatusOtherAvailabilityUnknownFiling Date2014-01-17Publication Date2019-12-31
The disclosed subject matter provides N- substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Patent
Publication NumberNZ 748771 AFiling StatusPatent ApplicationAvailabilityUnknownFiling Date2014-01-17Publication Date2019-12-20
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration, and include pharmaceutical compositions that comprise a N-hydroxysulfonamide type nitroxyl donor and an aqueous buffer, wherein the N-hydroxysulfonamide type nit…
We found 333 documents that match your Search
Patents: 323
Clinical Trials: 6
SEC Filings: 4

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