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Publication
ID32062544Published Date2020-06-05JournalJournal of hazardous materials, 2020-06-05, Volume 391
Whether cadmium ingestion affects the susceptibility to infection and the detailed mechanism have not been investigated. We aimed to evaluate the effects of cadmium on the intestinal mucosal barrier and Salmonella infection. We found that oral administration of cadmium caused damage to the intestinal mucosal barrier, with body weight loss, an increase in inflammation, significantly reduced Muc2 expression and goblet cell loss in the intestine. The effect of cadmium on secretory cell different…
Publication
ID32370870Published Date2020-06-08JournalAnalytica chimica acta, 2020-06-08, Volume 1115
Nucleic acids are important biomarkers for disease detection, monitoring, and treatment. Advances in technologies for nucleic acid analysis have enabled discovery and clinical implementation of nucleic acid biomarkers. However, challenges remain with technologies for nucleic acid analysis, thereby limiting the use of nucleic acid biomarkers in certain contexts. Here, we review single-molecule technologies for nucleic acid analysis that can be used to overcome these challenges. We first discus…
Publication
ID32238524Published Date2020-06-01JournalThorax, 2020-06-01, Volume 75
Pulmonary cysts and spontaneous pneumothorax are presented in most patients with Birt-Hogg-Dubé (BHD) syndrome, which is caused by loss of function mutations in the () gene. The pathogenic mechanisms underlying the cystic lung disease in BHD are poorly understood.Mesenchymal was specifically deleted in mice or in cultured lung mesenchymal progenitor cells using a Cre/loxP approach. Dynamic changes in lung structure, cellular and molecular phenotypes and signalling were measured by histology, …
Publication
ID32324618Published Date2020-06-01JournalAmerican journal of physical medicine & rehabilitation, 2020-06-01, Volume 99
As physicians specializing in rehabilitation medicine consider sequelae from the novel coronavirus pandemic that began in 2019, one issue that should be top of mind is the physiologic effect that large-scale social distancing had on the health of patients in general but, more specifically, on preoperative patients who had their surgeries delayed or will have newly scheduled procedures during the peripandemic period. Predictably, as the virus becomes less prevalent, there will be a tremendous …
Publication
ID32242325Published Date2020-06-01JournalDermatology and therapy, 2020-06-01, Volume 10
Psoriasis (PsO) is a common, systemic, chronic, inflammatory disease characterized by key clinical symptoms, including itching, pain, and scaling. PsO is associated with a high prevalence of comorbidities, including other autoimmune diseases and malignancies. Furthermore, special populations, such as pregnant, pediatric, and elderly patients, and those with erythrodermic PsO, are challenging to treat and require tightly monitored disease and treatment management. Because certain populations h…
Publication
ID31881295Published Date2020-06-01JournalJournal of the American Academy of Dermatology, 2020-06-01, Volume 82
Renal involvement in adult Henoch-Schönlein purpura is a major cause of morbidity and can lead to significant long-term renal impairment. The prognostic significance of normal or minimal urinary abnormalities at diagnosis is unknown.To assess the risk of long-term renal impairment in patients with Henoch-Schönlein purpura who present with normal or minimal urinary abnormalities.Retrospective cohort study of adult Henoch-Schönlein purpura patients presenting with normal urinalysis results, mic…
Publication
ID32046871Published Date2020-06-01JournalThe Journal of arthroplasty, 2020-06-01, Volume 35
The direct anterior approach (DAA) is increasingly used for total hip arthroplasty (THA). Although the DAA can reduce pain, recovery time, and dislocations in nondysplastic hips, few studies report its results in patients with severe dysplasia. We aimed to evaluate outcomes of primary THA through the DAA with cup placement at the true acetabulum in hips with severe dysplasia.We retrospectively evaluated 23 consecutive patients (29 hips) who underwent THA by DAA for osteoarthritis secondary to…
Publication
ID32168094Published Date2020-06-01JournalDiseases of the colon and rectum, 2020-06-01, Volume 63
Most hospitals in the United States are reimbursed for colectomy via a bundled payment based on the diagnosis-related group assigned. Enhanced recovery after surgery programs have been shown to improve the value of colorectal surgery, but little is known about the granular financial tradeoffs required at individual hospitals.The purpose of this study is to analyze the index-hospitalization impact on specific cost centers associated with enhanced recovery after surgery implementation for diagn…
Publication
ID31924517Published Date2020-06-01JournalJournal of shoulder and elbow surgery, 2020-06-01, Volume 29
Baseline anatomic data of the humerus are limited by difficulties in quantifying humeral version and the neck-shaft angle (NSA). This study used a 3-dimensional digitizer to quantify normative values for these variables and to identify possible correlations with demographic categories of age, sex, race, and lateralization.Measurements from 1104 cadaveric humeri were collected with a MicroScribe G2 digitizer, which produced 3-dimensional positional data of the proximal and distal humeral artic…
Publication
ID32209646Published Date2020-06-01JournalDiabetes care, 2020-06-01, Volume 43
To identify sleep duration trajectories from early to middle adulthood and their associations with incident type 2 diabetes.Using a group-based modeling approach, we identified sleep duration trajectories based on sleep duration in ages 20-25, 26-35, 36-45, and 46+ years, which were retrospectively assessed in 2009 among 60,068 women from the Nurses' Health Study II (median age 54.9 years) who were free of diabetes, cardiovascular disease, and cancer. We investigated the prospective associati…
We found 112,874 documents that match your Search
Research Grants: 23,105
Publications: 82,418
Patents: 5,631
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