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Publication
ID32146990Published Date2020-04-01JournalClinics in podiatric medicine and surgery, 2020-04-01, Volume 37
Researchers often do not publish negative results; positive outcome reported bias remains rampant. This problem is pervasive throughout the medical continuum. Failure to release less than favorable results could be construed as ethically and morally inappropriate. Failure to make public less than favorable outcomes stifles the scientific process and is contrary to the precepts of the Declaration of Helsinki and the World Health Organization. Sponsors and researchers must embrace the ideal of …
Publication
ID32146980Published Date2020-04-01JournalClinics in podiatric medicine and surgery, 2020-04-01, Volume 37
Gaseous nitric oxide under increased atmospheric pressure (gNOp) has shown ability to kill multidrug-resistant bacteria in an in vitro model and in a live mammalian (porcine) model. Factors impacting the kill rate of the multidrug-resistant bacteria include atmospheric pressures, concentration of gaseous NO, flow rate, and duration of application. Using successful in vitro parameters, gNOp showed multilog reduction of bacteria in a live mammalian (porcine) model. The in vitro testing system, …
Publication
ID32130001Published Date2020-03-13JournalJournal of chemical information and modeling, 2020-03-13
Binding of muscarinic ligands, both antagonists and agonists, and their effects on the conformation of the M acetylcholine receptor were modeled and compared to experimental data. After docking of antagonists to the M receptor in an inactive conformation (3UON, 5ZK3, 5ZKB, or 5ZKB) and agonists in an active conformation (4MQS), 100 ns of conventional molecular dynamics (MD) followed by 500 ns of accelerated MD was run. Conventional MD revealed ligand-specific interactions with the receptor. A…
Publication
ID32028254Published Date2020-02-06JournalJournal of sport & exercise psychology, 2020-02-06
The authors tested the notion that expertise effects would be more noticeable when access to situational information was reduced by occluding (i.e., noncued) or freezing (i.e., cued) the environment under temporal constraints. Using an adaptation of tasks developed by Ward, Ericsson, and Williams, the participants viewed video clips of attacking soccer plays frozen or occluded at 3 temporal points and then generated and prioritized situational options and anticipated the outcome. The high-ski…
Publication
ID31894996Published Date2020-02-01JournalJournal of consulting and clinical psychology, 2020-02-01, Volume 88
The Acculturative Process and Context Framework (Ward & Geeraert, 2016) proposes that acculturative stressors influence psychological well-being over time. In fact, extant literature has linked bicultural stress with psychological functioning; yet, no studies have explored the causal dominance of bicultural stress. The purpose of the present study was to evaluate the directionality of prospective relations among bicultural stress and psychosocial functioning (i.e., depressive symptoms, hopefu…
Research Grant
Award Number1930076Funding AgencyNational Science FoundationEffective Date2020-02-01Expiration Date2025-01-31Funding Amount$650,000
This project will contribute to the national need for highly skilled scientists, mathematicians, engineers, and technicians. It will do so by supporting the retention and graduation of high-achieving, low-income students with demonstrated financial need at Barry University. The project will provide four-year scholarships to a single cohort of up to 15 students. These Scholars will pursue Bachelor?s degrees in biology, chemistry, computer information science, computer science, or mathematics. …
Publication
ID31910288Published Date2020-01-07JournalBritish journal of pharmacology, 2020-01-07
More than 30% of currently marketed medications act via GPCRs. Thus, GPCRs represent one of the most important pharmacotherapeutic targets. In contrast to traditional agonists activating multiple signalling pathways, agonists activating a single signalling pathway represent a new generation of drugs with increased specificity and fewer adverse effects.We have synthesized novel agonists of muscarinic ACh receptors and tested their binding and function (on levels of cAMP and inositol phosphates…
Publication
ID31691579Published Date2020-01-01JournalJournal of comparative effectiveness research, 2020-01-01, Volume 9
Determine the effectiveness of hypothermically stored amniotic membrane (HSAM) versus standard of care (SOC) in diabetic foot ulcers (DFUs). A randomized controlled trial was conducted on 76 DFUs analyzed digitally. Cox wound closure for HSAM (38 wounds) was significantly greater (p = 0.04) at weeks 12 (60 vs 38%), and 16 (63 vs 38%). The probability of wound closure increased by 75% (Hazard Ratio = 1.75; 95% CI: 1.16-2.70). HSAM showed >60% reductions in area (82 vs 58%; p = 0.02) and depth …
Publication
ID30239986Published Date2020-01-01JournalChild development, 2020-01-01, Volume 91
Acculturation consists of multiple domains (i.e., cultural practices, identifications, and values). However, less is known about how acculturation processes influence each other across multiple domains of acculturation. This study was designed to investigate transition patterns of acculturative processes within and across domains in a sample of 302 recent-immigrant Hispanic adolescents, M (SD) = 14.51 years (0.88) at baseline; male = 53%). Adolescents were assessed six times over a 3-year per…
Publication
ID31876510Published Date2020-01-01JournalWounds : a compendium of clinical research and practice, 2020-01-01, Volume 32
Impaired wound healing is estimated to affect about 2% of the US population, and a major goal of health care providers (HCPs) is to better understand delayed healing so they can effectively choose advanced wound dressings to manage these wounds. However, there are estimated to be more than 3000 dressing options available, making dressing selection an overwhelming burden. An expert panel of 7 HCPs experienced in diverse medical disciplines and 3 scientists convened to discuss the use of 2 fami…
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Research Grants: 207
Publications: 669
Patents: 12
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